Zobrazeno 1 - 10
of 1 257
pro vyhledávání: '"E Robson"'
Autor:
Sara P. Myers, Varadan Sevilimedu, Andrea V. Barrio, Audree B. Tadros, Anita Mamtani, Mark E. Robson, Monica Morrow, Minna K. Lee
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract BRCA1 and BRCA2 pathogenic variant carriers develop breast cancers with distinct pathological characteristics and mutational signatures that may result in differential response to chemotherapy. We compared rates of pathologic complete respon
Externí odkaz:
https://doaj.org/article/56dd88e241294d48ac3caf9f3c9e9350
Autor:
Nicholas C. Turner, A. Douglas Laird, Melinda L. Telli, Hope S. Rugo, Audrey Mailliez, Johannes Ettl, Eva-Maria Grischke, Lida A. Mina, Judith Balmaña, Peter A. Fasching, Sara A. Hurvitz, Julia F. Hopkins, Lee A. Albacker, Jijumon Chelliserry, Ying Chen, Umberto Conte, Andrew M. Wardley, Mark E. Robson
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract These analyses explore the impact of homologous recombination repair gene mutations, including BRCA1/2 mutations and homologous recombination deficiency (HRD), on the efficacy of the poly(ADP-ribose) polymerase (PARP) inhibitor talazoparib i
Externí odkaz:
https://doaj.org/article/38e11546389a453baf13464d8594cd8f
Autor:
Jada G. Hamilton, Ibrahim H. Shah, Caroline Salafia, Elizabeth Schofield, Margaux Genoff Garzon, Kechna Cadet, Zsofia K. Stadler, Jennifer L. Hay, Kenneth Offit, Mark E. Robson
Publikováno v:
PEC Innovation, Vol 2, Iss , Pp 100124- (2023)
Objective: Tumor genomic profiling (TGP) can inform advanced cancer patients’ treatment decisions, and also reveal secondary germline findings—information about inherited risks for cancer and other disorders. We sought to develop a measure of pat
Externí odkaz:
https://doaj.org/article/c0a7827d6e7e4c30a8a5db78f5cba818
Autor:
Emanuela Ferraro, Jasmeet Singh, Sujata Patil, Pedram Razavi, Shanu Modi, Sarat Chandarlapaty, Andrea V. Barrio, Rachna Malani, Ingo K. Mellinghoff, Adrienne Boire, Hannah Y. Wen, Edi Brogi, Andrew D. Seidman, Larry Norton, Mark E. Robson, Chau T. Dang
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract The addition of pertuzumab (P) to trastuzumab (H) and neoadjuvant chemotherapy (NAC) has decreased the risk of distant recurrence in early stage HER2-positive breast cancer. The incidence of brain metastases (BM) in patients who achieved pat
Externí odkaz:
https://doaj.org/article/5efc975ad4074b27a5124e022f559502
Autor:
David Joon Ho, M. Herman Chui, Chad M. Vanderbilt, Jiwon Jung, Mark E. Robson, Chan-Sik Park, Jin Roh, Thomas J. Fuchs
Publikováno v:
Journal of Pathology Informatics, Vol 14, Iss , Pp 100160- (2023)
Deep learning has been widely used to analyze digitized hematoxylin and eosin (H&E)-stained histopathology whole slide images. Automated cancer segmentation using deep learning can be used to diagnose malignancy and to find novel morphological patter
Externí odkaz:
https://doaj.org/article/ac5a85b0b8734246ac67e2c516a8f4e9
Autor:
Suzanne C. O’Neill, Jada G. Hamilton, Claire C. Conley, Beth N. Peshkin, Rosalba Sacca, Glynnis A. McDonnell, Claudine Isaacs, Mark E. Robson, Kenneth P. Tercyak
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Consensus and evidence suggest that cascade testing is critical to achieve the promise of cancer genetic testing. However, barriers to cascade testing include effective family communication of genetic risk information and family members’ a
Externí odkaz:
https://doaj.org/article/178f79f699624308b90015fdbef6d7a2
Autor:
Giulia Petrone, Charles Gaulin, Andriy Derkach, Ashwin Kishtagari, Mark E. Robson, Rekha Parameswaran, Eytan M. Stein
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
We aim to identify predictors of therapy-related myeloid neoplasms (t-MN) in patients with breast cancer (BC) and cytopenias to determine the timing of bone marrow biopsy (BMBx). Patients with BC and cytopenias who were referred for BMBx between 2002
Externí odkaz:
https://doaj.org/article/07691a1fc7e04c9a9636decbe4dbbbdd
Autor:
Xuemei Ji, Semanti Mukherjee, Maria Teresa Landi, Yohan Bosse, Philippe Joubert, Dakai Zhu, Ivan Gorlov, Xiangjun Xiao, Younghun Han, Olga Gorlova, Rayjean J. Hung, Yonathan Brhane, Robert Carreras-Torres, David C. Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C. Aldrich, William S. Bush, Adonina Tardon, Gad Rennert, Chu Chen, Jinyoung Byun, Konstantin H. Dragnev, John K. Field, Lambertus FA. Kiemeney, Philip Lazarus, Shan Zienolddiny, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Pier A. Bertazzi, Angela C. Pesatori, Nancy Diao, Li Su, Lei Song, Ruyang Zhang, Natasha Leighl, Jakob S. Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H. F. M. van der Heijden, Jin Hee Kim, Michael P. A. Davies, Michael W. Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C. Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Gary E. Goodman, Angela Cox, Fiona Taylor, Penella Woll, Erich Wichmann, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M. Arnold, Eric B. Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M. Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Lesley M. Butler, Kenneth Offit, Preethi Srinivasan, Chaitanya Bandlamudi, Matthew D. Hellmann, David B. Solit, Mark E. Robson, Charles M. Rudin, Zsofia K. Stadler, Barry S. Taylor, Michael F. Berger, Richard Houlston, John McLaughlin, Victoria Stevens, David C. Nickle, Ma’en Obeidat, Wim Timens, María Soler Artigas, Sanjay Shete, Hermann Brenner, Stephen Chanock, Paul Brennan, James D. McKay, Christopher I. Amos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
In lung cancer, relatively few germline mutations are known to impact risk. Here the authors looked at rare variants in 39,146 individuals and find novel germline mutations associated with risk, as well as implicating ATM and a new candidate gene for
Externí odkaz:
https://doaj.org/article/98db56edb20d4123b824401859c438ab
Autor:
Jennifer L. Hay, Erica H. Lee, Stephanie N. Christian, Elizabeth Schofield, Jada G. Hamilton, Ciyu Yang, Bobak Hedayati, Keimya Sadeghi, Mark E. Robson, Allan Halpern, Liying Zhang, Irene Orlow
Publikováno v:
Journal of Skin Cancer, Vol 2022 (2022)
Public access to genetic information is increasing, and community dermatologists may progressively encounter patients interested in genetic testing for melanoma risk. Clarifying potential utility will help plan for this inevitability. We determined i
Externí odkaz:
https://doaj.org/article/ae40dd67f0a2412bbfbd0d680e049af8
Autor:
Kelsey E. Breen, Heather Symecko, Kelsey Spielman, Rebecca Gebert, Ibrahim H. Shah, Stacy Pundock, Melissa Batson, Vivek K. Narayan, Zsofia K. Stadler, Karen A. Autio, Wassim Abida, Daniel C. Danila, Howard I. Scher, Michael J. Morris, Jada G. Hamilton, Mark E. Robson, Susan M. Domchek, Maria I. Carlo
Publikováno v:
Journal of Urology. 209:918-927