Enhancing therapeutic efficacy: In vivo mechanisms and biochemical effects of lycopene encapsulated in nanomicelles for acute inflammation and lipid metabolism.

Autor: Neves-Silva S; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Rio de Janeiro, 21941906, RJ, Brazil., Xavier-de-Britto I; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Rio de Janeiro, 21941906, RJ, Brazil., Gomes-da-Silva NC; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Rio de Janeiro, 21941906, RJ, Brazil., França ÁRS; Biophysics and Nanosystems Laboratory, Federal University of Maranhão, Department of Physics, São Luis, 65065690, MA, Brazil; Center of Sciences of Imperatriz, Federal University of Maranhão, Imperatriz, MA, Brazil., Pedrochi F; Center of Sciences of Imperatriz, Federal University of Maranhão, Imperatriz, MA, Brazil., Queiroz MN; Center of Sciences of Imperatriz, Federal University of Maranhão, Imperatriz, MA, Brazil., Moura-Silva J; Programa de Pós-Graduação em Biociências, Universidade do Estado do Rio de Janeiro, Brazil., Majerowicz D; Programa de Pós-Graduação em Biociências, Universidade do Estado do Rio de Janeiro, Brazil; Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Brazil; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Brazil., Ricci-Junior E; Federal University of Rio de Janeiro, School of Pharmacy, Rio de Janeiro 21941900, RJ, Brazil., Ferreira TPT; Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; Rio de Janeiro Innovation Network in Nanosystems for Health-NanoSAÚDE/FAPERJ, Rio de Janeiro, Brazil., E Silva Martins PMR; Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; Rio de Janeiro Innovation Network in Nanosystems for Health-NanoSAÚDE/FAPERJ, Rio de Janeiro, Brazil., Cai Y; State Key Laboratory of Bioactive Molecules and Druggability Assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Guangdong, China; Key Lab of Traditional Chinese Medicine Informatization/International Science and Technology Cooperation Base of Guangdong Province/School of Pharmacy, Jinan University, Guangzhou, China., Fechine PBA; Advanced Chemistry Materials Group (GQMat) - Analytical Chemistry and Physical Chemistry Department, Federal Unversity of Ceará, - UFC, Campus do Pici, CP 12100, 60451-970 Fortaleza, CE, Brazil., Alencar LMR; Biophysics and Nanosystems Laboratory, Federal University of Maranhão, Department of Physics, São Luis, 65065690, MA, Brazil; Center of Sciences of Imperatriz, Federal University of Maranhão, Imperatriz, MA, Brazil., Sant'anna C; National Institute of Metrology, Quality and Technology, Av. Nossa Sra. das Graças, 50 - Xerém, Duque de Caxias, RJ, 25250-020, Brazil., Santos-Oliveira R; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Rio de Janeiro, 21941906, RJ, Brazil; National Institute of Metrology, Quality and Technology, Av. Nossa Sra. das Graças, 50 - Xerém, Duque de Caxias, RJ, 25250-020, Brazil; Rio de Janeiro State University, Laboratory of Radiopharmacy and Nanoradiopharmaceuticals, Rio de Janeiro, 23070200, RJ, Brazil. Electronic address: roliveira@ien.gov.br.

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Nov 30, pp. 114585. Date of Electronic Publication: 2024 Nov 30.