Zobrazeno 1 - 10
of 16
pro vyhledávání: '"E R, Peskind"'
Autor:
L S, Schneider, D A, Bennett, M R, Farlow, E R, Peskind, M A, Raskind, M, Sano, Y, Stern, S, Haneline, K A, Welsh-Bohmer, J, O'Neil, R, Walter, S, Maresca, M, Culp, R, Alexander, A M, Saunders, D K, Burns, C, Chiang
Publikováno v:
The Journal of Prevention of Alzheimer's Disease.
The onset of mild cognitive impairment (MCI) is an essential outcome in Alzheimer's disease (AD) prevention trials and a compelling milestone for clinically meaningful change. Determining MCI, however, may be variable and subject to disagreement. Adj
Autor:
Suzanne Craft, William J. Bremner, John K. Amory, E. R. Peskind, Sanjay Asthana, Alvin M. Matsumoto, M. A. Raskind, Monique M. Cherrier
Publikováno v:
Neurology. 64(12)
Objective: To determine the efficacy of testosterone (T) supplementation on cognition in a sample of men with Alzheimer disease (AD) or mild cognitive impairment (MCI).Methods: Fifteen patients with AD and 17 patients with MCI aged 63 to 85 years com
Autor:
A F, Clark, H T, Steely, J E, Dickerson, S, English-Wright, K, Stropki, M D, McCartney, N, Jacobson, A R, Shepard, J I, Clark, H, Matsushima, E R, Peskind, J B, Leverenz, C W, Wilkinson, R E, Swiderski, J H, Fingert, V C, Sheffield, E M, Stone
Publikováno v:
Investigative ophthalmologyvisual science. 42(8)
To examine the intracellular and extracellular expression of myocilin in the human and primate trabecular meshwork (TM) in the presence and absence of glucocorticoids.Myocilin expression was examined in cultured human TM cells by Northern blot analys
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(2)
We have previously shown that when tested in the morning, older men and women, pretreated with metyrapone to block endogenous cortisol synthesis, exhibit delayed suppression of plasma ACTH in response to cortisol infusion. To confirm this finding and
Publikováno v:
Neurology. 54(12)
Galantamine is a reversible, competitive cholinesterase inhibitor that also allosterically modulates nicotinic acetylcholine receptors. These mechanisms of action provided the rationale for a therapeutic trial of galantamine in AD.A 6-month, multicen
Publikováno v:
Journal of neurochemistry. 73(5)
Galanin (GAL) innervation is hypertrophied in the basal forebrain and cortex of patients with Alzheimer's disease (AD). Increased GAL could exacerbate the cognitive and behavioral deficits of AD because GAL acts as an inhibitory modulator of choliner
Autor:
E R, Peskind
Publikováno v:
The Journal of clinical psychiatry. 59
This article reviews placebo-controlled studies addressing drug efficacy for the cognitive deficits of Alzheimer's disease. Efforts to compensate for the presynaptic cholinergic deficiency in Alzheimer's disease by pharmacologically inhibiting acetyl
Publikováno v:
Depression and anxiety. 7(3)
Autor:
E R, Peskind, J, Leverenz, M R, Farlow, R K, Ito, S A, Provow, R S, Siegel, M, Cleveland, C H, Morgan, M R, Pandian, S, Corbin, D, Nochlin, G D, Schellenberg, M A, Raskind, S L, Wagner
Publikováno v:
Alzheimer disease and associated disorders. 11(4)
The authors compared concentrations of soluble beta-amyloid protein precursor (s beta PP) in cerebrospinal fluid (CSF) in 45 patients diagnosed with probable Alzheimer disease (AD) and 26 normal older control volunteers. Soluble beta-amyloid protein
Publikováno v:
International journal of geriatric psychiatry. 12(10)
Most instruments that measure the impairments associated with Alzheimer's disease assess symptom severity. Little attention has been paid to the illness's impact on the time formal and informal caregivers spend caring for Alzheimer's individuals. A t