Zobrazeno 1 - 2
of 2
pro vyhledávání: '"E. A. Arasa-Verge"'
Autor:
J. Ferreira da Silva, G. P. Oliveira, E. A. Arasa-Verge, C. Kagiou, A. Moretton, G. Timelthaler, J. Jiricny, J. I. Loizou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Prime Editing is a versatile genome engineering tool. Here, the authors identify the DNA repair pathway known as mismatch repair as inhibitory for Prime Editing, thus, loss of mismatch repair enhances the efficiency of Prime Editing.
Externí odkaz:
https://doaj.org/article/c5eb288776124ca0807ead6fd587e370
Autor:
J. Ferreira da Silva, G. P. Oliveira, E. A. Arasa-Verge, C. Kagiou, A. Moretton, G. Timelthaler, J. Jiricny, J. I. Loizou
Publikováno v:
Nature Communications, 13
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Prime editing (PE) is a powerful genome engineering approach that enables the introduction of base substitutions, insertions and deletions into any given genomic locus. However, the efficiency of PE varies widely and depends not only on the genomic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460dd1ec11c0ff4ce39943f4974931dc
https://pubmed.ncbi.nlm.nih.gov/35140211
https://pubmed.ncbi.nlm.nih.gov/35140211