Zobrazeno 1 - 10
of 888
pro vyhledávání: '"E Wesley, Ely"'
Autor:
L. P. Beyer, L. von zur Gathen, B. El Rayah, O. Dewald, T. Zieschang, A. Diers, E. Wesley Ely, U. Guenther
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Disorientation is an early indicator of developing postoperative delirium (POD), which is associated with increased mortality and cognitive decline. The well-established “Confusion-Assessment-Method-for-Intensive-Care-Unit” (C
Externí odkaz:
https://doaj.org/article/1a8ee29302a94a4f98381cf83eda47c9
Autor:
Carolin Fleischmann-Struzek, Sebastian Born, Miriam Kesselmeier, E. Wesley Ely, Kristin Töpfer, Heike Romeike, Michael Bauer, Sven Bercker, Ulf Bodechtel, Sandra Fiedler, Heinrich V. Groesdonk, Sirak Petros, Stefanie Platzer, Hendrik Rüddel, Torsten Schreiber, Konrad Reinhart, André Scherag
Publikováno v:
The Lancet Regional Health. Europe, Vol 46, Iss , Pp 101066- (2024)
Summary: Background: Surviving sepsis can lead to chronic physical, psychological and cognitive impairments, which affect millions of patients worldwide, including survivors after COVID-19 viral sepsis. We aimed to characterize the magnitude and traj
Externí odkaz:
https://doaj.org/article/ba8f38920d884d8da617b942097e4446
Autor:
Tuqa Alkhateeb, Joanna L. Stollings, Ine Sohn, Dandan Liu, L. Montana Fleenor, E. Wesley Ely, Shouri Lahiri
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Recent preclinical studies demonstrate a direct pathological role for the interleukin-6 (IL-6) pathway in mediating structural and functional delirium-like phenotypes in animal models of acute lung injury. Tocilizumab, an IL-6 pathway inhibi
Externí odkaz:
https://doaj.org/article/2543084245a24d0dbfc5fbd900d63fa1
Autor:
Katarzyna Kotfis, Patrycja Maj, Aleksandra Szylińska, Maria Pankowiak, Elżbieta Reszka, E. Wesley Ely, Annachiara Marra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract During intensive care unit admission, relatives of critically ill patients can experience emotional distress. The authors hypothesized that families of patients who are diagnosed with intensive care unit (ICU) delirium experience more profou
Externí odkaz:
https://doaj.org/article/2b7c8df3e7d44347adf8e41de3f9f93b
Autor:
Kelly M. Potter, Jason N. Kennedy, Chukwudi Onyemekwu, Niall T. Prendergast, Pratik P. Pandharipande, E Wesley Ely, Christopher Seymour, Timothy D. Girard
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104942- (2024)
Summary: Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subt
Externí odkaz:
https://doaj.org/article/cc520dd1c1d545d68d1c1dc5a2e0c85e
Autor:
Sonal Agrawal, Jose M. Farfel, Konstantinos Arfanakis, Lena Al-Harthi, Tanner Shull, Tara L. Teppen, Arnold M. Evia, Mayur B. Patel, E. Wesley Ely, Sue. E. Leurgans, David A. Bennett, Rupal Mehta, Julie A. Schneider
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background This study examined neuropathological findings of patients who died following hospitalization in an intensive care unit with SARS-CoV-2. Methods Data originate from 20 decedents who underwent brain autopsy followed by ex-vivo imag
Externí odkaz:
https://doaj.org/article/8ca981d6caa448c7bc691ebccb3bcd45
Autor:
Christopher G. Hughes, Christina S. Boncyk, Benjamin Fedeles, Pratik P. Pandharipande, Wencong Chen, Mayur B. Patel, Nathan E. Brummel, James C. Jackson, Rameela Raman, E. Wesley Ely, Timothy D. Girard
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-12 (2022)
Abstract Background Delirium is a frequent manifestation of acute brain dysfunction and is associated with cognitive impairment. The hypothesized mechanism of brain dysfunction during critical illness is centered on neuroinflammation, regulated in pa
Externí odkaz:
https://doaj.org/article/cb57e9307eaa44bbb76a07a485c327af
Autor:
Hirsh Makhija, MS, Janelle M. Fine, BS, Daniel Pollack, MSN, APRN, ACCNS-AG, CCRN, Francesca Novelli, MSN, RN, CCRN, Judy E. Davidson, DNP, RN, MCCM, FAAN, Shannon A. Cotton, BSN, RN, CCRN, Bianca Diaz De Leon, BS, BA, Paola Alicea Reyes, BS, Jessica L. Montoya, PhD, Carmen Mabel Arroyo-Novoa, PhD, RN, MSN, MSc, FCCM, Milagros I. Figueroa-Ramos, PhD, RN, MSN, FCCM, Yeonsu Song, PhD, RN, FNP, Ana Lucia Fuentes, MD, Jamie Nicole LaBuzetta, MD, MSc, MPhil, Alison A. Moore, MD, MPH, E. Wesley Ely, MD, MPH, Atul Malhotra, MD, Dale M. Needham, MD, PhD, Jennifer L. Martin, PhD, Biren B. Kamdar, MD, MBA, MHS
Publikováno v:
Critical Care Explorations, Vol 5, Iss 7, p e0939 (2023)
OBJECTIVES:. Although delirium detection and prevention practices are recommended in critical care guidelines, there remains a persistent lack of effective delirium education for ICU providers. To address this knowledge-practice gap, we developed an
Externí odkaz:
https://doaj.org/article/749ed5e441f449ddbe6c8d844b9b2eba
Autor:
Faizan Anwar, Nicklaus A. Sparrow, Mohammad Harun Rashid, Gena Guidry, Michael M. Gezalian, Eric J. Ley, Maya Koronyo-Hamaoui, Itai Danovitch, E. Wesley Ely, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Acute neuropsychiatric impairments occur in over 70% of patients with acute lung injury. Mechanical ventilation is a well-known precipitant of acute lung injury and is strongly associated with the development of acute delirium and anxiety ph
Externí odkaz:
https://doaj.org/article/5b0cf2ca25d24b3cb45f3271401af387
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-13 (2022)
Abstract Acute kidney injury is a known clinical risk factor for delirium, an acute cognitive dysfunction that is commonly encountered in the critically ill population. In this comprehensive review of clinical and basic research studies, we detail th
Externí odkaz:
https://doaj.org/article/e0f953460b8f4d35b864344026bab3c7