Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E V, Navolotskaia"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 74(6)
Peptide CH3CO-Lys-Lys-Arg-Arg-NH2 (protectin) was synthesized and its activity was studied on the model of experimental myocardial infarction in rats in comparison to the reference antihypoxant drug riboxin. Intranasal injections ofprotectin at doses
Publikováno v:
Bioorganicheskaia khimiia. 36(5)
We have synthesized the peptide TPLVTLFK corresponding to the β-endorphin fragment 12-19 (the name given by the authors - octarphin), and its analogs (LPLVTLFK, TLLVTLFK, TPLVLLFK, TPLVTLLK, TPLVTLFL). The peptide octarphin was labeled with tritium
Publikováno v:
Bioorganicheskaia khimiia. 35(4)
The CH3CO-Lys-Lys-Arg-Arg-NH2 peptide (the author has named it protectin) was synthesized, and its activity was studied during different stress actions. Protectin was found to normalize the content of corticosterone and adrenalin in adrenal glands an
Autor:
Iu A, Kovalitskaia, A A, Kolobov, E A, Kampe-Nemm, V V, Iurovskií, V B, Sadovnikov, V M, Lipkin, E V, Navolotskaia
Publikováno v:
Bioorganicheskaia khimiia. 34(1)
Tritium-labeled synthetic fragments of human adrenocorticotropic hormone (ACTH) [3H]ACTH (11-24) and [3H]ACTH (15-18) with a specific activity of 22 and 26 Ci/mmol, respectively, were obtained. It was found that [3H]ACTH (11-24) binds to membranes of
Autor:
Iu A, Kovalitskaia, V B, Sadovnikov, A A, Kolobov, Iu A, Zolotarev, V V, Iurovskií, V M, Lipkin, E V, Navolotskaia
Publikováno v:
Bioorganicheskaia khimiia. 34(1)
The tritium-labeled selective agonist of the nonopioid beta-endorphin receptor the decapeptide immunorphin ([3H]SLTCLVKGFY) with a specific activity of 24 Ci/mmol was prepared. It was shown that [3H]immunorphin binds with a high affinity to the non-o
Autor:
E V, Navolotskaia, V I, Vanina, T A, Zargarova, E N, Goncharenko, N Iu, Kudriashova, M Ia, Akhalaia, V B, Sadovnikov, S G, Semushkina, A A, Kolobov, E A, Kampe-Nemm, V V, Iurovskiĭ, V M, Lipkin
Publikováno v:
Bioorganicheskaia khimiia. 30(4)
The effect of immunocortin, an ACTH-like decapeptide VKKPGSSVKV corresponding to the 11-20 sequence of the variable part of the human IgG1 heavy chain on the content of 11-hydroxycorticosteroids (CS) in rat adrenal glands and blood serum in vivo was
Autor:
N Iu, Sakharova, I A, Kostanian, T N, Lepikhova, K A, Lepikhov, A M, Malashenko, E V, Navolotskaia, J, Tombran-Tink, V M, Lipkin
Publikováno v:
Ontogenez. 33(3)
We studied the effect of synthetic peptides PEDF-6 and HLDF-6 on preimplantation development of mouse embryos in vitro. PEDF-6 peptide corresponds to fragment 351-356 and of pigment epithelium-derived differentiation factor (PEDF), while HLDF-6 pepti
Autor:
E V, Navolotskaia, N V, Malkova, T N, Lepikhova, S B, Krasnova, T A, Zargarova, V P, Zav'ialov, V M, Lipkin
Publikováno v:
Bioorganicheskaia khimiia. 27(5)
The synthetic peptide SLTCLVKGFY, corresponding to the 364-373 amino acid sequence of the human IgG heavy chain (Immunorphin), was found to compete with [125I] beta-endorphin for binding by high-affinity receptors on T lymphocytes isolated from the b
Autor:
I A, Kostanian, M V, Astapova, E V, Navolotskaia, T N, Lepikhova, S M, Dranitsyna, G B, Telegin, I L, Rodionov, L K, Baĭdakova, Iu A, Zolotarev, I M, Molotkovskaia, V M, Lipkin
Publikováno v:
Bioorganicheskaia khimiia. 26(7)
Six-membered peptide fragment TGENHR (HLDF-6) was identified in the HL-60 cell culture of human promyelocyte leukemia treated with retinoic acid when studying the differentiation factor HLDF of this cell line. HLDF-6 retains the ability of the full-s
Autor:
E V, Navolotskaia, T A, Zargarova, T N, Lepikhova, V L, Turobov, R I, Nurieva, N V, Malkova, V P, Zav'ialov, V M, Lipkin
Publikováno v:
Bioorganicheskaia khimiia. 26(1)
The antiproliferative and immunosuppressive in vitro effects of immunocortin, a synthetic adrenocorticotropin-like (ACTH-like) decapeptide H-Val-Lys-Lys-Pro-Gly-Ser-Ser-Val-Lys-Val-OH, whose sequence corresponds to segment 11-20 of the variable part