Zobrazeno 1 - 10
of 234
pro vyhledávání: '"E Sylvester Vizi"'
Autor:
Cecilia Csölle, Mária Baranyi, Gabriella Zsilla, Agnes Kittel, Flóra Gölöncsér, Peter Illes, Edit Papp, E Sylvester Vizi, Beáta Sperlágh
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66547 (2013)
Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored. In the presen
Externí odkaz:
https://doaj.org/article/27382327741b467e8afd60bc1910c122
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 6, p e1000818 (2010)
Sodium channels are one of the most intensively studied drug targets. Sodium channel inhibitors (e.g., local anesthetics, anticonvulsants, antiarrhythmics and analgesics) exert their effect by stabilizing an inactivated conformation of the channels.
Externí odkaz:
https://doaj.org/article/6de7b317868e4b38b7a15a42584df7bf
Autor:
Nora Lenkey, Robert Karoly, Peter Lukacs, E Sylvester Vizi, Morten Sunesen, Laszlo Fodor, Arpad Mike
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15568 (2010)
BACKGROUND: There is only one established drug binding site on sodium channels. However, drug binding of sodium channels shows extreme promiscuity: ∼25% of investigated drugs have been found to potently inhibit sodium channels. The structural diver
Externí odkaz:
https://doaj.org/article/c8bef075d65b408a8b782793ac3d6928
Autor:
Lumei Huang, Paula Mut-Arbona, Bernadett Varga, Bibiana Török, János Brunner, Antonia Arszovszki, András Iring, Máté Kisfali, E. Sylvester Vizi, Beáta Sperlágh
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107560- (2023)
Summary: ATP-gated P2X7 receptors (P2X7Rs) play a crucial role in brain disorders. However, how they affect normal and pathological synaptic transmission is still largely unclear. Here, by using whole-cell patch-clamp technique to record AMPA- and NM
Externí odkaz:
https://doaj.org/article/4adaf32ed5184b3d9e8a6087adc458e6
Autor:
Viktor Román, Rita Kedves, Kristóf Kelemen, Zsolt Némethy, Beáta Sperlágh, Balázs Lendvai, E. Sylvester Vizi
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract Neuronal networks cause changes in behaviorally important information processing through the vesicular release of neurotransmitters governed by the rate and timing of action potentials (APs). Herein, we provide evidence that dopamine (DA), n
Externí odkaz:
https://doaj.org/article/e408a6cb2205436dbb66a18baeb6f2a5
Akademický článek
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Autor:
Zsolt, Némethy, Béla, Kiss, Natasha, Lethbridge, Paul, Chazot, Tünde, Hajnik, Attila, Tóth, László, Détári, Éva, Schmidt, András, Czurkó, Diána, Kostyalik, Vilmos, Oláh, István, Hernádi, Ottilia, Balázs, E Sylvester, Vizi, István, Ledneczki, Sándor, Mahó, Viktor, Román, Balázs, Lendvai, György, Lévay
Publikováno v:
European journal of pharmacology. 916
The histamine H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d00db9c21eae4a299c02b5487aa1036b
https://pubmed.ncbi.nlm.nih.gov/34965389
https://pubmed.ncbi.nlm.nih.gov/34965389
Autor:
Stefano Calovi, Paula Mut-Arbona, Pál Tod, András Iring, Annette Nicke, Susana Mato, E. Sylvester Vizi, Jan Tønnesen, Beata Sperlagh
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Background: It has been consistently reported that the deficiency of the adenosine triphosphate (ATP) sensitive purinergic receptor P2X7 (P2X7R) ameliorates symptoms in animal models of brain diseases. Objective: This study aimed to investigate the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f19e9cd445ffc168eee806ad681a8a8
https://pubmed.ncbi.nlm.nih.gov/33262687
https://pubmed.ncbi.nlm.nih.gov/33262687
Autor:
Zsolt Némethy, Béla Kiss, Natasha Lethbridge, Paul Chazot, Tünde Hajnik, Attila Tóth, László Détári, Éva Schmidt, András Czurkó, Diána Kostyalik, Vilmos Oláh, István Hernádi, Ottilia Balázs, E. Sylvester Vizi, István Ledneczki, Sándor Mahó, Viktor Román, Balázs Lendvai, György Lévay
Publikováno v:
European Journal of Pharmacology. 916:174621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1beae2435563c1ece7c1fadf0cc0b9b3
https://doi.org/10.1016/j.ejphar.2021.174621
https://doi.org/10.1016/j.ejphar.2021.174621
Publikováno v:
European Journal of Pharmacology. 837:72-80
The addiction-related behavioural effects of drugs of abuse are mediated by the mesocorticolimbic monoamine systems. We investigated the effects of 3,4-methylenedioxymethamphetamine (MDMA), mephedrone, β-phenylethylamine (β-PEA) methylphenidate (MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfce2eeeccaf833d5c1cd13e62c017c
https://doi.org/10.1016/j.ejphar.2018.08.037
https://doi.org/10.1016/j.ejphar.2018.08.037