Zobrazeno 1 - 10
of 18
pro vyhledávání: '"E W N Levarht"'
Autor:
J.C. Kwekkeboom, R.A. van Schaarenburg, R. Mahdad, Rik Lories, Andreea Ioan-Facsinay, A Bakker, Silvia Monteagudo, Chahrazad Cherifi, R. Lubbers, Rem Toes, E W N Levarht, Leendert A. Trouw
Publikováno v:
Osteoarthritis and Cartilage
Osteoarthritis and Cartilage, 28(5), 675-684. ELSEVIER SCI LTD
Osteoarthritis and Cartilage, 28(5), 675-684. ELSEVIER SCI LTD
OBJECTIVE: Inflammation and innate immune responses may contribute to development and progression of Osteoarthritis (OA). Chondrocytes are the sole cell type of the articular cartilage and produce extracellular-matrix molecules. How inflammatory medi
Autor:
M. Reth, E W N Levarht, Hans Scherer, J.C. Kwekkeboom, J. W. Drijfhout, Holger Bang, Sanne Reijm, Gerrie Stoeken-Rijsbergen, Arieke S. B. Kampstra, George M.C. Janssen, P.A. van Veelen, Marco Cavallari, Corrie M. Wortel, Rem Toes, Twj Huizinga, Theresa Kissel, Rochelle D Vergroesen, Kimberly M. Bonger, Linda M. Slot
Publikováno v:
Annals of the rheumatic diseases, 79(4):216499, 472-480. BMJ Publishing Group
Annals of the Rheumatic Diseases, 79, 472-480
Annals of the Rheumatic Diseases, 79, 4, pp. 472-480
Annals of the Rheumatic Diseases, 79(4), 472-480. BMJ PUBLISHING GROUP
Annals of the rheumatic disease
Annals of the Rheumatic Diseases, 79, 472-480
Annals of the Rheumatic Diseases, 79, 4, pp. 472-480
Annals of the Rheumatic Diseases, 79(4), 472-480. BMJ PUBLISHING GROUP
Annals of the rheumatic disease
ObjectiveAutoantibodies against antigens carrying distinct post-translational modifications (PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid arthritis (RA). The relation between these anti-modified protein antib
Autor:
Harm-Jan Westra, Yonghong Li, René E. M. Toes, Twj Huizinga, Leendert A. Trouw, Nina A. Daha, Stefan Böhringer, Jeanine J. Houwing-Duistermaat, George N. Goulielmos, Gerrie Stoeken-Rijsbergen, E W N Levarht, Alexandra Zhernakova, Anja Roos, Fina A S Kurreeman, Willem Verduijn, Eli A. Stahl, Lude Franke
Publikováno v:
Clinical & Experimental Immunology; Vol 173
Clinical and Experimental Immunology, 173(1), 76-83. Wiley
Clinical and Experimental Immunology, 173(1), 76-83
Clinical & Experimental Immunology
Clinical and Experimental Immunology, 173(1), 76-83. Wiley
Clinical and Experimental Immunology, 173(1), 76-83
Clinical & Experimental Immunology
Rodent models for arthritis implicate a role for complement in disease development and progression. In humans, complement deposition has been observed in inflamed synovia of rheumatoid arthritis (RA) patients. In this study we analysed whether geneti
Autor:
Leendert A. Trouw, J. Stolk, C. van Kooten, Marije K. Verheul, Pieter S. Hiemstra, D. van der Woude, Hein W. Verspaget, René E. M. Toes, S. J. H. van Erp, Marko J.K. Mallat, A E van der Meulen-de Jong, E W N Levarht
Antibodies that target carbamylated proteins (anti-CarP antibodies) have been described as a biomarker in rheumatoid arthritis (RA).1 However, little is known about the factors that predispose to the production of anti-CarP antibodies. Carbamylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa77c5d659a435ccc9697be87ad08c8
http://hdl.handle.net/1887/117212
http://hdl.handle.net/1887/117212
Publikováno v:
Annals of the Rheumatic Diseases. 68:1011-1016
