Zobrazeno 1 - 10
of 25
pro vyhledávání: '"E Tukker"'
Autor:
Marilize E. Tukker
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 69, Iss 1, Pp e1-e8 (2013)
Christians and the church tend to shy away from talking about sex, premarital sex and sex outside of marriage. God and sex are rarely mentioned in the same sentence, and yet people still have a deep need for spirituality, to experience God in their l
Externí odkaz:
https://doaj.org/article/96e94724a37e4b10b6ee83fddc718426
Autor:
M. Danhof, J von Frijtag, Josy M. Gubbens-Stibbe, E Tukker, D Künzel, Eugene H. Cox, P H van der Graaf, M Garrido, Adriaan P. IJzerman
Publikováno v:
Pharmaceutical Research. 17:653-659
Purpose. The objective of this investigation was to determine theinfluence of pre-treatment with the irreversible μ-opioid receptorantagonist β-funaltrexamine (β-FNA) on thepharmacokinetic-pharmacodynamic (PK/PD) relationship of alfentanil in rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c80d351949ae3b4e86b29f388c8832e
https://doi.org/10.1023/a:1007513812018
https://doi.org/10.1023/a:1007513812018
Publikováno v:
British Journal of Pharmacology. 124:607-618
A1 adenosine receptor agonists with reduced intrinsic activity may be therapeutically useful as result of an increased selectivity of action. In this study the tissue selectivity of three 8-alkylamino substituted analogues of N6-cyclopentyladenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0fa5bb6d902423bd3b8486172d4ff9
https://doi.org/10.1038/sj.bjp.0701868
https://doi.org/10.1038/sj.bjp.0701868
Autor:
Eugene H. Cox, Meindert Danhof, E Tukker, Victorine S. Koster, Catherijne A. J. Knibbe, Han J. M. Langemeijer, M. W. E. Langemeijer, Loraine Lie-A-Huen, Rogier Lange, Paul F. M. Kuks
Publikováno v:
Pharmaceutical Research. 15:442-448
Purpose. The influence of different intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol was investigated using the effect on the EEG (11.5-30 Hz) as pharmacodynamic endpoint.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd649474a88323d98d7893b243ba4951
https://doi.org/10.1023/a:1011980432646
https://doi.org/10.1023/a:1011980432646
Publikováno v:
British Journal of Pharmacology. 102:663-668
1. The purpose of the present investigation was to quantify the concentration-pharmacological effect relationship of midazolam in individual rats by use of effect parameters derived from aperiodic EEG analysis. By varying the rate and route of admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bb97269557407beef8b532e24c07d3
https://doi.org/10.1111/j.1476-5381.1991.tb12230.x
https://doi.org/10.1111/j.1476-5381.1991.tb12230.x
Autor:
F. L. C. Wolters, Lambertus A. Peletier, P H van der Graaf, E Tukker, Josy M. Gubbens-Stibbe, M. Danhof, S. A. G. Visser
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 304(1)
A mechanism-based pharmacokinetic-pharmacodynamic (PK/PD) model for neuroactive steroids, comprising a separate characterization of 1) the receptor activation process and 2) the stimulus-response relationship, was applied to various nonsteroidal GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bf6cd46b258341ff62ac4196e7d591
https://pubmed.ncbi.nlm.nih.gov/12490579
https://pubmed.ncbi.nlm.nih.gov/12490579
Publikováno v:
British journal of pharmacology. 124(3)
1. A1 adenosine receptor agonists with reduced intrinsic activity may be therapeutically useful as result of an increased selectivity of action. In this study the tissue selectivity of three 8-alkylamino substituted analogues of N6-cyclopentyladenosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f587e9b07da3c3ab228cecd7efa1060
https://pubmed.ncbi.nlm.nih.gov/9647488
https://pubmed.ncbi.nlm.nih.gov/9647488
Autor:
E H, Cox, C A, Knibbe, V S, Koster, M W, Langemeijer, E E, Tukker, R, Lange, P F, Kuks, H J, Langemeijer, L, Lie-A-Huen, M, Danhof
Publikováno v:
Pharmaceutical research. 15(3)
The influence of different intravenous formulations on the pharmacokinetics and pharmacodynamics of propofol was investigated using the effect on the EEG (11.5-30 Hz) as pharmacodynamic endpoint.Propofol was administered as an intravenous bolus infus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bab18e36cb5a81773fc3ef39d35301b
https://pubmed.ncbi.nlm.nih.gov/9563075
https://pubmed.ncbi.nlm.nih.gov/9563075
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(1)
The plasma to effect site equilibration kinetics and the steady-state plasma concentration-EEG effect relationship of baclofen were characterized after separate administration of racemic baclofen and its two enantiomers. Male Wistar-derived rats rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6163a36b86f8cd5cf6843c847bdd9b6a
https://pubmed.ncbi.nlm.nih.gov/1560387
https://pubmed.ncbi.nlm.nih.gov/1560387
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(1)
The pharmacokinetic and pharmacodynamic interaction between the benzodiazepine agonist midazolam and antagonist flumazenil was quantified in vivo in rats, using effect parameters derived from aperiodic EEG analysis. The benzodiazepine-induced increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78cf382f6d90272203174c56b24e4f4f
https://pubmed.ncbi.nlm.nih.gov/1309878
https://pubmed.ncbi.nlm.nih.gov/1309878