Zobrazeno 1 - 10
of 110
pro vyhledávání: '"E S, Krol'"'
Autor:
Li Shen, Emily Pisha, Richard B. van Breemen, John M. Pezzuto, Suzanne L. Iverson, Zhiwen Huang, Judy L. Bolton, E. S. Krol
Publikováno v:
Chemico-Biological Interactions. 106:133-148
Catechols are widespread in the environment, especially as constituents of edible plants. A number of these catechols may undergo oxidative metabolism to electrophilic o-quinones (3,5-cyclohexadien-1,2-dione) by oxidative enzymes such as cytochrome P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5285740e6311b940c8a72fee81f7e0ee
https://doi.org/10.1016/s0009-2797(97)00066-5
https://doi.org/10.1016/s0009-2797(97)00066-5
Autor:
E. S. Krol, Judy L. Bolton
Publikováno v:
Chemico-Biological Interactions. 104:11-27
Numerous phenols and catechols are known to be substrates for tyrosinase. While the catalytic mechanism of phenol oxidation by tyrosinase has been well studied, little work has been done to determine the influence of substituents on the reaction. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3051821444a37a6ffe4cb5f31e965efb
https://doi.org/10.1016/s0009-2797(97)03763-0
https://doi.org/10.1016/s0009-2797(97)03763-0
Publikováno v:
ChemInform. 25
Hydroxide-dependent hydrolysis of triesters of phosphonoformic acid (PFA)via P–O bond cleavage proceeds at rates 103–106 times greater than hydrolysis of simple phosphonates. The means by which an α-carbonyl substituent elicits such a rate enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf3630d6d08f483e919a54fd17163dc
https://doi.org/10.1002/chin.199432176
https://doi.org/10.1002/chin.199432176
Autor:
John M. Pezzuto, Z Alam, Z Huang, Judy L. Bolton, Emily Pisha, E. S. Krol, L. Shen, RB van Breemen
Publikováno v:
Carcinogenesis. 18(5)
There is a clear association between excessive exposure to estrogens and the development of cancer in several tissues including breast and endometrium. The risk factors for women developing these cancers are all associated with longer estrogen exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815bf4763377fadef554afd3eaca1c68
https://pubmed.ncbi.nlm.nih.gov/9163701
https://pubmed.ncbi.nlm.nih.gov/9163701
Publikováno v:
Chemical research in toxicology. 8(3)
The effects of p-alkyl substituents on the relative cytotoxicity of 4-alkyl-2-methoxyphenols were investigated in isolated rat liver slices. The derivatives of 4-alkyl-2-methoxyphenol studied were 4-methyl- (creosol), 4-ethyl-, 4-propyl-, 4-isopropyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a4fa0e1d912a28e1bf847d741daea8
https://pubmed.ncbi.nlm.nih.gov/7578916
https://pubmed.ncbi.nlm.nih.gov/7578916
Autor:
N Iu, Kuprina, E S, Krol', M Iu, Koriabin, V M, Bannikov, A V, Kirillov, V M, Zakhar'ev, V L, Larionov
Publikováno v:
Molekuliarnaia biologiia. 27(3)
Earlier we have identified the chl4-1 mutation in a screen for yeast mutants with increased loss of chromosome III and circular artificial minichromosome in mitosis. Mutation in the CHL4 gene leads to a 50-100-fold promotion in the rate of chromosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23dd4f6b69c5a3dfac6f677d833d50ac
https://pubmed.ncbi.nlm.nih.gov/8316241
https://pubmed.ncbi.nlm.nih.gov/8316241
Autor:
N Iu, Kuprina, E S, Krol', M Iu, Koriabin, B V, Shestopalov, V V, Bliskovskiĭ, V M, Bannikov, R Z, Gizatullin, A V, Kirillov, V Iu, Kravtsov, V M, Zakhar'ev
Publikováno v:
Molekuliarnaia biologiia. 27(3)
We have analyzed the CHL15 gene, earlier identified in a screen for yeast mutants with increased loss of chromosome III and artificial circular and linear chromosomes in mitosis. Mutations in the CHL15 gene lead to a 100-fold increase in the rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::397902b81cb758db6942c0aaf5c45b74
https://pubmed.ncbi.nlm.nih.gov/8316240
https://pubmed.ncbi.nlm.nih.gov/8316240
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :683
Hydroxide-dependent hydrolysis of triesters of phosphonoformic acid (PFA)via P–O bond cleavage proceeds at rates 103–106 times greater than hydrolysis of simple phosphonates. The means by which an α-carbonyl substituent elicits such a rate enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b120b995d2846f9b43f6f3da61c6034
https://doi.org/10.1039/p29940000683
https://doi.org/10.1039/p29940000683
Autor:
E. S. Krol, Gregory R. J. Thatcher
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :793
The base-catalysed hydrolysis of triesters of phosphonoformic acid via P–O bond cleavage proceeds at rates at least 104 times greater than diethyl difluoromethylphosphonate and 106 times greater than diphenyl methylphosphonate. Buffer catalysis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124aa5194537d1c224125eda96fb1157
https://doi.org/10.1039/p29930000793
https://doi.org/10.1039/p29930000793
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :118
Phosphonoformate triesters are hydrolysed to mixtures of hydrogen phosphonate and phosphonoformate esters and free acids; the rates and product distribution are dependent on pH and ester leaving group abilities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7002bda3c791d5acd11dfec559d1a0f9
https://doi.org/10.1039/c39910000118
https://doi.org/10.1039/c39910000118