Výsledky vyhledávání - "E. A. Glubokova"

Akademický článek

Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro

Autor: N. P. Kartashova, A. V. Ivanina, E. A. Glubokova, I. N. Falynskova, A. A. Poromov, I. A. Leneva

Publikováno v: Антибиотики и Химиотерапия, Vol 67, Iss 9-10, Pp 35-41 (2022)

Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before. The aim of th

Externí odkaz: https://doaj.org/article/5e1f33ca858a4d47b1e1a1acaae907b6

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Akademický článek

The study of neuraminidase immunity in protection against secondary bacterial pneumonia induced by S. aureus after influenza infection in mice

Autor: I. A. Leneva, I. N. Falynskova, N. P. Kartashova, E. A. Glubokova, A. V. Poddubikov, O. A. Svitich

Publikováno v: Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 97, Iss 6, Pp 564-577 (2021)

Introduction. Pneumonia often occurs secondary to influenza infection and accounts for a large proportion of the morbidity and mortality associated with seasonal and pandemic influenza outbreaks. We previously have shown that vaccination with Virus-l

Externí odkaz: https://doaj.org/article/b5e35603be02458b821f44099ad6c19c

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Akademický článek

Vaccination with virus-like particles containing hemagglutinin protects the lungs of mice with postifluenza bacterial pneumonia: virological, microbiological and clinical data

Autor: I. N. Falynskova, A. Yu. Egorov, A. V. Poddubikov, N. O. Vartanova, N. P. Kartashova, E. A. Glubokova, V. A. Mkhitarov, D. S. Dzhalilova, O. V. Makarova, I. A. Leneva

Publikováno v: Вопросы вирусологии, Vol 65, Iss 3, Pp 150-158 (2020)

Introduction. Influenza is a severe viral disease, a frequent complication of which is a secondary bacterial pneumonia. Influenza vaccines prevent secondary bacterial complications. Virus-like particles are one of the promising areas for the developm

Externí odkaz: https://doaj.org/article/336733994bfa484081ce9e07daabbd5a

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Akademický článek

Evaluation of the Efficacy of Riamilovir and Oseltamivir Combination on the Experimental Model of Mice Influenza Infection

Autor: I. N. Falynskova, I. A. Lenyova, O. V. Makarova, N. R. Makhmudova, E. A. Glubokova, N. P. Kartashova, V. A. Mkhitarov, D. Sh. Dzhalilova

Publikováno v: Антибиотики и Химиотерапия, Vol 62, Iss 11-12, Pp 21-28 (2020)

Riamilovir (Triazavirin®) Is an original Russian preparation of the azoloazine family, an analogue of the purine nucleoside (guanosine), it belongs to inhibitors of the synthesis of viral RNAs and replicators of genomic fragments. The drug has a wid

Externí odkaz: https://doaj.org/article/2a8148f6a0ab4d1698794436736e2626

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Akademický článek

Influenza virus infection and postviral bacterial pneumonia pathogenesis induced by different subtypes of influenza virus in mice

Autor: A. A. Poromov, N. R. Makhmudova, I. N. Falynskova, E. A. Glubokova, N. P. Kartashova, I. T. Fedyakina, O. A. Svitich, I. A. Leneva

Publikováno v: Медицинская иммунология, Vol 22, Iss 1, Pp 99-110 (2020)

Secondary bacterial infections after influenza virus infection further increase morbidity and mortality due to influenza. Despite of seasonal influenza vaccination, antiviral drugs and antibiotics are widely used in viral/bacterial pneumonia therapy.

Externí odkaz: https://doaj.org/article/de8b54f6a44a4adf9274be541b89aa58

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Akademický článek

INDUCTION OF SECONDARY BACTERIAL PNEUMONIA IN MICE INFECTED WITH PANDEMIC AND LABORATORY STRAINS OF THE H1N1 INFLUENZA VIRUS

Autor: I. A. Leneva, A. Yu. Egorov, I. N. Falynskova, N. R. Маkhmudоvа, N. P. Kartashova, E. A. Glubokova, N. O. Vartanova, A. V. Poddubikov

Publikováno v: Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 1, Iss 1, Pp 68-74 (2019)

Aim. In this study we developed and characterized a mouse model of secondary S. aureus and S. pneumoniae pneumonia following influenza virus infection with H1N1 pandemic and laboratory strains and their reassortment. Materials and methods. BALB/с mi

Externí odkaz: https://doaj.org/article/e296b1740a0f419499595bd8e24172f2

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Efficacy of an experimental drug based on technologically processed antibodies in models of influenza infection and secondary bacterial pneumonia: Results of a preclinical study

Autor: N. V. Petrova, N. P. Kartashova, S. A. Tarasov, E. A. Glubokova, A. G. Emelianova

Publikováno v: Nauchno-prakticheskii zhurnal «Patogenez». :55-63

Целью исследования была оценка противовирусной активности экспериментальных образцов сверхвысоких разведений антител к различным ми�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b877b0f5e115c2b28e7115e4374c34f1
https://doi.org/10.25557/2310-0435.2020.04.55-63

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[Generation of SARS-CoV-2 Mouse Model by Transient Expression of the Human ACE2 Gene Mediated by Intranasal Administration of AAV-hACE2]

Autor: D V, Glazkova, E V, Bogoslovskaya, F A, Urusov, N P, Kartashova, E A, Glubokova, A V, Gracheva, E B, Faizuloev, G V, Trunova, V A, Khokhlova, O A, Bezborodova, A A, Pankratov, I A, Leneva, G A, Shipulin

Publikováno v: Molekuliarnaia biologiia. 56(5)

One of the most important steps in the development of drugs and vaccines against a new coronavirus infection is their testing on a relevant animal model. The laboratory mouse, with well-studied immunology, is the preferred mammalian model in experime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fbdd4836ee37f1df45502f1e85eab568
https://pubmed.ncbi.nlm.nih.gov/36165016

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Cytotoxic cationic peptides as а ligands for receptor nucleolin

Autor: S. M. Andreev, A. A. Lushnikova, E. G. Glubokova, Alexandr Vladislavovich Kostarev, D. A. Ponkratova, A. V. Onyan

Publikováno v: Uspehi Molekulârnoj Onkologii, Vol 5, Iss 3, Pp 59-64 (2018)

Background. Chaperone proteins nucleolin (NCL, or C23) and nucleophosmin (NPM, or B23) regulate key cell functions. The most tumors are characterized by over-expression of these proteins, especially in cell nuclei and on the сell surface, as NCL. Di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc5a4bc0a6c3db9a306f3de83c0f7dc
https://doi.org/10.17650/2313-805x-2018-5-3-59-64

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