Zobrazeno 1 - 8
of 8
pro vyhledávání: '"E W, Levarht"'
Autor:
Sanne Reijm, Theresa Kissel, Gerrie Stoeken-Rijsbergen, Linda M. Slot, Corrie M. Wortel, Hugo J. van Dooren, Nivine E. W. Levarht, Arieke S. B. Kampstra, Veerle F. A. M. Derksen, Pleuni Ooijevaar-de Heer, Holger Bang, Jan W. Drijfhout, Leendert A. Trouw, Tom W. J. Huizinga, Theo Rispens, Hans U. Scherer, René E. M. Toes
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modificati
Externí odkaz:
https://doaj.org/article/63a2b8cb09d24e27bf69a399f673442e
Autor:
Veerle F. A. M. Derksen, Theo Rispens, Holger Bang, Jan W. Drijfhout, Pleuni Ooijevaar-de Heer, Sanne Reijm, René E. M. Toes, Nivine E. W. Levarht, Hans Scherer, Leendert A. Trouw, Gerrie Stoeken-Rijsbergen, Corrie M. Wortel, Tom W J Huizinga, Linda M. Slot, Hugo J. van Dooren, Arieke S. B. Kampstra, Theresa Kissel
Publikováno v:
Arthritis Research and Therapy, 23(1). BMC
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Background Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1502e82abff52ec3d8523d897b4f25
https://hdl.handle.net/1887/3240261
https://hdl.handle.net/1887/3240261
Autor:
Tom W J Huizinga, Leendert A. Trouw, Rachel Knevel, Annette H M van der Helm-van Mil, Parawee Suwannalai, Anthony Cerami, René E. M. Toes, Michael P M van der Linden, George M.C. Janssen, Peter A. van Veelen, Nivine E. W. Levarht, Jing Shi
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 108
Proceedings of the National Academy of Sciences, 108(42), 17372-7
Proceedings of the National Academy of Sciences, 108(42), 17372-7
Autoimmune responses against posttranslationally modified antigens are a hallmark of several autoimmune diseases. For example, antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the prognosis and diagnosis of rheu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cdd4803d4c6ace7fdc100e2dbf8172
https://doi.org/10.1073/pnas.1114465108
https://doi.org/10.1073/pnas.1114465108
Autor:
Angela Leow, Nivine E. W. Levarht, Cornelis L. Verweij, Ellen A. M. van der Voort, Madelon M. Maurice, Ferdinand C. Breedveld
Publikováno v:
European Journal of Immunology. 28:1554-1562
In rheumatoid arthritis (RA), T cells in the inflamed joint are considered to play a crucial role in the pathogenesis. However, despite the fact that synovial T cells have an activated memory phenotype, they are functionally suppressed upon combined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138facd7df4cd242917821fbade55e4f
https://doi.org/10.1002/(sici)1521-4141(199805)28:05<1554::aid-immu1554>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199805)28:05<1554::aid-immu1554>3.0.co
Autor:
L van Dreunen, John D. Isaacs, Frederique Ponchel, J.M. van Laar, Roelof Flierman, R J Verburg, Mick M. Welling, Jacob K. Sont, René E. M. Toes, E W Levarht
Publikováno v:
Annals of the rheumatic diseases. 64(10)
Objective: To determine clinical and immunological correlates of high dose chemotherapy (HDC) + autologous stem cell transplantation (ASCT) in patients with severe rheumatoid arthritis (RA), refractory to conventional treatment. Methods: Serial sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cc6f2396eed1a1aadd9c831762ba2a
https://pubmed.ncbi.nlm.nih.gov/15829573
https://pubmed.ncbi.nlm.nih.gov/15829573
Autor:
C C, Reparon-Schuijt, W J, van Esch, C, van Kooten, N P, Ezendam, E W, Levarht, F C, Breedveld, C L, Verweij
Publikováno v:
Arthritis and rheumatism. 44(9)
To provide a comprehensive understanding of the humoral immune response that takes place at the site of inflammation in rheumatoid arthritis (RA), we studied the functional properties of synovial B cells. In particular, the response to various modes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a276dd5db5e9fd66c9234172e1dd774b
https://pubmed.ncbi.nlm.nih.gov/11592364
https://pubmed.ncbi.nlm.nih.gov/11592364
Autor:
C C, Reparon-Schuijt, W J, van Esch, C, van Kooten, B C, Rozier, E W, Levarht, F C, Breedveld, C L, Verweij
Publikováno v:
Arthritis and rheumatism. 43(5)
B lymphocytes accumulate in the inflamed joints of patients with rheumatoid arthritis (RA) and are responsible for production of high amounts of (auto)-antibodies. The aim of this study was to determine the capacity of fibroblast-like synoviocytes (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3058efe8eba0a7586fde8579b6a3800e
https://pubmed.ncbi.nlm.nih.gov/10817566
https://pubmed.ncbi.nlm.nih.gov/10817566
Autor:
C C, Reparon-Schuijt, W J, van Esch, C, van Kooten, E W, Levarht, F C, Breedveld, C L, Verweij
Publikováno v:
Arthritis and rheumatism. 41(12)
To understand the regulation of rheumatoid factor (RF) production in rheumatoid arthritis (RA), we studied IgM-RF production by B cells isolated from the synovial fluid (SF).Highly purified SF and peripheral blood (PB) B cells were isolated by negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ee9a53ec3a05309d817403428189531
https://pubmed.ncbi.nlm.nih.gov/9870878
https://pubmed.ncbi.nlm.nih.gov/9870878