Zobrazeno 1 - 10
of 15
pro vyhledávání: '"E V, Lugovskoĭ"'
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 81(2)
New data which reveal rational approaches for pharmacologic control of blood coagulation process and confirm the key role of thrombin in haemostasis processes compared with other proteinases are presented in the review. Modulation of thrombin propert
Autor:
E V, Lugovskoĭ, I N, Kolesnikova, N E, Lugovskaia, P G, Gritsenko, L M, Litvinova, G K, Gogolinskaia, E D, Liashko, E P, Kostiuchenko, V Ia, Golota, V V, Kurochka, S V, Komisarenko
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 78(4)
ELISA for soluble fibrin (SF) quantification has been elaborated on the basis of our fibrin-specific monoclonal antibodies (mAb). Epitope for these mAb is localized in fibrin fragment Bbeta118-134. The method was used on the blood plasma of healthy p
Autor:
E V, Lugovskoĭ, I N, Kolesnikova, N E, Lugovskaia, L M, Litvinova, P G, Gritsenko, G K, Gogolinskaia, E D, Liashko, E P, Kostiuchenko, G A, Remizovskiĭ, V N, Pedchenko, S V, Komisarenko
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 76(6)
The method of D-dimer quantification in the human blood plasma has been developed using monoclonal antibodies 111-3b and II-4d. The method has been verified on the blood plasma of the patients with ischemic heart disease with and without stenocardia
Autor:
E V, Lugovskoĭ, S V, Komisarenko
Publikováno v:
Bioorganicheskaia khimiia. 26(12)
Examples of using monoclonal antibodies (MAb) for studying the fibrin polymerization mechanism are considered. MAb with epitopes situated in the fibrin polymerization sites or in the recognition sites of enzymes thrombin, plasminogen, and factor XIII
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 68(6)
Fibrinogen takes part in a lot of physiological and pathological processes in the organism. Its most important function consists in preventing blood leakage through the injured wall of the blood vessel. Proteolytic enzyme thrombin generated in the si
Autor:
V S, Chudnovets, E V, Lugovskoĭ, G K, Gogolinskaia, S G, Derzskaia, I V, Nazimov, S V, Komissarenko
Publikováno v:
Doklady Akademii nauk SSSR. 317(6)
Publikováno v:
Gematologiia i transfuziologiia. 35(7)
Addition of purified fibrin-monomer in a concentration of 0.5 mg/ml induces aggregation in a suspension of washed rat platelets in the absence of aggregants. Maximum aggregation takes place 1-3 min after fibrin-monomer addition, and then the disaggre
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal. 48(6)
The electrophoretic and NH2-terminal analyses were performed for D and E fragments obtained by tryptic digestion of bovine fibrinogen and fibrin under various conditions. The preparations of fragment D were heterogeneous, they were separated by polya
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 55(3)
Intermediate fibrin polymers formed from fibrinogen at low thrombin concentrations under physiological conditions are studied for their stability. Smith's statement that intermediate fibrin oligomers are inert molecules whose further self-assembly is
Publikováno v:
Biokhimiia (Moscow, Russia). 50(8)
The inhibitory effect of fibrinogen in the clotting of two fibrin monomer species--f-desAA and f-desAABB--was studied. The concentration dependence of this effect for two fibrin forms was found to be of the same character. This fact indicates that th