Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E S Burstein"'
Autor:
E S Burstein, I G Macara
Publikováno v:
Biochemical Journal. 282:387-392
The rab3A gene product is a 25 kDa guanine-nucleotide-binding protein which is expressed at high levels in neural tissue and has about 30% sequence similarity to ras. Purified p25rab3A has been used as substrate to examine its kinetics of nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11682b0caeca778e0423d92ec872d17b
https://doi.org/10.1042/bj2820387
https://doi.org/10.1042/bj2820387
Publikováno v:
Journal of Biological Chemistry. 266:2689-2692
The rab3A gene product is a 25-kilodalton guanine nucleotide-binding protein, expressed at high levels in neural tissue, which has about 30% homology to ras. Recombinant rab3A protein and p25rab3A purified from bovine brain membranes have been used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9af1dad49c741252968db867be3bd7d0
https://doi.org/10.1016/s0021-9258(18)49897-3
https://doi.org/10.1016/s0021-9258(18)49897-3
Autor:
D M, Weiner, E S, Burstein, N, Nash, G E, Croston, E A, Currier, K E, Vanover, S C, Harvey, E, Donohue, H C, Hansen, C M, Andersson, T A, Spalding, D F, Gibson, K, Krebs-Thomson, S B, Powell, M A, Geyer, U, Hacksell, M R, Brann
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
We have used a cell-based functional assay to define the pharmacological profiles of a wide range of central nervous system active compounds as agonists, competitive antagonists, and inverse agonists at almost all known monoaminergic G-protein-couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfc5fd085e74f67318f4a55e0015a7b4
https://pubmed.ncbi.nlm.nih.gov/11561089
https://pubmed.ncbi.nlm.nih.gov/11561089
Autor:
A A, Jensen, T A, Spalding, E S, Burstein, P O, Sheppard, P J, O'Hara, M R, Brann, P, Krogsgaard-Larsen, H, Bräuner-Osborne
Publikováno v:
The Journal of biological chemistry. 275(38)
The calcium-sensing receptor (CaR) belongs to family C of the G-protein-coupled receptor superfamily. To date 14 activating mutations in CaR showing increased sensitivity to Ca(2+) have been identified in humans with autosomal dominant hypocalcemia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::532f9ec5c742817a9644269f907f1876
https://pubmed.ncbi.nlm.nih.gov/10835431
https://pubmed.ncbi.nlm.nih.gov/10835431
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f15edc00b875bc75603320104c0ee2
https://pubmed.ncbi.nlm.nih.gov/9210143
https://pubmed.ncbi.nlm.nih.gov/9210143
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(3)
We have isolated a mutant m5 muscarinic receptor that mediates robust functional responses in the absence of agonists. This constitutively active receptor was isolated from a library of receptors containing randomly introduced mutations in the sixth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99c0256a8eb99b7937288a7892ca5b83
https://pubmed.ncbi.nlm.nih.gov/8531092
https://pubmed.ncbi.nlm.nih.gov/8531092
Publikováno v:
The Journal of biological chemistry. 270(7)
To derive structure-function relationships for receptor-G protein coupling, libraries were created of human m5 muscarinic acetylcholine receptors (m5) randomly mutated in the C-terminal region of the third intracellular loop. Functional receptors wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee3ea708a7371c1479f719ffbc081eaa
https://pubmed.ncbi.nlm.nih.gov/7852396
https://pubmed.ncbi.nlm.nih.gov/7852396
Publikováno v:
The Journal of biological chemistry. 268(30)
The small GTP-binding protein Rab3A (identical to smg p25A) is expressed in neural/exocrine/endocrine cells, is distributed between the cytosol and secretory vesicle membranes, and may cycle between these locations to regulate exocytosis. It is propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::267bf1183d20c0dcf928de10e5fe6fb2
https://pubmed.ncbi.nlm.nih.gov/8226729
https://pubmed.ncbi.nlm.nih.gov/8226729
Publikováno v:
The Journal of biological chemistry. 268(13)
Rab3A is a Ras-like GTPase that is believed to function in regulated secretion. A GTPase activating protein (GAP) and a guanine nucleotide releasing factor (GRF) specific for Rab3A have recently been described. In this study we have described the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faf889de4f9863066e91598b83c98799
https://pubmed.ncbi.nlm.nih.gov/8387493
https://pubmed.ncbi.nlm.nih.gov/8387493
Autor:
I. G. Macara, E. S. Burstein
Publikováno v:
GTPases in Biology I ISBN: 9783642782695
Small Ras-like GTPases function as bipolar molecular switches to control a variety of cellular processes (Bourne et al. 1991a,b). The switches cycle between GTP- and GDP-bound states. Evidence from oncogenic mutants of Ras identified the GTP-bound fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac72759d544ad957d4c94e7678e7064
https://doi.org/10.1007/978-3-642-78267-1_24
https://doi.org/10.1007/978-3-642-78267-1_24
