Zobrazeno 1 - 10
of 72
pro vyhledávání: '"E Scott, Halstead"'
Autor:
Abigail M. Samuelsen, BS, E. Scott Halstead, MD, PhD, Erik B. Lehman, MS, Daniel J. McKeone, MD, Anthony S. Bonavia, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1106 (2024)
OBJECTIVES:. While cytokine response patterns are pivotal in mediating immune responses, they are also often dysregulated in sepsis and critical illness. We hypothesized that these immunological deficits, quantifiable through ex vivo whole blood stim
Externí odkaz:
https://doaj.org/article/4881966473c54550b9446356efd586c9
Autor:
Anthony S. Bonavia, Abigail Samuelsen, Menglu Liang, Jodi Hanson, Daniel McKeone, Zissis C. Chroneos, E. Scott Halstead
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract Background Sepsis is characterized by highly heterogeneous immune responses associated with a spectrum of disease severity. Methods that rapidly and sensitively profile these immune responses can potentially personalize immune-adjuvant thera
Externí odkaz:
https://doaj.org/article/6b7f80b19ab24f1fbce8e70d047f84d9
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2024)
We describe the case of an infant who presented with simple rhinovirus/enterovirus bronchiolitis whose condition worsened with rapid progression to multiple organ dysfunction syndrome (MODS). The patient was presumed to have either primary or seconda
Externí odkaz:
https://doaj.org/article/403e22f08dc541d08bc60acf0f89f4e2
Autor:
Eric Yau, Linlin Yang, Yan Chen, Todd M. Umstead, Hannah Atkins, Zoe E. Katz, Jonathan W. Yewdell, Chintan K. Gandhi, E. Scott Halstead, Zissis C. Chroneos
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Influenza A virus infection (IAV) often leads to acute lung injury that impairs breathing and can lead to death, with disproportionate mortality in children and the elderly. Surfactant Protein A (SP-A) is a calcium-dependent opsonin that binds a vari
Externí odkaz:
https://doaj.org/article/ee1c29f7544b428881aed0e21bc94850
Autor:
John Nguyen, BS, Jill M. Thompson, MS, Daniel R. Balcarcel, MD, Matthew N. Alder, MD, Daniel J. McKeone, MD, E. Scott Halstead, MD, Courtney M. Rowan, MD, Robert B. Lindell, MD, Nadir Yehya, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 1, p e0844 (2023)
IMPORTANCE:. Immunocompromised status, with and without stem cell transplant, confers a worse prognosis in pediatric acute respiratory distress syndrome. An improved understanding of the biochemical profile of immunocompromised children with acute re
Externí odkaz:
https://doaj.org/article/73b10d2031fa4412bf544141a9f0c530
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Highly heterogeneous cell populations require multiple flow cytometric markers for appropriate phenotypic characterization. This exponentially increases the complexity of 2D scatter plot analyses and exacerbates human errors due to variations in manu
Externí odkaz:
https://doaj.org/article/263bece57cb74cbeb38ef89a98bf3153
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
We describe the case of a newborn who presented with multiple organ dysfunction syndrome (MODS) and hyperferritinemia, who eventually met criteria for hemophagocytic lymphohistiocytosis (HLH) due to disseminated herpes simplex virus 1 (HSV-1). While
Externí odkaz:
https://doaj.org/article/d1630da0839d4033a77598a74d42cd6d
Autor:
Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Surfactant Protein-A (SP-A) is a major protein component of surfactant and plays a role in surfactant-related functions and innate immunity. Human SP-A consists of two functional genes, SFTPA1 and SFTPA2, encoding SP-A1 and SP-A2
Externí odkaz:
https://doaj.org/article/a706419cdf7a4e0d9a0d4e3e664fa943
Autor:
E. Scott Halstead, Todd M. Umstead, Michael L. Davies, Yuka Imamura Kawasawa, Patricia Silveyra, Judie Howyrlak, Linlin Yang, Weichao Guo, Sanmei Hu, Eranda Kurundu Hewage, Zissis C. Chroneos
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Influenza A viruses cause life-threatening pneumonia and lung injury in the lower respiratory tract. Application of high GM-CSF levels prior to infection has been shown to reduce morbidity and mortality from pathogenic influenza i
Externí odkaz:
https://doaj.org/article/02b87ee4fa9e4f2b8a3976e638c9ec51
Autor:
Kristin K. Fino, Linlin Yang, Patricia Silveyra, Sanmei Hu, Todd M. Umstead, Susan DiAngelo, E. Scott Halstead, Timothy K. Cooper, Thomas Abraham, Yoshinori Takahashi, Zhixiang Zhou, Hong Gang Wang, Zissis C. Chroneos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract New influenza A viruses that emerge frequently elicit composite inflammatory responses to both infection and structural damage of alveolar-capillary barrier cells that hinders regeneration of respiratory function. The host factors that relin
Externí odkaz:
https://doaj.org/article/9f2db467b2f24fcdb539803d205c307c