Výsledky vyhledávání - "E S, Severin"

Akademický článek

Antibacterial Activity of the Polymeric Form of Josamycin

Autor: E. D. Nikolskaya, O. A. Zhunina, M. B. Sokol, M. V. Fomicheva, N. V. Gukasova, E. A. Vorontsov, N. G. Yabbarov, O. G. Tereshchenko, E. S. Severin

Publikováno v: Антибиотики и Химиотерапия, Vol 62, Iss 3-4, Pp 18-24 (2020)

The polymeric form ofjosamycin was developed by loading of the antibiotic into spherical submicron particles made of poly(DL- lactide-co-glycolide) (PLGA 50/50) by double emulsion method. The average diameter and zeta-potential of particles synthesiz

Externí odkaz: https://doaj.org/article/03d81204b53b4cd7a4eec21b467c29f9

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Akademický článek

SCIENTIFIC SCHOOL OF ACADEMICIAN VITALY I. SHVETS: BIONANOPHARMACEUTICAL TECHNOLOGIES OF INNOVATIVE DIRECTED-ACTION MEDICINAL PREPARATIONS AND MANPOWER TRAINING

Autor: V. I. Shvets, G. M. Sorokoumova, A. I. Lyutik, A. B. Pshenichnikova, D. I. Prokhorov, N. V. Rukosueva, A. G. Yakovenko, A. M. Khort, S. N. Chvalun, Yu. M. Krasnopolsky, V. Yu. Balabanyan, E. S. Severin, A. A. Kubatiev

Publikováno v: Тонкие химические технологии, Vol 12, Iss 6, Pp 5-31 (2017)

The results of many years of scientific research in the field of physico-chemical biology and its most important direction - lipidology, conducted by the leading scientific school under the leadership of Academician RAS Vitaly I. Shvets, are reported

Externí odkaz: https://doaj.org/article/81965a0b7e354018b3ced4226cf333d9

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Type of pH sensitive linker reveals different time-dependent intracellular localization, in vitro and in vivo efficiency in alpha-fetoprotein receptor targeted doxorubicin conjugate

Autor: M. R. Faustova, O. A. Zhunina, N. G. Yabbarov, M. D. Mollaev, E. S. Severin, Neonila V. Gorokhovets, Irina A. Zamulaeva, A. Zabolotsky, M. Sokol, E. D. Nikolskaya

Publikováno v: International Journal of Pharmaceutics. 559:138-146

Despite the presence of a variety of modern anticancer drugs at the market, doxorubicin (Dox) is still widely used in antineoplastic therapy, although its administration causes severe side effects. To enhance specific activity of such molecules, vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd839b0f1529940a7045ea3f3a52830b
https://doi.org/10.1016/j.ijpharm.2018.12.073

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Formulation of perspective hepatoprotector polymeric forms based on silybin and ursodeoxycholic acid

Autor: M. B. Sokol, E. D. Nikolskaya, V. V. Zavarzina, N. V. Gukasova, N. G. Yabbarov, E. S. Severin, O. G. Tereshchenko, M. V. Fomicheva, O. A. Zhunina, E. V. Zubkov

Publikováno v: Russian Chemical Bulletin. 67:2290-2296

Silybin (Slb) and ursodeoxycholic acid (UDCA) are hepatoprotectors used in the pathogenetic therapy of liver and biliary tract. However, low bioavailability of these drugs restricts their application. In order to solve this problem, Slb and UDCA were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85a44bbc60c413e0927266066cecf717
https://doi.org/10.1007/s11172-018-2372-4

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Development of a polymer system for the delivery of daunorubicin to tumor cells to overcome drug resistance

Autor: M. D. Mollaev, M. B. Sokol, E. D. Nikolskaya, E. S. Severin, M. R. Faustova, A. V. Lobanov, N. V. Gukasova, N. G. Yabbarov, O. A. Zhunina, Vitaliy I. Shvets

