Zobrazeno 1 - 10
of 68
pro vyhledávání: '"E W, St Clair"'
Autor:
Nishant Gupta, Augustine S. Lee, Donald E. Thomas, K. Ussavarungsi, Nancy L. Carteron, E W St Clair, Richard T. Meehan, K. Dunleavy, Katherine M. Hammitt, H. Scofield, Steven E. Carsons, Teng Moua
Publikováno v:
B34. ILD CELLULAR MECHANISMS.
Autor:
Cornelis Kallenberg, Steven R. Ytterberg, Carol A. Langford, Amber M. Hummel, Paul A. Monach, E W St Clair, Peter A. Merkel, Robert Spiera, John H. Stone, Philip Seo, Fernando C. Fervenza, Jeremy Clain, Ulrich Specks, W. J. McCune, Gary S. Hoffman
Publikováno v:
Clinical and Experimental Immunology, 188(1), 174-181. Wiley
Summary Anti-neutrophil cytoplasmic antibodies (ANCA) appear to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). However, ANCA alone are not sufficient to generate disease, and some evidence suggests that infectious tri
Autor:
Paul A. Monach, Divi Cornec, E W St Clair, Eva M. Carmona, J.-O. Pers, Carol A. Langford, Tobias Peikert, Ulrich Specks, Philip Seo, Amber M. Hummel, Alvise Berti, Kristina M. Harris, Sophie Hillion, Robert Spiera, John H. Stone, Peter A. Merkel, Fernando C. Fervenza
Publikováno v:
Annals of the Rheumatic Diseases. 79:233.1-233
Background:Proteinase 3 (PR3)-reactive B cells are present in PR3-ANCA-associated vasculitis (AAV) at levels higher than healthy controls.Objectives:To evaluate the dynamics of the PR3-reactive B cell repopulation in patients with PR3-AAV after treat
Autor:
Alfred Mahr, Peter A. Merkel, Ulrich Specks, Philippe Guilpain, Solange Gonzalez-Chiappe, Paul A. Monach, E W St Clair, Sophie Edouard, Carol A. Langford, John H. Stone, D. Rauolt, P. Y. Lévy, Cornelia M. Weyand, Robert Spiera, Philip Seo, Divi Cornec, Jörg J. Goronzy
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2020, 79 (Suppl 1), pp.384.1-384. ⟨10.1136/annrheumdis-2020-eular.3361⟩
Annals of the Rheumatic Diseases, 2020, 79 (Suppl 1), pp.384.1-384. ⟨10.1136/annrheumdis-2020-eular.3361⟩
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2020, 79 (Suppl 1), pp.384.1-384. ⟨10.1136/annrheumdis-2020-eular.3361⟩
Annals of the Rheumatic Diseases, 2020, 79 (Suppl 1), pp.384.1-384. ⟨10.1136/annrheumdis-2020-eular.3361⟩
Background:Bartonellosis is an emerging anthropozoonosis caused by infection with intracellular Gram-negativeBartonellaspecies. It leads to necrotizing granulomas and endothelial damage and causes acute and chronic human diseases, such as cat scratch
Autor:
C. G. M. Kallenberg, Paul A. Monach, Gary S. Hoffman, E W St Clair, M. Villareal, Fernando C. Fervenza, Robert Spiera, Eli M. Miloslavsky, Linna Ding, Carol A. Langford, Noha Lim, Paul Brunetta, John H. Stone, Peter A. Merkel, Ulrich Specks, Philip Seo, N. K. Tchao, David Ikle
Publikováno v:
Arthritis & Rheumatology. 67:1629-1636
Objective. Nonsevere relapses are more common than severe relapses in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but their clinical course and treatment outcomes remain largely unexamined. We undertook this study to analy
Rituximab for the Treatment of Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Autor:
Brett Jepson, Steven R. Ytterberg, Peter A. Merkel, Philip Seo, Eli M. Miloslavsky, David Ikle, Coen A. Stegeman, N. K. Tchao, Carol A. Langford, Paul A. Monach, E W St Clair, Tobias Peikert, Linna Ding, Lisa Viviano, Eugene Y. Kissin, Ulrich Specks, John H. Stone, Nancy B. Allen, C. G. M. Kallenberg, Robert Spiera, Karina A. Keogh, Gary S. Hoffman, Paul Brunetta, Duvuru Geetha, M. Villarreal, Fernando C. Fervenza
Publikováno v:
Arthritis & Rheumatology. 66:3151-3159
Introduction Disease relapses are frequent in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). We evaluated the outcomes of patients re-treated with rituximab (RTX) and prednisone for severe disease relapses.
Autor:
Paul A. Monach, E W St Clair, Paul Brunetta, Eugene Y. Kissin, Steven R. Ytterberg, Philip Seo, Brett Jepson, Coen A. Stegeman, Peter A. Merkel, Gary S. Hoffman, Fernando C. Fervenza, Robert Spiera, David Ikle, Tobias Peikert, Linna Ding, Duvuru Geetha, N. K. Tchao, Cees G. M. Kallenberg, Eli M. Miloslavsky, Lisa Viviano, Carol A. Langford, Karina A. Keogh, Lourdes P. Sejismundo, Nancy B. Allen, John H. Stone, Mark Mueller, Kathleen Mieras, Ulrich Specks
Publikováno v:
Arthritis & Rheumatism. 65:2441-2449
Objective. To evaluate the reasons that complete remission is not achieved or maintained with original treatment in some patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) treated with rituximab (RTX) or with cycloph
Autor:
E W St Clair, Edward L. Treadwell, Gary S. Gilkeson, Christine G. Parks, Mary Anne Dooley, Glinda S. Cooper, Lori L. Hudson, Janardan P. Pandey
Publikováno v:
Arthritis & Rheumatism. 52:1148-1159
Objective Epstein-Barr virus (EBV) is hypothesized to play a role in the development of systemic lupus erythematosus (SLE). Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) is important in regulating T cell–mediated immunity, encompassing the
Autor:
J. R. Kalden, E W St Clair, Ravinder Nath Maini, F. C. Breedveld, Josef S Smolen, Paul A. Marsters, D. van der Heijde, Gregory Keenan, Peter E. Lipsky, Daniel E. Furst, Michael H. Weisman
Publikováno v:
Arthritis & Rheumatism. 50:1051-1065
Objective To evaluate the efficacy and safety of repeated administration of infliximab plus methotrexate (MTX) over a 2-year period in patients with rheumatoid arthritis (RA) who previously experienced an incomplete response to MTX. Methods Four hund
Autor:
Gary S. Gilkeson, Edward L. Treadwell, E W St Clair, Mary Anne Dooley, Christine G. Parks, Janardan P. Pandey, Glinda S. Cooper
Publikováno v:
Annals of the Rheumatic Diseases. 63:91-94
Background: Interleukin (IL)1α and IL1β, and their endogenous receptor antagonist (IL1Ra), have been related to the pathology of systemic lupus erythematosus (SLE), but the role of IL1 polymorphisms in the aetiology of SLE is unknown. Objective: To