Zobrazeno 1 - 10
of 183
pro vyhledávání: '"E R, Chernykh"'
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1115-1120 (2024)
The T cell immunoglobulin domain and mucin domain-containing molecule-3 (TIM-3), an inhibitory checkpoint receptor, has been identified as a crucial regulator of cellular immune responses. TIM-3 has been discovered as a receptor involved in the negat
Externí odkaz:
https://doaj.org/article/15dbd7e19f9e4b9fa1a0e5151a391f90
Myeloid-derived suppressor cells in axial spondyloarthritis patients with different types of therapy
Autor:
A. Yu. Morenkova, T. V. Tyrinova, A. V. Fedorova, M. A. Tikhonova, N. A. Ilina, O. A. Chumasova, A. E. Sizikov, E. R. Chernykh
Publikováno v:
Научно-практическая ревматология, Vol 62, Iss 3, Pp 300-308 (2024)
Aim – to evaluate myeloid-derived suppressor cell (MDSC) subset counts and their suppressor potential in axial spondyloarthritis (axSpA) patients, as well as to analyze changes in the studied parameters in biological therapy (BT).Materials and meth
Externí odkaz:
https://doaj.org/article/56394c5e0f444b16b7e7db9b2e87bf83
Autor:
E. A. Smetanenko, N. A. Khonina, O. Y. Leplina, M. A. Tikhonova, E. V. Batorov, N. M. Pasman, E. R. Chernykh
Publikováno v:
Медицинская иммунология, Vol 25, Iss 6, Pp 1353-1362 (2023)
Maternal adaptation of the immune system aimed at limiting the immune response to fetal antigens is a necessary condition for a successful pregnancy. It involves various mechanisms (Th1/Th2 switching, Treg expansion, induction of anergy and apoptosis
Externí odkaz:
https://doaj.org/article/10d56335cc324d2db2e15d27911b904b
Autor:
V. S. Anmut, T. V. Tyrinova, E. V. Batorov, T. A. Aristova, S. A. Sizikova, G. Yu. Ushakova, V. V. Denisova, E. R. Chernykh
Publikováno v:
Медицинская иммунология, Vol 25, Iss 5, Pp 1159-1164 (2023)
Myeloid-derived suppressor cells (MDSCs) play an important role in the immune response regulation in many pathologies, primarily in malignant tumors, but their role in the hematopoietic stem cell engraftment and the hematopoietic recovery after high-
Externí odkaz:
https://doaj.org/article/a4b9214db1a5424c90986d05671182d2
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 507-512 (2023)
During pregnancy, the maternal immune system must maintain tolerance to paternal antigens, at the same time being able to eliminate pathogens, which is achieved by the weakening of adoptive immunity and the activation of innate immunity, in particula
Externí odkaz:
https://doaj.org/article/21322154f31e45a1babc88ac29a38a02
Autor:
E. V. Batorov, V. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, E. Ya. Shevela, A. A. Ostanin, E. R. Chernykh
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 1, Pp 43-54 (2023)
T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However, checkpoint expressing T cell compartment includes different subsets, and their dysregulation foll
Externí odkaz:
https://doaj.org/article/2100de4bd07d430e81843b1dcc778de9
Autor:
T. V. Tyrinova, E. V. Batorov, T. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, A. A. Ostanin, E. R. Chernykh
Publikováno v:
Сибирский онкологический журнал, Vol 21, Iss 6, Pp 47-58 (2023)
Introduction. Myeloid-derived suppressor cells (MDSCs) play an important role in restriction of the immune response and are associated with a poor prognosis in cancer. Mobilization of hematopoietic stem cells (HSCs) before high-dose chemotherapy (HCT
Externí odkaz:
https://doaj.org/article/f997b6b5c6eb4cdeb587a6e6292886bc
Autor:
E. Ya. Shevela, N. G. Bukhtueva, M. A. Tikhonova, O. Yu. Leplina, N. M. Pasman, E. R. Chernykh
Publikováno v:
Медицинская иммунология, Vol 24, Iss 6, Pp 1151-1158 (2022)
In humans circulating monocytes include classical (CD14++CD16- ), intermediate (CD14++CD16+) and non-classical/alternative (CD14+CD16++) monocytes, which in turn can be activated via the classical or alternative pathway. Pregnancy is accompanied by s
Externí odkaz:
https://doaj.org/article/fc07236983f7495f9293f0e4078a9897
Autor:
A. A. Maksimova, E. Ya. Shevela, L. V. Sakhno, M. A. Tikhonova, A. A. Ostanin, E. R. Chernykh
Publikováno v:
Медицинская иммунология, Vol 24, Iss 5, Pp 931-942 (2022)
GM-CSF and M-CSF, the hematopoietic colony-stimulating factors, induce various phenotypic changes in macrophage lineage populations and promote cell differentiation, respectively, into M1- and M2-like macrophages. The pro- and anti-inflammatory prope
Externí odkaz:
https://doaj.org/article/c607293a68484defb614c8318cb3f473
Autor:
E. A. Smetanenko, N. A. Khonina, O. Yu. Leplina, M. A. Tikhonova, E. V. Batorov, N. M. Pasman, E. R. Chernykh
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 3, Pp 87-95 (2022)
Background. Inhibitory receptors and their ligands (also called checkpoint molecules) are important feedback regulators of the immune response. However, their role in immunological adaptation during pregnancy remains poorly understood.The aim of the
Externí odkaz:
https://doaj.org/article/2fd2ceed56d547aba059e7aff33b8fa6