Zobrazeno 1 - 10
of 358
pro vyhledávání: '"E-4031"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1204 (2023)
hERG (human Ether-à-go-go Related Gene)-encoded potassium channels underlie the cardiac rapid delayed rectifier (IKr) potassium current, which is a major target for antiarrhythmic agents and diverse non-cardiac drugs linked to the drug-induced form
Externí odkaz:
https://doaj.org/article/a519a69e6fa0409bac507e4537ea4ecc
Autor:
Suchitra Matsukura, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando, Hiroshi Yamazaki, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 2, Pp 103-109 (2017)
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na+, Ca2+ and K+ channels, respectively. Intravenous
Externí odkaz:
https://doaj.org/article/2b67043284f54d62bdc345c0b7f0d62e
Publikováno v:
Micromachines, Vol 11, Iss 4, p 450 (2020)
Heart related ailments are some of the most common causes for death in the world, and some of the causes are cardiac toxicity due to drugs. Several platforms have been developed in this regard over the years that can measure electrical or mechanical
Externí odkaz:
https://doaj.org/article/b7987a5de6744050bd3f0f0f950d19c2
Akademický článek
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Publikováno v:
Micromachines, Vol 11, Iss 450, p 450 (2020)
Micromachines
Volume 11
Issue 4
Micromachines
Volume 11
Issue 4
Heart related ailments are some of the most common causes for death in the world, and some of the causes are cardiac toxicity due to drugs. Several platforms have been developed in this regard over the years that can measure electrical or mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cf12a7e35ac7122d23f7abd24e0036
https://www.mdpi.com/2072-666X/11/4/450
https://www.mdpi.com/2072-666X/11/4/450
Autor:
Keiichi Fukuda, Kazuho Sakamoto, Masahiko Yamaguchi, Mana Sugimoto, Junko Kurokawa, Masaki Ieda, Takeshi Suzuki, Shintaro Sugimoto, Fumiya Tamura
Publikováno v:
Biomolecules, Vol 11, Iss 1385, p 1385 (2021)
Biomolecules
Volume 11
Issue 9
Biomolecules
Volume 11
Issue 9
Inhibition of K+-conductance through the human ether-a-go-go related gene (hERG) channel leads to QT prolongation and is associated with cardiac arrhythmias. We previously reported that physiological concentrations of some estrogens partially suppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07c63e7422db610a6c7892b67c2a502
https://doi.org/10.3390/biom11091385
https://doi.org/10.3390/biom11091385
Akademický článek
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Autor:
Atsushi Sugiyama, Kentaro Ando, Suchitra Matsukura, Takeshi Wada, Hiroko Izumi-Nakaseko, Xin Cao, Hiroshi Yamazaki, Yuji Nakamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 2, Pp 103-109 (2017)
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na+, Ca2+ and K+ channels, respectively. Intravenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad484b585b8d22c616fba004d9c42363
http://www.sciencedirect.com/science/article/pii/S1347861317300178
http://www.sciencedirect.com/science/article/pii/S1347861317300178
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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