To investigate the clinical effects of rituximab treatment in relation to immunological effects of rituximab on tissue-derived B lineage cells and repopulation of circulating B cells.A total of 24 patients with rheumatoid arthritis (RA) were treated
Autor:
R. ten Cate, T H C M Reinards, E W N Levarht, Marieke H Otten, René E. M. Toes, Jing Shi, Esther P A H Hoppenreijs, P. C. E. Hissink Muller, Sylvia Kamphuis, Leendert A. Trouw, J.M. van den Berg, J. Anink, C.M. Jol-van der Zijde, M. A. J. van Rossum, Koert M. Dolman, Marco W. Schilham, M.J.D. van Tol, Tom W J Huizinga, L.W.A. van Suijlekom-Smit, Cornelia F Allaart, D. M. C. Brinkman, Y. Koopman-Keemink
Publikováno v:
Annals of the Rheumatic Diseases, 72, 12, pp. 2053-5
Annals of the Rheumatic Diseases, 72(12), 2053-2055
Annals of the Rheumatic Diseases; Vol 72
Annals of the Rheumatic Diseases, 72(12), 2053-2055. BMJ Publishing Group
Annals of the Rheumatic Diseases
Annals of the rheumatic diseases, 72(12), 2053-2055. BMJ Publishing Group
Annals of the Rheumatic Diseases, 72, 2053-5
Annals of the Rheumatic Diseases, 72(12), 2053-2055
Annals of the Rheumatic Diseases; Vol 72
Annals of the Rheumatic Diseases, 72(12), 2053-2055. BMJ Publishing Group
Annals of the Rheumatic Diseases
Annals of the rheumatic diseases, 72(12), 2053-2055. BMJ Publishing Group
Annals of the Rheumatic Diseases, 72, 2053-5
In juvenile idiopathic arthritis (JIA) patients there is a lack of markers that predict severe disease. Although anticitrullinated protein antibodies (ACPA) have contributed substantially to the understanding of rheumatoid arthritis (RA),1 their dete
Autor:
Cornelis L. Verweij, C. van Kooten, C C Reparon-Schuijt, E. W. N. Levarht, W. J. E. Van Esch, Ferdinand C. Breedveld
Publikováno v:
Clinical and Experimental Immunology. 123:496-504
SummaryRheumatoid factors (RFs) are autoantibodies directed against the Fc part of IgG. Considerable evidence exists that there are two classes of RFs, pathological and physiological. Whereas pathological RFs are associated with disease, physiologica
Autor:
Renee M.Y. Barge, M. van Oosterhout, E W N Levarht, J D Moolenburgh, J.M. van Laar, Willem E. Fibbe, R J Verburg
Publikováno v:
Annals of the Rheumatic Diseases. 64:1783-1785
Background: Immunoablative therapy combined with haematopoietic stem cell transplantation (SCT) is a possible treatment for patients with severe rheumatoid arthritis (RA). Case report: A patient with rheumatoid factor positive, progressively erosive
Autor:
Annemiek Willemze, D. van der Woude, E W N Levarht, W. Verduyn, R.E.M. Toes, T.W.J. Huizinga, J. Houwing, Wendimagegn Ghidey Alemayehu, Leendert A. Trouw, Gerrie Stoeken-Rijsbergen, R. R. P. De Vries
Objective Recent data suggest that a gene-environment interaction exists between smoking and the HLA SE alleles in shaping the autoimmune reaction towards specific citrullinated antigens. Here, we determined the effects of HLA SE alleles and TE (toba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee77b5d2f4469e6ca5090febaf26545
https://hdl.handle.net/1887/117786
https://hdl.handle.net/1887/117786
Autor:
Leendert A. Trouw, René E. M. Toes, E W N Levarht, E. M. Haisma, D. van der Woude, Twj Huizinga, Mohamed R. Daha, Andreea Ioan-Facsinay
Publikováno v:
Arthritis and rheumatism. 60(7)
Objective It has been suggested that anti–citrullinated protein antibodies (ACPAs) play an important role in the pathogenesis of rheumatoid arthritis (RA). To exert their pathologic effects, ACPAs must recruit immune effector mechanisms such as act