Publikováno v: Russian Chemical Bulletin. 67:747-756

Method for the synthesis of polymeric nanoparticles (NP) with encapsulated daunorubicin (DNR) was developed on the basis of double emulsion solvent evaporation technique using biodegradable poly(lactide-co-glycolide) (PLGA), which is aimed at customi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::221d1c54b0f886675e08bdbcb7fa5afe
https://doi.org/10.1007/s11172-018-2132-5

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SCIENTIFIC SCHOOL OF ACADEMICIAN VITALY I. SHVETS: BIONANOPHARMACEUTICAL TECHNOLOGIES OF INNOVATIVE DIRECTED-ACTION MEDICINAL PREPARATIONS AND MANPOWER TRAINING

Autor: A. M. Khort, E. S. Severin, A. I. Lyutik, A. B. Pshenichnikova, V. I. Shvets, A. A. Kubatiev, D. I. Prokhorov, S. N. Chvalun, A. G. Yakovenko, G. M. Sorokoumova, V. Yu. Balabanyan, Yu. M. Krasnopolsky, N. V. Rukosueva

Publikováno v: Тонкие химические технологии, Vol 12, Iss 6, Pp 5-31 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71960e98e38c406bdaeb3757a1e037a
https://www.finechem-mirea.ru/jour/article/view/121

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Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids

Autor: A. V. Lobanov, M. B. Sokol, O. G. Tereshchenko, V. A. Zenin, M. V. Fomicheva, E. S. Severin, N. G. Yabbarov, E. D. Nikolskaya, O. A. Zhunina

Publikováno v: Russian Chemical Bulletin. 66:1867-1872

Polymer particles containing carboplatin (CPt) were developed by the inclusion of this antitumor agent in a copolymer of lactic and glycolic acids (PLGA-COOH 50/50). The polymer particles were found to have a spherical form with an average diameter n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfa92d9c0d5ed4405c7b7230efdb5973
https://doi.org/10.1007/s11172-017-1959-5

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Preparation of temozolomide-loaded polymer particles and study of their antitumor activity in models of glioma and melanoma

Autor: E. D. Nikolskaya, M. B. Sokol, V. I. Popenko, O. A. Zhunina, E. A. Vasilenko, E. S. Severin, O. G. Tereshchenko, N. G. Yabbarov

Publikováno v: Russian Journal of Bioorganic Chemistry. 43:552-560

Temozolomide (TMZ) is a cytostatic drug used in treatment of patients with malignant gliomas and melanomas. The development of innovative formulations for delivery of TMZ into target cells in order to reduce its systemic toxicity and gain prolonged e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f044ced4ec0f7eadf298e2e32dbc9fee
https://doi.org/10.1134/s1068162017050090

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The docetaxel polymeric form and its antitumor activity

Autor: N. G. Yabbarov, E. D. Nikolskaya, N. V. Gukasova, O. G. Tereshchenko, A. V. Godovannyy, E. S. Severin, O. A. Zhunina

Publikováno v: Russian Journal of Bioorganic Chemistry. 43:278-285

A new pharmaceutical form of the antitumor drug docetaxel (Dtx) has been developed based on a biodegradable copolymer of lactic and glycolic acids (PLGA 50/50). This form was constituted of polymeric particles (250 to 300 nm in size) and was highly a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::deef231145048c3b6c6a3f8c00f8a420
https://doi.org/10.1134/s1068162017030116

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Polyamidoamine dendrimers with different surface charge as carriers in anticancer drug delivery

Autor: Irina A. Zamulaeva, I. G. Kondrasheva, N. G. Yabbarov, O. A. Zhunina, E. S. Severin, E. D. Nikolskaya

Publikováno v: Russian Journal of Bioorganic Chemistry. 43:155-162

Second-generation (G2) polyamidoamine (PAMAM) dendrimers are branched polymers containing 16 surface primary amine groups. Due to their structural properties, these polymers can be used as universal carriers in various drug delivery systems. Amine-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e274194b52687c1e9a26cc8da89eb54
https://doi.org/10.1134/s1068162017020182

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