Zobrazeno 1 - 10
of 58
pro vyhledávání: '"E V Chetina"'
PREDICTION OF THE COURSE OF OSTEOARTHROSIS FROM mTOR (MAMMALIAN TARGET OF RAPAMYCIN) GENE EXPRESSION
Autor:
E V Chetina, E A Bratygina, E M Zaitseva, E P Sharapova, L A Semenova, N A Demin, L I Alekseyeva, S I Glukhova, V V Kolomatsky, M A Makarov, A L Logunov, A A Roskidailo, S A Makarov
Publikováno v:
Научно-практическая ревматология, Vol 50, Iss 1, Pp 27-32 (2012)
Objective: To study whether the course of the disease can be predicted in patients with osteoarthrosis (OA), by monitoring mTOR (Mammalian Target Of Rapamycin) gene expression in their blood. Material and methods. The investigation was conducted on t
Externí odkaz:
https://doaj.org/article/0903b6f8b4314a9faedcfc5bc7f8680f
Publikováno v:
Научно-практическая ревматология, Vol 49, Iss 4, Pp 24-30 (2011)
Objective: to assess disease severity in relation to the expression of cell-division cycle genes: p21, a cyclin-dependent kinase inhibitor; caspase 3, an apoptotic activity indicator; mammalian target of rapamycin (mTOR), a major regulator of cell gr
Externí odkaz:
https://doaj.org/article/3c1aba0771e041ccaefd205328cebc26
Autor:
V A Myakotkin, M Yu Krylov, I A Guseva, E V Chetina, N V Toroptsova, O A Nikitinskaya, E Yu Samarkina, L I Benevolenskaya
Publikováno v:
Научно-практическая ревматология, Vol 49, Iss 2, Pp 15-20 (2011)
Polymorphisms of 21 genes involved in the processes of bone remodeling were studied on samples of 150 to 265 postmenopausal healthy women in a control group and those of 175 to 269 patients with osteoporosis (OP). In a Moscow sample of postmenopausal
Externí odkaz:
https://doaj.org/article/0b55568ba9cd444088f487742a20e939
Publikováno v:
Научно-практическая ревматология, Vol 47, Iss 3, Pp 18-24 (2009)
Prostaglandin E2 role in inhibition of articular cartilage collagen degradation in patients with osteoarthritis. Objective. To assess prostaglandin E2 (PGE2) role in inhibition of type II collagen digestion in explants of articular cartilage of pts w
Externí odkaz:
https://doaj.org/article/4f978085fd18444ea1f6e7b02646deef
Publikováno v:
Modern Rheumatology Journal. 17:38-44
Publikováno v:
Modern Rheumatology Journal. 16:22-27
The effectiveness of personalized therapy for rheumatoid arthritis (RA) is associated with the correct choice of the drug and the ability to predict its effect before starting the treatment.Objective: to study in patients with RA the relationship bet
Autor:
E. V. Chetina, K. E. Glemba, G. A. Markova, E. A. Naryshkin, E. A. Taskina, M. A. Makarov, A. M. Lila
Publikováno v:
Modern Rheumatology Journal. 16:42-49
About 10–40% of patients with osteoarthritis (OA) are not satisfied with the results of total arthroplasty (TA) of large joints. At the same time, the most common complication associated with the ineffectiveness of TA is postoperative pain (PP).Obj
Publikováno v:
Modern Rheumatology Journal. 16:46-51
Objective: to search for an association between basal expression of the AMP-activated protein kinase (adenosine monophosphate-activated protein kinase, AMPK) gene in the blood of patients with rheumatoid arthritis (RA) and disease activity, as well a
Publikováno v:
Современная ревматология, Vol 15, Iss 5, Pp 12-17 (2021)
Objective: to evaluate the expression of interferon-stimulated genes (ISG) – interferon (IFN) signature – in patients with rheumatoid arthritis (RA) and its dynamics during anti-B-cell therapy.Patients and methods.We examined 20 patients with RA
Publikováno v:
Современная ревматология, Vol 15, Iss 4, Pp 7-12 (2021)
Osteoarthritis (OA) is the most common disease of the elderly, which is accompanied by pain and damages all tissues of the joint. OA is associated with progressive loss of articular cartilage, sclerotic changes in the subchondral bone and the formati