Výsledky vyhledávání - "E V, Connell"

Kinetic interaction of human immunodeficiency virus type 1 reverse transcriptase with the antiviral tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepine-2-(1H)-thione compound, R82150

Autor: E V Connell, G J Noll, K B Frank, Iain S. Sim

Publikováno v: Journal of Biological Chemistry. 266:14232-14236

We examined the kinetic interaction of purified recombinant DNA-derived human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with R82150, a member of the tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thione family of compounds (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea4b5dacf7a21cd471a0c46b54d06d44
https://doi.org/10.1016/s0021-9258(18)98672-2

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Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor

Autor: E. V. Connell, Douglas D. Richman, Ming-Chu Hsu

Combinations of the human immunodeficiency virus (HIV) Tat protein antagonist Ro 24-7429 with either the HIV protease inhibitor Ro 31-8959 or the HIV reverse transcriptase inhibitors AZT (3'-azido-3'-deoxythymidine), ddC (2',3'-dideoxycytidine), ddI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3467b6b3adf5e485ba0d645a65191a
https://europepmc.org/articles/PMC284453/

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Kinetic interaction of human immunodeficiency virus type 1 reverse transcriptase with the antiviral tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepine-2-(1H)-thione compound, R82150

Autor: K B, Frank, G J, Noll, E V, Connell, I S, Sim

Publikováno v: The Journal of biological chemistry. 266(22)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90be5a2fdb23ad3eee8a1eb8a1d9b025
https://pubmed.ncbi.nlm.nih.gov/1713579

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Discovery of a Drug Lead Employing a Peptide Library: Inhibition of HIV-1 Tat and Viral Replication by the Tripeptide YPG-NH2

Autor: E. V. Connell, M.-C. Hsu, T.-N. Huang, R. C. West, A. D. Schutt, D. L. Coffen, S. E. Ramer

Publikováno v: Antiviral Chemistry and Chemotherapy. 5:128-129

A library of the 8000 tripeptides derivable from coded amino acids was prepared in 20 sets of 400 using solid phase synthesis on a benzhydrylamine resin. The peptide mixtures, as C-terminal amides, were screened for inhibition of secreted alkaline ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ae1021f45c99efc64a06f51bd266757
https://doi.org/10.1177/095632029400500210

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Arenavirus Concentration by Molecular Filtration

Autor: G. A. Eddy, E. V. Connell, J. D. Gangemi, B. G. Mahlandt

Publikováno v: Applied and Environmental Microbiology. 34:330-332

Liter volumes of a human arenavirus pathogen (Machupo) and a nonpathogen (Tacaribe) were concentrated 30 to 100 times in less than 90 min without significant loss of particle infectivity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec942b69245981146b22335083c70085
https://doi.org/10.1128/aem.34.3.330-332.1977

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Structural polypeptides of Machupo virus

Autor: Rosato Rr, J. D. Gangemi, Johnson Em, G. A. Eddy, E. V. Connell

Publikováno v: The Journal of general virology. 41(1)

Summary The structural proteins of an arenavirus pathogen, Machupo virus, were compared to the structural proteins of two previously characterized non-pathogenic arenaviruses, Pichinde and Tacaribe, in SDS-polyacrylamide gels. Similarities in mol. wt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b30b33cf9f38ad5d11cf23f0b6ba64a
https://pubmed.ncbi.nlm.nih.gov/212518

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Synergistic activity of combinations of recombinant human alpha interferon and acyclovir, administered concomitantly and in sequence, against a lethal herpes simplex virus type 1 infection in mice

Autor: P W Trown, E V Connell, R L Cerruti

The nucleoside analog acyclovir [9-(2-hydroxyethoxymethyl)guanine] and the hybrid recombinant human alpha interferon (rHuIFN-alpha A/D) were evaluated in weanling mice for their efficacy alone and in combination against a lethal systemic infection wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2c579d82d9d4613bc12f06e5fe483d
https://europepmc.org/articles/PMC176298/

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