Zobrazeno 1 - 10
of 573
pro vyhledávání: '"E. A. Larson"'
Publikováno v:
Tomography, Vol 9, Iss 5, Pp 1592-1602 (2023)
Background: This study aimed to develop a time-efficient method of acquiring simultaneous, dual-slice MR spectroscopic imaging (MRSI) for the evaluation of brain metabolism. Methods: Adaptive Hadamard-encoded pulses were developed and integrated with
Externí odkaz:
https://doaj.org/article/d1c43c00ff2e44629018cde42effcc8b
Autor:
Stephen M. Moore, James D. Quirk, Andrew W. Lassiter, Richard Laforest, Gregory D. Ayers, Cristian T. Badea, Andriy Y. Fedorov, Paul E. Kinahan, Matthew Holbrook, Peder E. Z. Larson, Renuka Sriram, Thomas L. Chenevert, Dariya Malyarenko, John Kurhanewicz, A. McGarry Houghton, Brian D. Ross, Stephen Pickup, James C. Gee, Rong Zhou, Seth T. Gammon, Henry Charles Manning, Raheleh Roudi, Heike E. Daldrup-Link, Michael T. Lewis, Daniel L. Rubin, Thomas E. Yankeelov, Kooresh I. Shoghi
Publikováno v:
Tomography, Vol 9, Iss 3, Pp 995-1009 (2023)
Preclinical imaging is a critical component in translational research with significant complexities in workflow and site differences in deployment. Importantly, the National Cancer Institute’s (NCI) precision medicine initiative emphasizes the use
Externí odkaz:
https://doaj.org/article/c03b45b43e1546d4a22efc4f2e820217
Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI
Autor:
Sule I. Sahin, Xiao Ji, Shubhangi Agarwal, Avantika Sinha, Ivina Mali, Jeremy W. Gordon, Mark Mattingly, Sukumar Subramaniam, John Kurhanewicz, Peder E. Z. Larson, Renuka Sriram
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 736-749 (2023)
Metabolite-specific echo-planar imaging (EPI) sequences with spectral–spatial (spsp) excitation are commonly used in clinical hyperpolarized [1-13C]pyruvate studies because of their speed, efficiency, and flexibility. In contrast, preclinical syste
Externí odkaz:
https://doaj.org/article/763209506d174be688ddd0fa55f4861f
Autor:
Nikolaj Bøgh, Jeremy W. Gordon, Esben S. S. Hansen, Robert A. Bok, Jakob U. Blicher, Jasmine Y. Hu, Peder E. Z. Larson, Daniel B. Vigneron, Christoffer Laustsen
Publikováno v:
Tomography, Vol 8, Iss 2, Pp 585-595 (2022)
Background: Magnetic resonance imaging (MRI) with hyperpolarized [1-13C]pyruvate allows real-time and pathway specific clinical detection of otherwise unimageable in vivo metabolism. However, the comparability between sites and protocols is unknown.
Externí odkaz:
https://doaj.org/article/172b7fb37f15430288b80059eb4b1140
Autor:
Pavithra Viswanath, Georgios Batsios, Joydeep Mukherjee, Anne Marie Gillespie, Peder E. Z. Larson, H. Artee Luchman, Joanna J. Phillips, Joseph F. Costello, Russell O. Pieper, Sabrina M. Ronen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Telomerase expression and the alternative lengthening of telomeres pathway are hallmarks of cancer. Here, the authors show that, in primary brain tumors, these features are correlated with metabolic signatures detectable by metabolic imaging, suggest
Externí odkaz:
https://doaj.org/article/6f6728adc1b44addb32041508ef50b6c
68Ga-PSMA-11 PET/MRI: determining ideal acquisition times to reduce noise and increase image quality
Autor:
Vishnu Murthy, Raven L. Smith, Dora H. Tao, Courtney A. Lawhn-Heath, Dave E. Korenchan, Peder E. Z. Larson, Robert R. Flavell, Thomas A. Hope
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-8 (2020)
Abstract Background In this study, we investigate the impact of increased PET acquisition time per bed position on lesion detectability, standard uptake value, and image noise in 68Ga-PSMA-11 PET/MRI scans. Methods Scans of twenty patients were analy
Externí odkaz:
https://doaj.org/article/013ad5673fed4615a49ec8ff28489e7a
Publikováno v:
Bioengineering, Vol 10, Iss 3, p 358 (2023)
Despite the proliferation of deep learning techniques for accelerated MRI acquisition and enhanced image reconstruction, the construction of large and diverse MRI datasets continues to pose a barrier to effective clinical translation of these technol
Externí odkaz:
https://doaj.org/article/0cf7640be5254ad1b01815982eec3e0d
Autor:
Georgios Batsios, Céline Taglang, Peng Cao, Anne Marie Gillespie, Chloé Najac, Elavarasan Subramani, David M. Wilson, Robert R. Flavell, Peder E. Z. Larson, Sabrina M. Ronen, Pavithra Viswanath
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionThe pentose phosphate pathway (PPP) is essential for NADPH generation and redox homeostasis in cancer, including glioblastomas. However, the precise contribution to redox and tumor proliferation of the second PPP enzyme 6-phosphogluconola
Externí odkaz:
https://doaj.org/article/b0ed84caf6374aad89fd39ef6cf30daa
Publikováno v:
BMC Psychology, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background Post-traumatic Stress Disorder (PTSD) is a common sequelae of severe combat-related emotional trauma that is often associated with significantly reduced quality of life in afflicted veterans. To date, no published study has examin
Externí odkaz:
https://doaj.org/article/b3928e3829884d508c4f27c52fe374f9
Autor:
Hsin‐Yu Chen, Robert A. Bok, Matthew R. Cooperberg, Hao G. Nguyen, Katsuto Shinohara, Antonio C. Westphalen, Zhen J. Wang, Michael A. Ohliger, Daniel Gebrezgiabhier, Lucas Carvajal, Jeremy W. Gordon, Peder E. Z. Larson, Rahul Aggarwal, John Kurhanewicz, Daniel B. Vigneron
Publikováno v:
Magnetic Resonance in Medicine. 88:2609-2620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f97ebd3fd4a7cf68dfb6af3642d345d4
https://doi.org/10.1002/mrm.29399
https://doi.org/10.1002/mrm.29399