Zobrazeno 1 - 10
of 28
pro vyhledávání: '"E Swysen"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 6:49-60
The excretion and metabolism of the novel gastrokinetic and antinauseant drug domperidone were studied after oral administration of the 14C-labelled compound to rats, dogs and man, and after intravenous administration to rats and dogs. Excretion of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15afd713b2578ef824911adddee297b
https://doi.org/10.1007/bf03189515
https://doi.org/10.1007/bf03189515
Autor:
W, Meuldermans, J, Hendrickx, W, Lauwers, E, Swysen, R, Hurkmans, F, Knaeps, R, Woestenborghs, J, Heykants
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 12(6)
The excretion and biotransformation of ketanserin, a novel serotonin S2-receptor blocking agent used in hypertension and related diseases, were studied after single po (1 or 10 mg/kg) and iv (2.5 mg/kg) administration in rats and dogs, using two diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a36d0e210f8a2cdf15891ed6a2665127
https://pubmed.ncbi.nlm.nih.gov/6150829
https://pubmed.ncbi.nlm.nih.gov/6150829
Autor:
W, Meuldermans, J, Hendrickx, R, Hurkmans, E, Swysen, R, Woestenborghs, W, Lauwers, J, Heykants
Publikováno v:
Arzneimittel-Forschung. 33(8)
The excretion and metabolism of (E)-1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride (flunarizine hydrochloride, R 14 950, Sibelium) were studied after single oral doses in rats and dogs, using tritium-labelled as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eec5edb9c5a9943513a4958f78204c6f
https://pubmed.ncbi.nlm.nih.gov/6685491
https://pubmed.ncbi.nlm.nih.gov/6685491
Autor:
Robert Woestenborghs, Willem Meuldermans, L. Van Leemput, J. Heykants, E Swysen, L. Michielsen
Publikováno v:
Ecotoxicology and environmental safety. 18(3)
The toxicity of imazalil (enilconazole), of its sulfate salt, and of a principal environmental transformation product to the earthworm species Eisenia foetida was determined. The 48-hr contact test and the 14-day artificial soil test as described by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af101416596d29b3f67c67918142ccd
https://pubmed.ncbi.nlm.nih.gov/2612423
https://pubmed.ncbi.nlm.nih.gov/2612423
Introductory Studies on the Environmental Fate of Azaconazole, A New Fungicide for Wood Preservation
The Freundlich adsorption coefficients (K f a ) for azaconazole were determined on 8 different soils. At room temperature, the mean K f a was 6.56. Adsorption increased with soil organic matter content, soil acidity, and decreasing temperature. Azaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b129435af5d9012891ce6e5953b67ab8
https://doi.org/10.1016/s0166-1116(08)70938-5
https://doi.org/10.1016/s0166-1116(08)70938-5
Autor:
W, Meuldermans, A, Van Peer, J, Hendrickx, W, Lauwers, E, Swysen, M, Bockx, R, Woestenborghs, J, Heykants
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(3)
The excretion and biotransformation of cisapride, a novel gastrokinetic drug, were studied after a single po dose of [14C]cisapride in dogs and humans. The excretion of radioactivity amounted to 97% within 4 days after a 1 mg/kg dose in dogs (72% in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4909c82ef29e5ee99f38b6809177e369
https://pubmed.ncbi.nlm.nih.gov/2900732
https://pubmed.ncbi.nlm.nih.gov/2900732
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 8(4)
After p.o. or i.v. administration of 3H-lorcainide, excretion of the radioactivity was almost complete within four days. In rats and dogs, about 35% of the dose was excreted in the urine and about 60% in the faeces. However, in humans, 62% was excret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b16246fd1f46135bd0fac4b5079ddf5
https://pubmed.ncbi.nlm.nih.gov/6673971
https://pubmed.ncbi.nlm.nih.gov/6673971
Autor:
W, Meuldermans, J, Hendrickx, W, Lauwers, R, Hurkmans, E, Mostmans, E, Swysen, J, Bracke, A, Knaeps, J, Heykants
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(3)
The excretion and biotransformation of cisapride, a novel gastrokinetic drug, were studied after single (10, 40, and 160 mg/kg) and repeated (10 mg/kg/day) po administration to rats, using three different radiolabels. In fasted rats, cisapride was ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30519e7205cb3bbbc04c1dea9c064cc5
https://pubmed.ncbi.nlm.nih.gov/2900733
https://pubmed.ncbi.nlm.nih.gov/2900733
Autor:
W, Meuldermans, J, Hendrickx, W, Lauwers, R, Hurkmans, E, Swysen, J, Thijssen, P, Timmerman, R, Woestenborghs, J, Heykants
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(6)
The excretion and biotransformation of alfentanil (ALF) and sufentanil (SUF), two recent analogues of the synthetic opioid fentanyl, were studied after single iv administration of the tritium-labeled drugs in male rats and dogs. The drugs were almost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55d5a641713baa7b2bbab4e934b4e734
https://pubmed.ncbi.nlm.nih.gov/2893720
https://pubmed.ncbi.nlm.nih.gov/2893720
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