TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study

Autor: A. J. M. Meijer, F. A. Diepstraten, T. Langer, L. Broer, I. K. Domingo, E. Clemens, A. G. Uitterlinden, A. C. H. de Vries, M. van Grotel, W. P. Vermeij, R. A. Ozinga, H. Binder, J. Byrne, E. van Dulmen-den Broeder, M. L. Garrè, D. Grabow, P. Kaatsch, M. Kaiser, L. Kenborg, J. F. Winther, C. Rechnitzer, H. Hasle, T. Kepak, K. Kepakova, W. J. E. Tissing, A. L. F. van der Kooi, L. C. M. Kremer, J. Kruseova, S. M. F. Pluijm, C. E. Kuehni, H. J. H. van der Pal, R. Parfitt, C. Spix, A. Tillmanns, D. Deuster, P. Matulat, G. Calaminus, A. E. Hoetink, S. Elsner, J. Gebauer, R. Haupt, H. Lackner, C. Blattmann, S. J. C. M. M. Neggers, S. R. Rassekh, G. E. B. Wright, B. Brooks, A. P. Nagtegaal, B. I. Drögemöller, C. J. D. Ross, A. P. Bhavsar, A. G. am Zehnhoff-Dinnesen, B. C. Carleton, O. Zolk, M. M. van den Heuvel-Eibrink, the PanCareLIFE Consortium, and the CPNDS Consortium

Publikováno v: npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)

Abstract In children with cancer, the heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility. Using a genome-wide association study (GWAS) approach, we identified a genetic variant in TCERG1L (rs893

Externí odkaz: https://doaj.org/article/1a21ee1f4f0440f184693f4b2b482abf

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Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors

Autor: Alison Leiper, L. C. M. Kremer, Jeanette Falck Winther, James M. Byrne, Dalit Modan-Moses, M M van den Heuvel-Eibrink, Riccardo Haupt, C.B. Lambalk, Melanie Kaiser, J.W.R. Twisk, M. van den Berg, Claudia Spix, Uta Dirksen, Claire Berger, Tomáš Kepák, Jarmila Kruseova, M. van Dijk, Cécile M. Ronckers, E. van Dulmen-den Broeder, Peter Kaatsch, F.E. van Leeuwen, Desiree Grabow, A.L.F. van der Kooi, Victoria Grandage, Sophie D. Fosså

Publikováno v: PanCareLIFE Consortium 2021, ' Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors : investigating dose-effect relationships in a European case-control study (PanCareLIFE) ', Human reproduction (Oxford, England), vol. 36, no. 6, pp. 1561-1573 . https://doi.org/10.1093/humrep/deab035
Human reproduction (Oxford, England), 36(6), 1561-1573. Oxford University Press
van den Berg, M H, van Dijk, M, Byrne, J, Berger, C, Dirksen, U, Winther, J F, Fossa, S D, Grabow, D, Grandage, V L, Haupt, R, van den Heuvel-Eibrink, M M, Kaiser, M, Kepak, T, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Lambalk, C B, van Leeuwen, F E, Leiper, A, Modan-Moses, D, Spix, C, Twisk, J W R, Ronckers, C M, Kaatsch, P, van Dulmen-den Broeder, E & PanCareLIFE Consortium 2021, ' Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors : investigating dose-effect relationships in a European case-control study (PanCareLIFE) ', Human Reproduction, vol. 36, no. 6, pp. 1561-1573 . https://doi.org/10.1093/humrep/deab035

STUDY QUESTION Which chemotherapeutic agents and body site-specific radiation fields are dose-dependently associated with an increased risk of fertility impairment in long-term female childhood, adolescent and young adulthood (CAYA) cancer survivors?

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d41e6100776ef7922e69c991967087
https://pure.eur.nl/en/publications/413cab3b-347e-42bc-9dfb-feee89874cec

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