Zobrazeno 1 - 10
of 10
pro vyhledávání: '"E Yu, Kochetkova"'
Autor:
Zh. V. Shitikova, Valery A. Pospelov, N. M. Yartseva, T. V. Bykova, S. G. Zubova, E. Yu. Kochetkova, Pospelova Tv
Publikováno v:
Cell and Tissue Biology. 15:248-259
Genome instability manifested by multiple reorganization contributes to the acquisition of new properties by tumor cells, resistance to therapy in particular. Structural rearrangements of chromosomes can be induced by damage to DNA, for example, by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e6b18507669e63b228e2339cf58958
https://doi.org/10.1134/s1990519x21030135
https://doi.org/10.1134/s1990519x21030135
Publikováno v:
Cell and Tissue Biology. 14:437-447
Tumors with ocogenic Ras protein expression are hard to cure, since they are able to restore viability after treatment with antitumor agents by activating cytoprotective processes. The search for new targets for more effective therapy has shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0de55e77d2ec818fc1385c901d593fc
https://doi.org/10.1134/s1990519x20060061
https://doi.org/10.1134/s1990519x20060061
Publikováno v:
Cell and Tissue Biology. 13:344-352
Mutations and amplifications of the Ppm1d gene encoding Wip1 phosphatase have been found in various tumors. Recent studies have shown that the presence of Wip1 stable mutant after chemotherapy suggests that Wip1 is involved in the resistance of malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e63d607edac40deece4fa65117c9e3ed
https://doi.org/10.1134/s1990519x19050043
https://doi.org/10.1134/s1990519x19050043
Autor:
S. G. Zubova, E. Yu. Kochetkova, Pospelova Tv, T. V. Bykova, G. I. Blinova, Valery A. Pospelov
Publikováno v:
Cell and Tissue Biology. 11:268-274
Autophagy is a conserved process of protein and organelle degradation that serves to maintain cell viability. Autophagy is frequently induced in response to stress or to exposure to DNA-damaging agents or retinoids, as well as to starvation and defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1890df5c8ae0fab15975d6e8f976767
https://doi.org/10.1134/s1990519x1704006x
https://doi.org/10.1134/s1990519x1704006x
Publikováno v:
Cell and Tissue Biology. 10:290-296
UV irradiation is a major natural and artificial stress factor that may cause severe skin injury. UV irradiation induces DNA damage, which, eventually, may lead to cell death, senescence or oncogenic mutations and tumor growth. Wip1 is a phosphatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4696c56e56e473780301ac05f61899
https://doi.org/10.1134/s1990519x16040088
https://doi.org/10.1134/s1990519x16040088
Publikováno v:
Tsitologiia. 58(12)
Autophagy is a conservative process of misfolded protein and damaged organelle degradation that serves to support cellular viability. Autophagy is often induced in response to stress, DNA damage, retinoids, starvation and growth factor withdrawal. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26cfc47824fd49e448706cf224cab2ef
https://pubmed.ncbi.nlm.nih.gov/30188620
https://pubmed.ncbi.nlm.nih.gov/30188620
Publikováno v:
Tsitologiia. 38(12)
We have studied the dependence of cell viability on cell autophagy in control and senescent E1A+cHa-Ras transformed rat embryo fibroblasts. pp242, a TORC1/C2 kinase inhibitor, was used as a trigger of cell autophagy. Cell senescence was induced in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ab7c576d51389177be227d4df4783f59
https://pubmed.ncbi.nlm.nih.gov/30188621
https://pubmed.ncbi.nlm.nih.gov/30188621
Publikováno v:
Biopolymers and Cell. 35:212-213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6aae5955a8fba2a742480203888418e
https://doi.org/10.7124/bc.0009e1
https://doi.org/10.7124/bc.0009e1
Publikováno v:
Cell and Tissue Biology. 8:374-383
A key regulator of cellular senescence, mTORC1 complex, is a target of many signaling cascades, including Ras/Raf/MEK/ERK cascade. In this paper, we investigated the role of the MEK/ERK branch of this cascade in the process of cellular senescence ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b64403a096c04b3a60e8ad3f3f1848b
https://doi.org/10.1134/s1990519x14050034
https://doi.org/10.1134/s1990519x14050034
Publikováno v:
Cell and Tissue Biology. 7:126-135
We have studied the role of the stress kinases p38 and JNK1,2 in premature senescence induced by sodium butyrate (NaBut), a histone deacetylase inhibitor, in mouse embryonic fibroblasts transformed by E1A+cHa-Ras oncogenes. It was found that transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c60d279f7a4d856329b317ad1f19397c
https://doi.org/10.1134/s1990519x13020065
https://doi.org/10.1134/s1990519x13020065