Zobrazeno 1 - 10
of 83
pro vyhledávání: '"E V, Chandrasekaran"'
Diabetes is a widely existing disease in patients at risk of pancreatic cancer. It originates from pancreatic endocrine gland whereas pancreatic cancer develops from exocrine glands. Leukocyte cell surface glycans are involved in leukocyte-endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba8fd02d5a0c69477f4355ad6906256
Autor:
Wiam Bshara, Shilpa A. Patil, Carl Morrison, E. V. Chandrasekaran, Sriram Neelamegham, Khushi L. Matta
Publikováno v:
Glycoconjugate Journal. 31:509-521
Glycan structure alterations during cancer regulate disease progression and represent clinical biomarkers. The study determined the degree to which changes in glycosyltransferase activities during cancer can be related to aberrant cell-surface tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80186adf64f70e2beec1b00e558d45c
https://doi.org/10.1007/s10719-014-9548-4
https://doi.org/10.1007/s10719-014-9548-4
Autor:
Conrad F. Piskorz, Jie Xia, Siraj D. Khaja, Khushi L. Matta, Sriram Neelamegham, E. V. Chandrasekaran, Robert D. Locke, Jun Xue
Publikováno v:
Glycoconjugate journal. 33(5)
Plant lectins through their multivalent quaternary structures bind intrinsically flexible oligosaccharides. They recognize fine structural differences in carbohydrates and interact with different sequences in mucin core 2 or complex-type N-glycan cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0d596b318dab448eaef68dfe4759fb
https://pubmed.ncbi.nlm.nih.gov/27318477
https://pubmed.ncbi.nlm.nih.gov/27318477
Autor:
Khushi L. Matta, Shilpa A. Patil, Jun Xue, Sriram Neelamegham, Jie Xia, E. V. Chandrasekaran, Robert D. Locke
Publikováno v:
Journal of Proteome Research. 11:2609-2618
Our previous studies suggest that the α2,3sialylated T-antigen (NeuAcα2,3Galβ1,3GalNac-) and associated glycan structures are likely to be elevated during cancer. An easy and reliable strategy to label mucinous glycans that contain such carbohydra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5517a1801b7ab7118be73a58f5e4b6
https://doi.org/10.1021/pr201108q
https://doi.org/10.1021/pr201108q
Autor:
Sirajud D. Khaja, E. V. Chandrasekaran, Robert D. Locke, Jun Xue, Khushi L. Matta, Vipin Kumar
Publikováno v:
Tetrahedron. 65:8325-8335
Syntheses of fluorinated mucin core 6 disaccharides and core 2 trisaccharides modified at the C-3 or C-4 position of the pertinent glucosamine residue required for mechanistic study of glycosyltransferases and sulfotransferases involved in the biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba39ca4b9ca6d787df74a578c2c0a2f6
https://doi.org/10.1016/j.tet.2009.07.089
https://doi.org/10.1016/j.tet.2009.07.089
Autor:
Dhananjay Marathe, Joseph T.Y. Lau, E. V. Chandrasekaran, Sriram Neelamegham, Khushi L. Matta
Publikováno v:
The FASEB Journal. 22:4154-4167
The application of systems biology methods in the emerging field of glycomics requires the collection and integration of glycosyltransferase data at the gene and enzyme level for the purpose of hypothesis generation. We systematically examined the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a266407615cc2c8a210713495366e5
https://doi.org/10.1096/fj.07-104257
https://doi.org/10.1096/fj.07-104257
Publikováno v:
Biochemistry. 47:320-330
Sialyltransferases transfer sialic acid from cytidine 5'-monophospho-N-acetylneuraminic acid (CMP-NeuAc) to an acceptor molecule. Trans-sialidases of parasites transfer alpha2,3-linked sialic acid from one molecule to another without the involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65cdec1b65f67692f56b8d5ff0882176
https://doi.org/10.1021/bi701472g
https://doi.org/10.1021/bi701472g
Autor:
E. V. Chandrasekaran, Robert D. Locke, Khushi L. Matta, Thamarapu Srikrishnan, Jie Xia, Jun Xue
Publikováno v:
The Journal of Organic Chemistry. 71:3696-3706
Syntheses of fluorinated mucin core 2 tri- and tetrasaccharides modified at the C-3 or C-4 position of the pertinent galactose residue are reported. These compounds were used for the study of sialyltransferases and 3-O-sulfotransferases involved in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffefca4d3f310b13a08412124f188631
https://doi.org/10.1021/jo052626j
https://doi.org/10.1021/jo052626j
Autor:
Robert D Locke, Jie Xia, Conrad Piskorz, Ram P. Chawda, Sriram Neelamegham, E. V. Chandrasekaran, Jun Xue, Khushi L. Matta
Publikováno v:
Biochemistry. 44:15619-15635
Sialic acids are key determinants in many carbohydrates involved in biological recognition. We studied the acceptor specificities of three cloned sialyltransferases (STs) [alpha2,3(N)ST, alpha2,3(O)ST, and alpha2,6(N)ST] and another alpha2,3(O)ST pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ceb3fcb6b931c977b513e0a9e8d034
https://doi.org/10.1021/bi050246m
https://doi.org/10.1021/bi050246m
Autor:
E V Chandrasekaran, C. R. Kiefer, Joseph Mendicino, Elliott F. Osserman, Takashi Isobe, Fred A. Garver, L. S. Chang
Publikováno v:
European Journal of Biochemistry. 115:648-652
The carbohydrate structure and complete amino acid sequence of a human lambda-type immunoglobulin light chain, protein Sm lambda has been determined. The protein was isolated from the urine of a patient with a plasma cell dyscrasia resembling gamma-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a85e2f0acbc0760e47cd44fc98958a
https://doi.org/10.1111/j.1432-1033.1981.tb06251.x
https://doi.org/10.1111/j.1432-1033.1981.tb06251.x