Zobrazeno 1 - 10
of 54
pro vyhledávání: '"E S Kleinerman"'
Publikováno v:
The Journal of Immunology. 145:2566-2570
Retroviral infection is associated with immunosuppression, which has been shown to be due, in part, to the action of the envelope protein p15E. We studied a synthetic peptide (CKS-17) homologous to a highly conserved domain of the retroviral envelope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05d7582cdf338c016b515b78c940fa0
https://doi.org/10.4049/jimmunol.145.8.2566
https://doi.org/10.4049/jimmunol.145.8.2566
Autor:
M Sarmiento, E S Kleinerman
Publikováno v:
The Journal of Immunology. 144:1942-1953
Peripheral blood monocytes and lymphocytes isolated from most humans are resistant to HSV infection in vitro. Viral replication is inhibited very early in the cycle, prior to the onset of alpha-protein synthesis; no viral protein or DNA synthesis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f1066e8f59c9bc8fd4d7b43706c7d87
https://doi.org/10.4049/jimmunol.144.5.1942
https://doi.org/10.4049/jimmunol.144.5.1942
Publikováno v:
Cancer research. 61(10)
Expression of Fas (CD95, APO-1), a cell surface receptor capable of inducing ligand-mediated apoptosis, is involved in tissue homeostasis and elimination of targeted cells by natural killer and T cells. Corruption of this pathway, such as reduced Fas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56e9140c8e0eed5ea40333cfc45f0c4e
https://pubmed.ncbi.nlm.nih.gov/11358827
https://pubmed.ncbi.nlm.nih.gov/11358827
Publikováno v:
Cancer research. 61(8)
Overexpression of the HER2/neu oncogene is associated with tumorigenicity and drug resistance in many types of cancer. Three different human Ewing's sarcoma cell lines (TC71, RD, and A4573) were found to express high levels of the HER2/neu protein. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1ad89156264aac7b9b0a33c44ac206e
https://pubmed.ncbi.nlm.nih.gov/11309298
https://pubmed.ncbi.nlm.nih.gov/11309298
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(9)
The purpose of these studies was to determine the effect of adenovirus-mediated interleukin-12 (IL-12) gene transfer on the growth and development of osteosarcoma (OS) lung metastases in nude mice. A nude mouse model was produced by repetitive cyclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e652ee8bbeb496838ea4b07bb1a0fc19
https://pubmed.ncbi.nlm.nih.gov/10999765
https://pubmed.ncbi.nlm.nih.gov/10999765
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(7)
The response rates of relapsed osteosarcoma and melanoma pulmonary metastases to traditional i.v. chemotherapeutic regimens have been disappointing. Direct drug delivery of chemotherapy to the lungs could increase the drug concentration in the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2864776233754a8cffa2231cf5580ef
https://pubmed.ncbi.nlm.nih.gov/10914737
https://pubmed.ncbi.nlm.nih.gov/10914737
Publikováno v:
Clinicalexperimental metastasis. 17(6)
The purpose of these studies was to develop a metastatic osteosarcoma nude mouse model to evaluate the in vivo efficacy of new therapeutic compounds. Human SAOS-2 osteosarcoma cells (10(6) cells) were injected i.v. into nude mice. Cells isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8dfbac421219bbed793a484dfb44cba
https://pubmed.ncbi.nlm.nih.gov/10763916
https://pubmed.ncbi.nlm.nih.gov/10763916
Publikováno v:
Cancer research. 59(18)
Cellular resistance to chemotherapeutic agents is attributable to several mechanisms, including alteration of topoisomerase IIalpha (topo IIalpha) gene expression. Etoposide-resistant MDA-VP human breast cancer cells express lower amounts of enzymati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b87bef052714e9af537ba0e95799cc48
https://pubmed.ncbi.nlm.nih.gov/10493516
https://pubmed.ncbi.nlm.nih.gov/10493516
Autor:
L L, Worth, N, Jaffe, R S, Benjamin, N E, Papadopoulos, S, Patel, A K, Raymond, S F, Jia, C, Rodriguez, J, Gano, M A, Gianan, E S, Kleinerman
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(10)
A Phase II trial using interleukin 1alpha (IL-1alpha) and etoposide for patients with relapsed osteosarcoma (OS) was undertaken to assess the feasibility and tolerability of combination therapy with biotherapy and chemotherapy. Nine patients with his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8803ea44c80246c8c1073d7276a018a9
https://pubmed.ncbi.nlm.nih.gov/9815556
https://pubmed.ncbi.nlm.nih.gov/9815556
Publikováno v:
Oncology research. 8(3)
The etoposide-resistant human breast cancer cell line MDA-VP was derived from MDA-parent cells by sequential selection in increasing concentrations of etoposide. MDA-VP cells express a lower amount of topoisomerase II alpha mRNA than the MDA-parent d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea59617864f1c46a1147a1418a6b04a0
https://pubmed.ncbi.nlm.nih.gov/8823806
https://pubmed.ncbi.nlm.nih.gov/8823806