Zobrazeno 1 - 10
of 743
pro vyhledávání: '"E Stillman A"'
Autor:
Insa M. Schmidt, Aditya L. Surapaneni, Runqi Zhao, Dhairya Upadhyay, Wan-Jin Yeo, Pascal Schlosser, Courtney Huynh, Anand Srivastava, Ragnar Palsson, Taesoo Kim, Isaac E. Stillman, Daria Barwinska, Jonathan Barasch, Michael T. Eadon, Tarek M. El-Achkar, Joel Henderson, Dennis G. Moledina, Sylvia E. Rosas, Sophie E. Claudel, Ashish Verma, Yumeng Wen, Maja Lindenmayer, Tobias B. Huber, Samir V. Parikh, John P. Shapiro, Brad H. Rovin, Ian B. Stanaway, Neha A. Sathe, Pavan K. Bhatraju, Josef Coresh, the Kidney Precision Medicine Project, Eugene P. Rhee, Morgan E. Grams, Sushrut S. Waikar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ’s metabolic energy expenditure. Acute tubular injury (ATI) is observed across various types of kidney diseases and may significan
Externí odkaz:
https://doaj.org/article/41855c04b12d4c92a5497040b3021033
Autor:
Carolina Lopez-Silva, Aditya Surapaneni, Insa M. Schmidt, Dhairya Upadhyay, Anand Srivastava, Ragnar Palsson, Isaac E. Stillman, Eugene P. Rhee, Sushrut S. Waikar, Morgan E. Grams
Publikováno v:
Kidney Medicine, Vol 6, Iss 12, Pp 100920- (2024)
Rationale & Objective: Diabetic kidney disease (DKD) is one of the leading causes of end-stage kidney disease globally. We aim to identify proteomic and metabolomic correlates of histologically confirmed DKD that may improve our understanding of its
Externí odkaz:
https://doaj.org/article/edc82158c78f4bb296a073fbf61957d9
Autor:
Sebastian E. Lauro, Elena Pettinelli, Graziella Caprarelli, Jamaledin Baniamerian, Elisabetta Mattei, Barbara Cosciotti, David E. Stillman, Katherine M. Primm, Francesco Soldovieri, Roberto Orosei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
MARSIS attenuation and thermal data confirm that liquid brines are the most plausible source for the bright reflections at the base of the South Polar Layered Deposits. Such results also justify why SHARAD does not penetrate to the base of the ice.
Externí odkaz:
https://doaj.org/article/b8a9a67e32504fb0a072611d38d0cce3
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Flow is a desired but elusive state characterized by the subjective experience of immersion and engagement in an activity. Here, the authors develop and empirically validate a formal model that specifies variables and computations involved in the sub
Externí odkaz:
https://doaj.org/article/e4b21c30b6ca4b9ead4e99bffb599cdf
Autor:
Hao Li, Iannis E. Adamopoulos, Vaishali R. Moulton, Isaac E. Stillman, Zach Herbert, James J. Moon, Amir Sharabi, Suzanne Krishfield, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Splenic marginal zone macrophages can establish immune tolerance and limit the development of systemic lupus erythematosus (SLE). Here the authors show that these cells do this by clearing apoptotic cells, and defects in these cells result in the gen
Externí odkaz:
https://doaj.org/article/e6b55468c2854d60ac861be67cb25f57
Autor:
Ragnar Palsson, Samuel A.P. Short, Zoe A. Kibbelaar, Afolarin Amodu, Isaac E. Stillman, Helmut G. Rennke, Gearoid M. McMahon, Sushrut S. Waikar
Publikováno v:
Kidney International Reports, Vol 5, Iss 4, Pp 511-518 (2020)
Background: The major risk of kidney biopsy is severe bleeding. Numerous risk factors for bleeding after biopsy have been reported, but findings have been inconsistent. Methods: We retrospectively reviewed medical records of adult patients enrolled i
Externí odkaz:
https://doaj.org/article/30bb5a40903e4fcf9f9d6bca82f0956e
Publikováno v:
The Planetary Science Journal, Vol 4, Iss 12, p 232 (2023)
Martian slope streaks are large surface features with lower albedo than their surroundings that are one of the few active geologic processes occurring on Mars today. We investigated the slope streaks’ spectral properties using images from the Compa
Externí odkaz:
https://doaj.org/article/31afc6970ccf4b7bbd36b919c34c2859
Autor:
Gizelle M. McCarthy, Angelo Blasio, Olivia G. Donovan, Lena B. Schaller, Althea Bock-Hughes, Jose M. Magraner, Jung Hee Suh, Calum F. Tattersfield, Isaac E. Stillman, Shrijal S. Shah, Zsuzsanna K. Zsengeller, Balajikarthick Subramanian, David J. Friedman, Martin R. Pollak
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
People of recent sub-Saharan African ancestry develop kidney failure much more frequently than other groups. A large fraction of this disparity is due to two coding sequence variants in the APOL1 gene. Inheriting two copies of these APOL1 risk varian
Externí odkaz:
https://doaj.org/article/a287463f226b4e8fbb37835daa607c31
Autor:
Ali Poyan Mehr, Maryam Sadeghi-Najafabadi, Kristi Chau, Joseph Messmer, Rima Pai, Neil Roy, David Friedman, Martin R. Pollak, Johannes Schlondorff, Mihran Naljayan, Tripti Singh, Stewart H. Lecker, Roger Rodby, Michael Germain, Helmut Rennke, Isaac E. Stillman
Publikováno v:
Kidney International Reports, Vol 4, Iss 1, Pp 20-29 (2019)
Glomerular kidney disorders account for a significant proportion of chronic kidney disease and end-stage renal disease worldwide. Nevertheless, major obstacles make breakthrough progress in diagnosis and cure an ongoing challenge. Here we report the
Externí odkaz:
https://doaj.org/article/e12b0fcdabab47a6b630f384c2e71b50
Autor:
Rhea Bhargava, Sylvain Lehoux, Kayaho Maeda, Maria G. Tsokos, Suzanne Krishfield, Lena Ellezian, Martin Pollak, Isaac E. Stillman, Richard D. Cummings, George C. Tsokos
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Lupus nephritis (LN) is a serious complication occurring in 50% of patients with systemic lupus erythematosus (SLE) for which there is a lack of biomarkers, a lack of specific medications, and a lack of a clear understanding of its pathogenesis. The
Externí odkaz:
https://doaj.org/article/9d9f44188c2d4830bb1e524b3bc42211