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Bromocriptine Improves Central Aortic Stiffness in Adolescents With Type 1 Diabetes: Arterial Health Results From the BCQR-T1D Study

Autor: Michal Schäfer, Lorna P. Browne, Uyen Truong, Petter Bjornstad, Shoshana Tell, Janet Snell-Bergeon, Amy Baumgartner, Kendall S. Hunter, Jane E.B. Reusch, Alex J. Barker, Kristen J. Nadeau, Irene E. Schauer

Publikováno v: Hypertension. 80:482-491

Background: The presence of vascular dysfunction is a well-recognized feature in youth with type 1 diabetes (T1D), accentuating their lifetime risk of cardiovascular events. Therapeutic strategies to mitigate vascular dysfunction are a high clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558f46ea1df8f5f2fcfcfd6960f4982e
https://doi.org/10.1161/hypertensionaha.122.19547

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Sex Differences in Physical Activity Among Individuals With Type 2 Diabetes Across the Life Span: A Systematic Review and Meta-analysis

Autor: Mary O. Whipple, Ana J. Pinto, Layla A. Abushamat, Audrey Bergouignan, Kristina Chapman, Amy G. Huebschmann, Kevin S. Masters, Kristen J. Nadeau, Rebecca L. Scalzo, Irene E. Schauer, Deirdre Rafferty, Jane E.B. Reusch, Judith G. Regensteiner

Publikováno v: Diabetes Care. 45:2163-2177

BACKGROUND Physical activity (PA) is a cornerstone of type 2 diabetes mellitus (T2DM) treatment. Sex differences in PA behavior or barriers/facilitators to PA among individuals with T2DM are unclear. PURPOSE To summarize the evidence related to sex d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90dbfd0e0509ed93773faca841b0d62
https://doi.org/10.2337/dc22-0576

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Akademický článek

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Bromocriptine quick‐release as adjunct therapy in youth and adults with type 1 diabetes: A randomized, placebo‐controlled crossover study

Autor: Shoshana S. Tell, Michal Schafer, Timothy Vigers, Amy D. Baumgartner, Ellen Lyon, Susan Gross, Sarit Polsky, Janet K. Snell‐Bergeon, Irene E. Schauer, Kristen J. Nadeau

Publikováno v: Diabetes, Obesity and Metabolism. 24:2148-2158

To evaluate the potential for glycaemic, renal and vascular benefits of bromocriptine quick release (BCQR) in adolescents and adults with type 1 diabetes.Forty adolescents and 40 adults with type 1 diabetes aged 12-60 years old were enrolled in a dou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1430afbfbce998a2b4eb4ad94c2be2
https://doi.org/10.1111/dom.14800

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Gonadotropin response to insulin and lipid infusion reproduces the reprometabolic syndrome of obesity in eumenorrheic lean women: a randomized crossover trial

Autor: Angela J. Fought, Andrew P. Bradford, Katherine Kuhn, Sara Babcock-Gilbert, Irene E. Schauer, Nanette Santoro

Publikováno v: Fertility and Sterility. 116:566-574

Objective To study the reprometabolic syndrome in normal-weight, eumenorrheic women by infusing a combination of insulin and lipid. Women with obesity have been shown to have reduced gonadotropins and impaired luteinizing hormone (LH) and follicle-st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a8bf6ec4acca4f98c7aa447e9a4c8b
https://doi.org/10.1016/j.fertnstert.2021.03.005

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Single‐leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes

Autor: Nina Kvaratskhelia, Gregory B. Pott, Deirdre Rafferty, Irene E. Schauer, Jane E.B. Reusch, Amy G. Huebschmann, Judith G. Regensteiner, Layla A Abushamat, Melanie Cree-Green, Taro Kaelix Johnson, Rebecca L. Scalzo, Mary O. Whipple, Leslie A. Knaub

Publikováno v: The Journal of Physiology. 600:963-978

KEY POINTS People with type 2 diabetes (T2D) have impaired skeletal muscle oxidative flux due to limited oxygen delivery. In the current study, this impairment in oxidative flux in people with T2D was abrogated with a single-leg exercise training pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec953d3ae0d9418c479cc88dee14c501
https://doi.org/10.1113/jp280603

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414-P: Effects of Obesity and Type 2 Diabetes on Cardiac Structure and Arterial Stiffness

Autor: DANIEL ENGE, MICHAL SCHÄFER, TAKASHI FUJIWARA, ETHAN CLARK, ERIN ENGLUND, REBECCA L. SCALZO, DEIRDRE RAFFERTY, IRENE E. SCHAUER, LAYLA ABUSHAMAT, MARY O. WHIPPLE, KENDALL S. HUNTER, KRISTEN J. NADEAU, JUDITH G. REGENSTEINER, ALEX J. BARKER, JANE REUSCH

Publikováno v: Diabetes. 71

T2D is a global epidemic leading to excess cardiovascular (CV) mortality including heart failure (HF) . Strategies are emerging to prevent HF progression, so early detection is needed. We have identified preclinical cardiac dysfunction associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa5898180b5d0effde4a002c987923e3
https://doi.org/10.2337/db22-414-p

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1331-P: Associations between Insulin Resistance and Plasma Lipids and Metabolomics in Women with and without Type 1 Diabetes

Autor: TIMOTHY B. VIGERS, LAURA PYLE, IRENE E. SCHAUER, BRYAN C. BERGMAN, JANET K. SNELL-BERGEON

Publikováno v: Diabetes. 71

Insulin resistance (IR) increases risk for cardiovascular disease and mortality in people with type 1 diabetes (T1D) . We previously found associations between plasma lipids, metabolites and IR; whether these associations differ in people with and wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67dedb82cea79e3da983237cba5d7055
https://doi.org/10.2337/db22-1331-p

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