Zobrazeno 1 - 10
of 31
pro vyhledávání: '"E Tinkler-Hundal"'
Autor:
Nicholas P. West, Chloe J Kirkby, Henry M. Wood, E Tinkler-Hundal, Stephen D. Evans, Julia Gala de Pablo
Publikováno v:
The Analyst. 146:581-589
Rectal cancer patients frequently receive pre-operative radiotherapy (RT), prior to surgical resection. However, colorectal cancer is heterogeneous and the degree of tumour response to pre-operative RT is highly variable. There are currently no clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b335d7ad04c747162f18a8bc036954
https://doi.org/10.1039/d0an01803a
https://doi.org/10.1039/d0an01803a
Autor:
Jennifer Kingston, Anna Wilkins, Anguraj Sadanandam, Hannah Bye, David Mansfield, Jessica A. Downs, Elisa Fontana, A Noshirwani, Fiona Errington-Mais, Yatish Patil, Magnus T. Dillon, Katharina von Loga, Paul Carter, Kevin J. Harrington, Gift Nyamundanda, Daniel Bottomley, David Sebag-Montefiore, Sandra Demaria, Nicholas P. West, Chanthirika Ragulan, E Tinkler-Hundal, Alan Melcher
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
BackgroundRectal cancers show a highly varied response to neoadjuvant radiotherapy/chemoradiation (RT/CRT) and the impact of the tumor immune microenvironment on this response is poorly understood. Current clinical tumor regression grading systems at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052136d6546eada06fa12d3ecaa8e106
https://eprints.whiterose.ac.uk/170165/30/e001717.full.pdf
https://eprints.whiterose.ac.uk/170165/30/e001717.full.pdf
Autor:
Gemma E Sheehan-Dare, Claus Anders Bertelsen, Peter Ingeholm, Kate Marks, Phil Quirke, Nicholas P. West, E Tinkler-Hundal
Publikováno v:
Colorectal Disease. 20:105-115
Mesocolic plane surgery with central vascular ligation produces an oncologically superior specimen following colon cancer resection and appears to be related to optimal outcomes. Aim We aimed to assess whether a regional educational programme in opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a63d4346941bcad027319e1777a559
https://doi.org/10.1111/codi.13830
https://doi.org/10.1111/codi.13830
Autor:
E Tinkler-Hundal, Fiona Brew, Philip Quirke, Karen G. Spink, Fiona S. Togneri, Paula Wojtowicz, M Taylor, Assa Oumie, Henry M. Wood, Joseph M. Foster
Publikováno v:
BMC Medical Genomics
Background The importance of accurate and affordable mutation calling in fixed pathology samples is becoming increasingly important as we move into the era of personalised medicine. The Affymetrix OncoScan® Array platform is designed to produce acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71180b169e6b356e1df906b536ac89ea
https://doi.org/10.1186/s12920-017-0254-5
https://doi.org/10.1186/s12920-017-0254-5
Autor:
Fabiana Ramos Vasques, Phil Quirke, Fiona S. Togneri, Katherine E. Keating, Iris Halfpenny, Karen G. Spink, M Taylor, Debra Hau, Dominic J. McMullan, Fiona Brew, Paul Wallace Medlow, E Tinkler-Hundal, K Southward, Joseph M. Foster, Michael J. Griffiths, Keith McGreeghan-Crosby, Assa Oumie
Publikováno v:
BMC Medical Genomics
Background Adoption of new technology in both basic research and clinical settings requires rigorous validation of analytical performance. The OncoScan® FFPE Assay is a multiplexing tool that offers genome-wide copy number and loss of heterozygosity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc93aca624e6f024eb27c9997d7937d8
https://doi.org/10.1186/s12920-015-0079-z
https://doi.org/10.1186/s12920-015-0079-z
Autor:
M Taylor, Phil Quirke, Matthew T. Seymour, Jennifer H. Barrett, Jenny F. Seligmann, Susan D. Richman, Henry M. Wood, E Tinkler-Hundal, Faye Elliott
Publikováno v:
Annals of Oncology. 28:v185
Background: Whilst RAS mutations predict which aCRC patients (pts) will not benefit from anti-EGFR agents, RAS-wt status does not reliably predict who will. Several studies report that high EGFR ligand expression (EREG/AREG) is predictive of anti-EGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdd3e9d21691be873a0e058f07da460a
https://doi.org/10.1093/annonc/mdx393.071
https://doi.org/10.1093/annonc/mdx393.071
Autor:
E Tinkler-Hundal, Neil Corrigan, Matthew A. Goldsworthy, Nicholas P. West, Gemma Gossedge, GW Taylor, Helen Andrew, David Jayne, T Maisey
Publikováno v:
European Journal of Cancer. 72:S61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::824dfb61ec4433b22b388fff0850daf0
https://doi.org/10.1016/s0959-8049(17)30279-4
https://doi.org/10.1016/s0959-8049(17)30279-4
Publikováno v:
Histopathology. 66(4)
Aims Colorectal adenomas measuring 10 mm or more are at increased neoplastic risk and therefore undergo more rigorous follow-up. Currently there is no standardized method of assessing polyp size. We aimed to examine the correlation between endoscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a981dd5c264e58aaa492ac1c885f36c
https://pubmed.ncbi.nlm.nih.gov/24898056
https://pubmed.ncbi.nlm.nih.gov/24898056
Autor:
Matthew A. Goldsworthy, Helen Andrew, David G. Jayne, Gemma Gossedge, GW Taylor, E Tinkler-Hundal, Nicholas P. West, T Maisey
Publikováno v:
European Journal of Surgical Oncology (EJSO). 42:S240
Background: 5-Aminolevulinic acid (5-ALA) selectively accumulates in cancer cells and is metabolised in the mitochondria to the fluorophore protoporphyrin IX. The GLiSten trial evaluated 5-ALA as a fluorescent probe for intraoperative detection of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698b5962b707c8469709da8a0e29000c
https://doi.org/10.1016/j.ejso.2016.07.091
https://doi.org/10.1016/j.ejso.2016.07.091
Autor:
Dominic J. McMullan, Eric T. Fung, M Taylor, Phil Quirke, Karen G. Spink, Michael J. Griffiths, Sofia Alyas, Katherine E. Keating, Fiona S. Togneri, E Tinkler-Hundal, Paula Wojtowicz, Jeanette Schmidt, Joseph M. Foster, K Southward, Henry M. Wood, Assa Oumie, Fiona Brew
Publikováno v:
Cancer Research. 75:626-626
Objectives Copy number (CN) and somatic mutation (SM) analysis in tumors is rapidly gaining importance in cancer management as a tool for differential diagnosis, determination of prognosis, and selection of therapeutic. Genome-wide copy number and LO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d3ff855a974cf9a7eb65a620c097bd
https://doi.org/10.1158/1538-7445.am2015-626
https://doi.org/10.1158/1538-7445.am2015-626