Výsledky vyhledávání - "E T Bonaccio"

Analysis of multiple restriction fragment length polymorphisms of the gene for the human complement receptor type I. Duplication of genomic sequences occurs in association with a high molecular mass receptor allotype

Autor: Christine A. Kennedy, J H Weis, Lloyd B. Klickstein, Winnie W. Wong, E T Bonaccio, James G. Wilson, Douglas T. Fearon

Publikováno v: The Journal of Experimental Medicine

Human CR1 exhibits an unusual form of polymorphism in which allotypic variants differ in the molecular weight of their respective polypeptide chains. To address mechanisms involved in the generation of the CR1 allotypes, DNA from individuals having t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9909e794f7931ee699521679f14721
https://doi.org/10.1084/jem.164.5.1531

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Structure of the human CR1 gene. Molecular basis of the structural and quantitative polymorphisms and identification of a new CR1-like allele

Autor: James G. Wilson, Winnie W. Wong, Lloyd B. Klickstein, E T Bonaccio, Douglas T. Fearon, Christine A. Kennedy, Margaret J. Morris, J M Cahill, M D Rosen

Publikováno v: The Journal of Experimental Medicine

Structural and quantitative polymorphisms have been described in human CR1. In the former, the S allotype is larger than the F allotype by 40-50 kD, the size of a long homologous repeat (LHR). In the latter, homozygotes for a 7.4-kb Hind III fragment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400c40194c1fc0be3b89c7ab70deb5e7
http://europepmc.org/articles/PMC2189269

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