Zobrazeno 1 - 10
of 35
pro vyhledávání: '"E R Macagno"'
Publikováno v:
Journal of neurobiology. 45(1)
Accumulating evidence indicates that receptor protein tyrosine phosphatases (rPTPs) play major roles in growth cone migration. We have previously shown that the growth cones of the multiple parallel processes of an identified leech embryonic cell, th
Autor:
M W, Baker, E R, Macagno
Publikováno v:
Journal of neurobiology. 44(2)
Among the many cells or parts of cells that a growth cone may encounter during its embryonic migrations are other processes or parts of its parent cell. Such an event can be expected to be relatively frequent in the genesis of neuronal arbors, for in
Autor:
B M, Alberts, F J, Ayala, D, Botstein, E, Frank, E W, Holmes, R D, Lee, E R, Macagno, P, Marrack, S, Oparil, S H, Orkin, A H, Rubenstein, C W, Slayman, P F, Sparling, L R, Squire, P H, von Hippel, K R, Yamamoto
Publikováno v:
Science (New York, N.Y.). 285(5428)
Publikováno v:
Journal of neurobiology. 40(1)
Netrins are secreted, diffusible proteins that direct axonal growth. To study the functions of netrins in the relatively simple and easily accessible nervous system of the leech Hirudo medicinalis, we have cloned a leech netrin and have characterized
Autor:
H, Wang, E R, Macagno
Publikováno v:
Journal of neurobiology. 35(1)
The multiple peripheral projections of a single leech mechanosensory neuron form individual arbors that do not overlap at all with each other, a phenomenon that has been termed "self-avoidance" (Yau, 1976; Kramer and Stent, 1985). This is in marked c
Publikováno v:
Journal of neurobiology. 34(4)
Several days after the completion of the early phase of cell proliferation that generates most of the leech central nervous system, the pair of "sex ganglia" in the two reproductive segments of the midbody undergo a second period of neurogenesis that
Publikováno v:
Journal of neurobiology. 33(1)
To explore possible neurogenic functions of the genes of the Hox/HOM complexes, we injected the mRNA from the leech homeobox genes Lox1 and Lox4 into adult neurons that normally do not express them. The ectopic expression of Lox1 induced a specific t
Publikováno v:
EXS. 72
The Antennapedia-class homeobox genes are likely to play a role in the specification of neuronal identities in invertebrates. The leech Hirudo medicinalis, a species well-suited for the analysis of these genes at the level of identified neurons, cont
Publikováno v:
Annual Review of Biophysics and Bioengineering. 9:347-362
Autor:
W Q, Gao, E R, Macagno
Publikováno v:
Journal of Neurobiology. 18:43-59
The role of homologues in the establishment of the pattern of axonal projections of identified segmentally homologous neurons was investigated by means of selective cell ablation and dye injection. The cells studied were the bilateral pairs of heart