Zobrazeno 1 - 10
of 42
pro vyhledávání: '"E S Buescher"'
Publikováno v:
Experimental Biology and Medicine. 229:99-107
Pulmonary surfactant with surfactant-associated proteins (PS+SAP) decreases pulmonary inflammation by suppressing neutrophil activation. We have observed that PS+SAP inserts channels into artificial membranes, depolarizes neutrophils, and depresses c
Autor:
P S Hair, E S Buescher
Publikováno v:
Cellular Immunology. 210:87-95
Mastitis is a common complication of human lactation. We examined milk specimens from eight women with clinical mastitis to determine their content of anti-inflammatory components. Antioxidant activity (spontaneous cytochrome c reducing activity), se
Publikováno v:
Pediatrics. 106:1387-1390
Objective. To determine the pathogens associated with fulminant (lethal within 48 hours) late-onset sepsis (occurring after 3 days of age) in a neonatal intensive care unit (NICU) and the frequency of fulminant late-onset sepsis for the most common p
Autor:
P McWilliams-Koeppen, E S Buescher
Publikováno v:
Pediatric Research. 44:37-42
We used column chromatography, affinity binding, and bioassay methods to address whether the soluble tumor necrosis factor (TNF)-alpha receptors present in human colostrum and milk bind to and modify TNF-alpha bioactivity. In gel chromatography exper
Autor:
Walter N. Hittelman, I. Mcalister, Nicholas E. Papadopoulos, Saroj Vadhan-Raj, Michael Andreeff, L. Garrison, Douglas E. Williams, Carl Plager, Juan C. Bandres, Robert S. Benjamin, Shreyaskumar Patel, HE Broxmeyer, Andrew Burgess, E. S. Buescher
Publikováno v:
Blood. 86:2098-2105
PIXY321 is a novel fusion protein of recombinant human granulocyte- macrophage colony-stimulating factor and interleukin-3 that exhibits biologic effects of both its parent cytokines in vitro and in preclinical studies. To evaluate the clinical safet
Autor:
Edward A. Dratz, Daniel W. Siemsen, Mark T. Quinn, John G. Linner, Algirdas J. Jesaitis, E S Buescher
Publikováno v:
Journal of Leukocyte Biology. 57:415-421
Oxidants generated by the NADPH oxidase of activated neutrophils can react with a number of tissue targets to form toxic metabolites such as 4-hydroxynonenal (4-HNE). 4-HNE is a lipid peroxidation product generated by free radical attack on ω-6 poly
Publikováno v:
Infection and Immunity. 58:3002-3008
Locomotion and oxidative metabolism of polymorphonuclear leukocytes from 15 patients receiving recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) were examined in vitro. At the end of each GM-CSF treatment course, polymorphon
Publikováno v:
Journal of Infectious Diseases. 162:109-114
Granulocyte-macrophage colony-stimulating factor (GM-CSF) potentiates in vitro and in vivo production of granulocytes. Also, recombinant human GM-CSF in vitro enhances functional capabilities of human granulocytes. Recombinant murine (rm) GM-CSF was
Publikováno v:
Infection and immunity. 72(5)
Complement-mediated opsonization ofStaphylococcus aureusbearing the dominant capsule serotypes, serotypes 5 and 8, remains incompletely understood. We have previously shown that complement plays a vital role in the efficient phagocytosis of a serotyp