Zobrazeno 1 - 10
of 29
pro vyhledávání: '"E T, Papoutsakis"'
Publikováno v:
Methods in molecular medicine. 18
The culture of hematopoietic cells for cell and gene therapies is a rapidly growing area within the field of applied hematology and tissue engineering. As evidenced by recent clinical trials (1), ex vivo expanded hematopoietic cells offer great promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bf0cc050e34ff39aec31dec29dfb983
https://pubmed.ncbi.nlm.nih.gov/21370184
https://pubmed.ncbi.nlm.nih.gov/21370184
Publikováno v:
Blood. 80:403-411
Expansion of hematopoietic progenitor cells in the mononuclear cell (MNC) fraction of human cord blood was evaluated under atmospheres containing reduced (5%) and normal (20%) oxygen tensions. Cells were cultured with synergistic cytokine combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b979a585b8f472a87fee7b5a0a839b
https://doi.org/10.1182/blood.v80.2.403.bloodjournal802403
https://doi.org/10.1182/blood.v80.2.403.bloodjournal802403
Autor:
J. Lehmann, E. T. Papoutsakis
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0195835a5c3d6def8e64af9e9736100
https://doi.org/10.1007/0-306-46860-3_114
https://doi.org/10.1007/0-306-46860-3_114
Autor:
C. L. Mcdowell, E. T. Papoutsakis
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
The effects of serum medium concentration and culture pH on CD 13 receptor content and mRNA levels of HL60 (human promyelocytic leukemia) cells were examined using flow cytometry and Northern blotting. Increasing the serum concentration from 5% to 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::516594bde07e61854e29b7af3126c31a
https://doi.org/10.1007/0-306-46860-3_53
https://doi.org/10.1007/0-306-46860-3_53
Publikováno v:
British journal of haematology. 111(3)
Megakaryocytes (Mks) mature adjacent to bone marrow (BM) sinus walls and subsequently release platelets within the sinusoidal space or in lung capillaries. As the sites for platelet release have higher levels of oxygen tension (pO(2)) than the core o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fe8ec6009c9cbdb7aa31152f055e5ad
https://pubmed.ncbi.nlm.nih.gov/11122151
https://pubmed.ncbi.nlm.nih.gov/11122151
Publikováno v:
Biotechnology and bioengineering. 72(2)
Ex vivo production of hematopoietic progenitor cells has potential applications for cell therapy to alleviate cytopenias associated with chemotherapy and for gene therapy. In both therapies, progenitor and stem cells are considered crucial factors fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20db1dd59f45b57e0edab3aa7cd5291c
https://pubmed.ncbi.nlm.nih.gov/11114652
https://pubmed.ncbi.nlm.nih.gov/11114652
Autor:
K S, Carswell, E T, Papoutsakis
Publikováno v:
Biotechnology and bioengineering. 68(3)
Ex vivo expansion of T cells is a key step of many cellular immunotherapy protocols, which require large numbers of immune cells to eradicate malignant or virally infected cells. The use of stirred culture systems for T cell expansion offers many pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae0d0604c6cd7c447e4f75456ad56df3
https://pubmed.ncbi.nlm.nih.gov/10745201
https://pubmed.ncbi.nlm.nih.gov/10745201
Autor:
E T, Papoutsakis
Publikováno v:
Biotechnology and bioengineering. 67(6)
A stoichiometric equation has been derived which describes the interrelations among the various products and biomass in fermentations of butyric acid bacteria. The derivation of the equation is based on an assumed ATP yield, two biological regulariti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bbf95bf329bbfaf15de3324e9b33838
https://pubmed.ncbi.nlm.nih.gov/10699860
https://pubmed.ncbi.nlm.nih.gov/10699860
Publikováno v:
Biotechnology and bioengineering. 67(1)
Two metabolic engineering tools, namely gene inactivation and gene overexpression, were employed to examine the effects of two genetic modifications on the fermentation characteristics of Clostridium acetobutylicum. Inactivation of the butyrate kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::645f4d2d30392e5b49c0950d2714eb21
https://pubmed.ncbi.nlm.nih.gov/10581430
https://pubmed.ncbi.nlm.nih.gov/10581430
Autor:
C L, McDowell, E T, Papoutsakis
Publikováno v:
Biotechnology and bioengineering. 60(2)
Flow cytometry and Northern blotting were used to examine the effects of hydrodynamic forces in stirred tank bioreactors on CD13 receptor surface content and mRNA levels of HL60 (human promyelocytic leukemia) cells. A step increase in agitation rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8e59769c2f33d02f694d3023feff054
https://pubmed.ncbi.nlm.nih.gov/10099425
https://pubmed.ncbi.nlm.nih.gov/10099425