Výsledky vyhledávání - "E Worthington"

Akademický článek

Rare mutations in the complement regulatory gene CSMD1 are associated with male and female infertility

Autor: Arthur S. Lee, Jannette Rusch, Ana C. Lima, Abul Usmani, Ni Huang, Maarja Lepamets, Katinka A. Vigh-Conrad, Ronald E. Worthington, Reedik Mägi, Xiaobo Wu, Kenneth I. Aston, John P. Atkinson, Douglas T. Carrell, Rex A. Hess, Moira K. O’Bryan, Donald F. Conrad

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

Many molecular and physiological mechanisms in the regulation of fertility are shared between female and male mammals. Here, Lee et al. report an association of CNVs in CSMD1 with early idiopathic menopause in women and show that loss of Csmd1 leads

Externí odkaz: https://doaj.org/article/60cd321fd0b3463ab76d53b0cfcb3f9d

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Image-Guided High Intensity Focused Ultrasound System for Large Animal Nerve Ablation Studies

Autor: Jahan Tavakkoli, Arthur E. Worthington, Kevin Rod, Vera Bril, Philip Peng

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine, Vol 4, Pp 1-6 (2016)
IEEE Journal of Translational Engineering in Health and Medicine

High intensity focused ultrasound (HIFU) is a form of thermal ablation technique, which can treat a variety of medical afflictions. One promising therapeutic use is the permanent destruction of nerves non-invasively in patients with severe spasticity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f15e4c1948ac5bb114a964e2b2f428f
https://doi.org/10.32920/21842484.v1

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Using High Frequency Ultrasound Envelope Statistics to Determine Scatterer Number Density in Dilute Cell Solutions

Autor: Michael Kolios, Michael D. Sherar, A. E. Worthington, A. Giles, G. J. Czarnota, Ralph E. Baddour, A. S. Tunis

It has previously been demonstrated in tissue-mimicking phantoms and in tissue that envelope statistics of US backscatter are affected by changes in the scatterer properties [1–4, 32, 37]. At higher frequencies the wavelength of the US begins to ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82e09ae55baaa88dff02fd51f575d6d
https://doi.org/10.32920/ryerson.14636748

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Towards Understanding the Nature of High Frequency Ultrasound Backscatter from Cells and Tissues: an Investigation of Backscatter Power Spectra from Different Concentrations of Cells of Different Sizes

Autor: Michael D. Sherar, A. S. Tunis, A. Giles, A. E. Worthington, G. J. Czarnota, Michael Kolios

During cell death a series of structural changes occur within the cell. We have shown that cell ensembles and tissues undergoing structural changes associated with various cell death pathways can be detected using high-frequency ultrasound. In our ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254d65d7e887263853e27f81c2cbd899
https://doi.org/10.32920/ryerson.14636697.v1

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Rare mutations in the complement regulatory gene CSMD1 are associated with male and female infertility

Autor: Abul Usmani, John P. Atkinson, Douglas T. Carrell, Moira K O'Bryan, Arthur Lee, Donald F. Conrad, Katinka A. Vigh-Conrad, Xiaobo Wu, Ronald E. Worthington, Ana C. Lima, Maarja Lepamets, Rex A. Hess, Kenneth I. Aston, Ni Huang, Jannette Rusch, Reedik Mägi

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications

Infertility in men and women is a complex genetic trait with shared biological bases between the sexes. Here, we perform a series of rare variant analyses across 73,185 women and men to identify genes that contribute to primary gonadal dysfunction. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315495513f785e5a98e98f18d5fc9140
https://doaj.org/article/60cd321fd0b3463ab76d53b0cfcb3f9d

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Correlation of Steady State and Transient Temperature Profiles in Perfused Fixed Kidneys: Implications for Thermal Models

Autor: J. W. Hunt, A. E. Worthington, Michael D. Sherar, Michael C. Kolios

1. INTRODUCTION Thermal models are used in hyperthermia to predict temperature distributions for treatment and applicator optimization. It is known that blood flow can significantly influence temperature profiles but an accurate description of this e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec30bc22d273fae755176db4a0b31b1
https://doi.org/10.32920/ryerson.14639265

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