Zobrazeno 1 - 10
of 29
pro vyhledávání: '"E R Pettipher"'
Publikováno v:
The Journal of Immunology. 159:383-390
The effect of nitric oxide synthase (NOS) inhibitors on plasma extravasation in a rat model of zymosan-induced inflammation has been investigated. Plasma extravasation was determined in response to intradermal test agents over 0 to 45 min or 0 to 4 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98a5d2f2b51d4f422c9803b33d97e9a
https://doi.org/10.4049/jimmunol.159.1.383
https://doi.org/10.4049/jimmunol.159.1.383
Publikováno v:
British Journal of Pharmacology. 117:1530-1534
1. The role of adrenal hormones in the regulation of the systemic and local production of tumour necrosis factor (TNF alpha) was examined in male Balb/c mice. 2. Intraperitoneal injection of 0.3 mg E. coli lipopolysaccharide (LPS, 0111:B4) led to hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95023562be0c8b51593d3d58dfa661e
https://doi.org/10.1111/j.1476-5381.1996.tb15317.x
https://doi.org/10.1111/j.1476-5381.1996.tb15317.x
Autor:
Ronald P. Gladue, Henry J. Showell, D. N. Scampoli, E. D. Salter, E. R. Pettipher, L A Carroll, L Contillo, A J Milici, Hans Stukenbrok
Publikováno v:
The Journal of Experimental Medicine
Leukotriene B4 (LTB4) is a chemotactic and cell-activating factor present at inflammatory sites in a variety of autoimmune diseases including multiple sclerosis (MS). In this study, we used a murine model of MS, experimental allergic encephalomyeliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6606a22daa05a4bc9456afd176f38a3d
http://europepmc.org/articles/PMC2192487
http://europepmc.org/articles/PMC2192487
Autor:
E. R. Pettipher, Allen J. Duplantier, K. L. Johnson, Kenneth G. Kraus, R. J. Chambers, T. A. Hibbs, John B. Cheng, Anthony Marfat, E. D. Salter, John P. Umland, T. H. Jenkinson, J.T. Shirley, V. L. Cohan, David B. Damon
Publikováno v:
ChemInform. 28
Tumor necrosis factor-α (TNF-α) has been implicated as a key mediator in the progression of rheumatoid arthritis. Inhibitors of phosphodiesterase IV (PDE IV) have been shown to inhibit the production of TNF-α by elevating intracellular levels of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b4411bdb87585bc5d357137963c635
https://doi.org/10.1002/chin.199729128
https://doi.org/10.1002/chin.199729128
Publikováno v:
Arthritis & Rheumatism. 33:241-246
Chronic monarticular arthritis can be induced in ovalbumin-sensitized rabbits by intraarticular injection of ovalbumin (antigen-induced arthritis) or in naive rabbits by injecting hyaluronic acid mixed with the polycation poly-D-lysine (polycation-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca6e9c5783df712cd3627323497afe3
https://doi.org/10.1002/art.1780330213
https://doi.org/10.1002/art.1780330213
Autor:
M. S. Biggers, A J Milici, E. R. Pettipher, John B. Cheng, R. Breslow, H.J. Showell, Lawrence S. Melvin, Lawrence A. Reiter, R. J. Griffiths, Kevin Koch
Publikováno v:
Journal of Medicinal Chemistry. 37:3197-3199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55692bdaa5d8784764df54f1797eeae
https://doi.org/10.1021/jm00046a001
https://doi.org/10.1021/jm00046a001
Autor:
H J, Showell, M J, Conklyn, R, Alpert, G P, Hingorani, K F, Wright, M A, Smith, E, Stam, E D, Salter, D N, Scampoli, S, Meltzer, L A, Reiter, K, Koch, A D, Piscopio, S R, Cortina, A, Lopez-Anaya, E R, Pettipher, A J, Milici, R J, Griffiths
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
CP-195543 [(+)-2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid] is a structurally novel, selective and potent leukotriene B4 (LTB4) receptor antagonist. In vitro CP-195543 inhibited [3H]LTB4 binding to high-affinity LTB4 receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8820a50f6b81802f34218a6f301f753
https://pubmed.ncbi.nlm.nih.gov/9618393
https://pubmed.ncbi.nlm.nih.gov/9618393
Autor:
E. D. Salter, E. R. Pettipher, T. A. Hibbs, Frank M. DiCapua, Jon Bordner, Kleinman Edward F, Cohan Victoria L, T. H. Jenkinson, E. Campbell, J.T. Shirley, Giordano La, John B. Cheng
Publikováno v:
Journal of medicinal chemistry. 41(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9628007d8d93254fb4f578b015094593
https://pubmed.ncbi.nlm.nih.gov/9464356
https://pubmed.ncbi.nlm.nih.gov/9464356
Autor:
J B, Cheng, J W, Watson, C J, Pazoles, J D, Eskra, R J, Griffiths, V L, Cohan, C R, Turner, H J, Showell, E R, Pettipher
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
Rolipram was previously reported to elevate plasma cyclic adenosine 3',5'-monophosphate (cAMP) and inhibit serum tumor necrosis factor-alpha (TNF-alpha) production in mice. CP-80,633, a new cyclic nucleotide phosphodiesterase (PDE4) inhibitor, has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74190061f47b2e92bb53526ae046cbec
https://pubmed.ncbi.nlm.nih.gov/9023272
https://pubmed.ncbi.nlm.nih.gov/9023272
Autor:
J. M. Labasi, Arthur Adam Nagel, E. R. Pettipher, L. E. Nichols, E. D. Salter, W. S. Faraci, Lawrence A. Vincent, H. Xu, Kimberly A. Verdries
1. The ability of 2-amino-4-methylpyridine to inhibit the catalytic activity of the inducible NO synthase (NOS II) enzyme was characterized in vitro and in vivo. 2. In vitro, 2-amino-4-methylpyridine inhibited NOS II activity derived from mouse RAW 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0abf613ac29f7810f4c1d9f0f711c6e
https://europepmc.org/articles/PMC1915898/
https://europepmc.org/articles/PMC1915898/
