Zobrazeno 1 - 10
of 15
pro vyhledávání: '"E Q Lawson"'
Autor:
Randolph V. Lewis, Karen C. Thompson, C. Russell Middaugh, E Q Lawson, Ken Matsuno, Susan Vrona, Bryan L. Steadman
Publikováno v:
Biotechnology and Bioengineering. 40:8-15
The effect of surface adsorption on the structure and stability of proteins is a matter of increasing interest in biotechnology. Therefore, we have examined the effect of adsorption to silica on the thermal stability of 7 proteins employing different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab6e2160d12cef79ae71c8a5c0dfec9
https://doi.org/10.1002/bit.260400103
https://doi.org/10.1002/bit.260400103
Publikováno v:
Molecular immunology. 28(9)
Cryoimmunoglobulins are associated with numerous clinical problems ranging from collagen vascular disorders (rheumatoid arthritis and systemic lupus erythematosus) to infectious processes including HIV infection. The precise role of cryoglobulins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78389fc8dd24d7f96cc784d53e11af5
https://pubmed.ncbi.nlm.nih.gov/1656245
https://pubmed.ncbi.nlm.nih.gov/1656245
Publikováno v:
Journal of Biological Chemistry. 261:16385-16391
The interaction of three monoclonal rheumatoid factor IgM molecules with IgG antigens has been studied utilizing immunoglobulins isolated from three mixed cryoglobulins. Static light scattering measurements show that the stoichiometry of these immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d20349c0a853c19fd73c7c23d26715
https://doi.org/10.1016/s0021-9258(18)66577-9
https://doi.org/10.1016/s0021-9258(18)66577-9
Autor:
P A Trautman, C. Russell Middaugh, Deborah A. Mood, John A. Thomson, E Q Lawson, Bryan L. Steadman, Matthew J. Raymond
Publikováno v:
Biochemistry. 28:9653-9658
Differential scanning calorimetry was performed on the five major lens crystallin fractions [HM-alpha, alpha, beta H, beta L, and (beta s + gamma)] of the bovine lens as well as on more purified forms of alpha- and gamma-crystallins. All were found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f309f5b54bfd38a25e6207811620c9
https://doi.org/10.1021/bi00451a017
https://doi.org/10.1021/bi00451a017
Publikováno v:
Molecular Immunology. 24:897-905
The kinetics of the cryoprecipitation of two monoclonal IgG and two monoclonal IgM cryoimmunoglobulins, two IgM/IgG mixed cryoglobulins and a series of cold soluble monoclonal IgG and IgM immunoglobulins in the presence of polyethylene glycol have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365ebc0cecbb0ebd7ebf8aca9c8b249c
https://doi.org/10.1016/0161-5890(87)90001-0
https://doi.org/10.1016/0161-5890(87)90001-0
Publikováno v:
Immunological Investigations. 16:21-32
The direct calorimetric determination of heats of solution for four monoclonal and three mixed (IgM/IgG) cryoglobulins is described. Values obtained by differential scanning calorimetry (DSC) are compared to values of the apparent delta Hsol obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63f2f837eb89240688f374a98693ebd
https://doi.org/10.3109/08820138709055709
https://doi.org/10.3109/08820138709055709
Publikováno v:
The Journal of Immunology. 140:1218-1222
Inhibition of the cryoprecipitation of cryoimmunoglobulins by neutral salts suggests that intermolecular electrostatic (charge-charge) interactions are responsible for their abnormal solution properties. To test this hypothesis, H+ titration curves a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ec4cb1f972d04a626c676d7745244c
https://doi.org/10.4049/jimmunol.140.4.1218
https://doi.org/10.4049/jimmunol.140.4.1218
Autor:
E Q Lawson, David Harmatz, Duane T. Brandau, Julie G. Horsch, C. Russell Middaugh, Albert J. Sadler
Publikováno v:
Analytical Biochemistry. 138:44-51
A major problem encountered with the use of electronic spectroscopy in the analysis of biological materials in the ultraviolet, visible, and infrared region involves the limited range of the physical state of samples that can be examined. In an attem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1bb64bb2e0871a73b9848abc9b4920
https://doi.org/10.1016/0003-2697(84)90766-8
https://doi.org/10.1016/0003-2697(84)90766-8
Autor:
R Micanovic, Albert J. Sadler, E Q Lawson, D Harmatz, C R Middaugh, R D MacElroy, Duane T. Brandau
Publikováno v:
Journal of Biological Chemistry. 259:2910-2912
The compound N-cyclohexyl-2-pyrrolidone contains a substantial apolar region as well as a peptide bond-like moiety. This solvent, therefore, provides a useful model for protein interiors. Under certain conditions of temperature and salt concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb6a02525c36d6ec5d6b62fdd60956f
https://doi.org/10.1016/s0021-9258(17)43235-2
https://doi.org/10.1016/s0021-9258(17)43235-2
Publikováno v:
Journal of Biological Chemistry. 255:6532-6534
The thermodynamics of both normal and abnormal (disease-associated) protein solubility has been examined. It is shown that the atypical behavior of monoclonal cryoimmunoglobulins can be explained by the formation of one or a few additional electrosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7adbadd744d527d7564ae4fd5cb1861d
https://doi.org/10.1016/s0021-9258(18)43596-x
https://doi.org/10.1016/s0021-9258(18)43596-x