Výsledky vyhledávání - "E. A. Gusakov"

Akademický článek

Evaluation of the cytotoxic activity and toxicity of a tropolone derivative with a potential antitumor effect

Autor: O. I. Kit, V. I. Minkin, E. A. Lukbanova, Yu. A. Sayapin, E. A. Gusakov, A. O. Sitkovskaya, S. Yu. Filippova, E. F. Komarova, A. V. Volkova, D. V. Khodakova, M. V. Mindar, Yu. N. Lazutin, M. A. Engibaryan, V. E. Kolesnikov

Publikováno v: Бюллетень сибирской медицины, Vol 21, Iss 2, Pp 60-66 (2022)

The aim. To study the toxicity of 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone in vitro and in vivo.Materials and methods. 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone was synthesized

Externí odkaz: https://doaj.org/article/30f94e7c9b874e1d94d06d3d95a99e9f

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Akademický článek

Study of biological activity of 2-quinoline-2-yl-derivative 1,3-tropolone in experiment

Autor: E. A. Lukbanova, E. A. Dzhenkova, A. S. Goncharova, A. Yu. Maksimov, E. F. Komarova, V. I. Minkin, Yu. A. Sayapin, E. A. Gusakov, L. Z. Kurbanova, A. A. Kiblitskaya, E. V. Zaikina, M. V. Mindar, M. V. Voloshin, A. V. Shaposhnikov, I. B. Lysenko, N. V. Nikolaeva

Publikováno v: Issledovaniâ i Praktika v Medicine, Vol 9, Iss 2, Pp 50-64 (2022)

Purpose of the study. Was to reveal the antitumor effect of 2‑(6,8‑dimethyl‑5‑nitro‑4‑chloroquinoline‑2‑yl)‑5,6,7‑trichloro‑1,3‑tropolone in subcutaneous PDX models of human lung cancer.Material and methods. The studied tropol

Externí odkaz: https://doaj.org/article/856577f4d78b4c18ab2670d440144561

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Akademický článek

Assessment of an antitumor effect of 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone in A-549 tumor cell subcutaneous xenografts

Autor: E. A. Lukbanova, E. V. Zaikina, Yu. A. Sayapin, E. A. Gusakov, S. Yu. Filippova, E. Yu. Zlatnik, A. V. Volkova, L. Z. Kurbanova, D. V. Khodakova, D. O. Kaymakchi, Ju. N. Lazutin, A. N. Shevchenko, O. V. Pandova

Publikováno v: Alʹmanah Kliničeskoj Mediciny, Vol 49, Iss 0 (2020)

Rationale: Chemotherapy is one of the lung cancer treatment methods. The search for new substances with antitumor effect against malignant lung neoplasms is relevant because of low efficacy and side effects of cytotoxic agents. A promising substance

Externí odkaz: https://doaj.org/article/156bc364cb19440caa39b11df288be29

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