Zobrazeno 1 - 10
of 21
pro vyhledávání: '"E V, Snezhkov"'
Autor:
S. B. Akopov, E. V. Snezhkov, M. V. Konovalova, M. A. Kostromina, R. S. Esipov, E. V. Svirshchevskaya
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1099-1106 (2024)
Animal tumor models are used for preclinical studies of drugs and cancer therapy. The aim of this work was to analyze the growth of murine pancreatic tumor cells Pan02, carrying GFP marker, injected subcutaneously (s. c.), intraperitoneally (i. p.) o
Externí odkaz:
https://doaj.org/article/a1d3227b956b4e9d9334eea413e25392
Publikováno v:
Acta naturae. 14(3)
The family of genes containing C2H2 zinc finger domains, which has more than 700 members, is one of the largest in the genome. Of particular interest are C2H2 genes with potential tissue-specific transcription, which determine the functional properti
Publikováno v:
Molecular Genetics, Microbiology and Virology. 34:220-227
One of the most popular nonviral delivery systems for gene therapy constructs are carriers based on polyethylenimine (PEI) DNA complexes. A number of disadvantages associated with the lack of targeted delivery and increased cytotoxicity are overcome
SOX9 as One of the Central Units of Regulation Axis of Pancreas Embryogenesis and Cancer Progression
Publikováno v:
Molecular Genetics, Microbiology and Virology. 34:159-169
The embryonic development of all body systems is controlled by coordinated interactions of a group of genes encoding master regulators of development, which determine the fate of cells in the process of differentiation. These genes are often involved
Publikováno v:
Russian Journal of Genetics. 55:523-534
The emergence of genetic diseases and evolutionary processes are associated with the flow of genetic information from one generation to another, in which genetic information carried by gametes can be changed by the appearance of de novo germline muta
Autor:
O. B. Filyukova, V. V. Pleshkan, E. V. Snezhkov, Eugene D. Sverdlov, A. V. Sass, I. V. Alekseenko
Publikováno v:
Doklady Biochemistry and Biophysics. 480:158-161
An artificial double tandem tumor-specific promoter based on survivin and human telomerase reverse transcriptase gene promoters was constructed. Studies in in vitro and ex vivo therapeutic systems showed that the designed promoter exhibits a high act
Autor:
E. V. Snezhkov, Galina S. Monastyrskaya, Eugene D. Sverdlov, I. V. Alekseenko, A. I. Kuzmich, V. V. Pleshkan, D. A. Didych
Publikováno v:
Russian Journal of Genetics. 52:650-663
The review discusses the causes of multiple failures in cancer treatment, which might primarily result from the excessive variability of cancer genomes. They are capable of changing their spatial and temporal architecture during tumor development. Th
Autor:
I V, Alekseenko, V V, Pleshkan, G S, Monastyrskaya, A I, Kuzmich, E V, Snezhkov, D A, Didych, E D, Sverdlov
Publikováno v:
Genetika. 52(7)
The review discusses the causes of multiple failures in cancer treatment, which might primarily result from the excessive variability of cancer genomes. They are capable of changing their spatial and temporal architecture during tumor development. Th
Publikováno v:
Russian Journal of Bioorganic Chemistry. 36:708-712
The content of the J peptide of secretory polymeric immunoglobulins can significantly change during various pathologies, reflecting the state of the adaptive immune system. In this study, the content of J peptide was determined in various tissues of
Autor:
D. V. Kuzmin, E. V. Snezhkov, M. I. Shakhparonov, N. V. Antipova, M. V. Zinovyeva, Ruslan I. Dmitriev, Eugene D. Sverdlov, D. K. Slizhikova, L. L. Zavalova
Publikováno v:
Molecular Biology. 41:594-600
Secreted polymeric immunoglobulins, IgA dimers and IgM pentamers, are unique in having not only the L and H chains but also the J chain, which is responsible for oligomerization. These antibodies belong to the local adaptive immune system, located in