Zobrazeno 1 - 10
of 243
pro vyhledávání: '"E Poynter"'
Autor:
Deena B. Snoke, Emma Bellefleur, Hibba Tul Rehman, James A. Carson, Matthew E. Poynter, Kim L. Dittus, Michael J. Toth
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 6, Pp 2579-2590 (2023)
Abstract Background Cancer and its treatment can adversely affect skeletal muscle, impacting physical function, treatment response and survival. No studies, however, have comprehensively characterized these muscle adaptations longitudinally in human
Externí odkaz:
https://doaj.org/article/549d87eced324256bf75e7517991059f
Autor:
Bristy Sabikunnahar, Sydney Caldwell, Stella Varnum, Tyler Hogan, Karolyn G. Lahue, Birgit Rathkolb, Raffaele Gerlini, Nathalia R. V. Dragano, Antonio Aguilar‐Pimentel, Martin Irmler, Adrián Sanz‐Moreno, Patricia daSilva‐Buttkus, German Mouse Clinic Consortium, Johannes Beckers, Eckhard Wolf, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Jennifer L. Ather, Matthew E. Poynter, Dimitry N. Krementsov
Publikováno v:
Physiological Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Obesity is a global health problem characterized by excessive fat accumulation, driven by adipogenesis and lipid accumulation. Long non‐coding RNAs (lncRNAs) have recently been implicated in regulating adipogenesis and adipose tissue funct
Externí odkaz:
https://doaj.org/article/737caf1a9abf472aaf1a165f9f9cba24
Autor:
Ravishankar Chandrasekaran, Carolyn R. Morris, Isabella M. Butzirus, Zoe F. Mark, Amit Kumar, Dhemerson Souza De Lima, Nirav Daphtary, Minara Aliyeva, Matthew E. Poynter, Vikas Anathy, Anne E. Dixon
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Obesity is a risk factor for severe influenza, and asthma exacerbations caused by respiratory viral infections. We investigated mechanisms that increase the severity of airway disease related to influenza in obesity using cells derived from obese and
Externí odkaz:
https://doaj.org/article/102c1f06ace041a5879ef9e87c8fd3d8
Autor:
Sierra Bruno, Amelia Lamberty, Margaret McCoy, Zoe Mark, Nirav Daphtary, Minara Aliyeva, Kelly Butnor, Matthew E. Poynter, Vikas Anathy, Brian Cunniff
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
Mitochondria are multifaceted organelles necessary for numerous cellular signaling and regulatory processes. Mitochondria are dynamic organelles, trafficked and anchored to subcellular sites depending upon the cellular and tissue requirements. Precis
Externí odkaz:
https://doaj.org/article/17bd724d5f814b6eb7b99e328d2ef034
Autor:
Julie A. Dumas, Janice Y. Bunn, Michael A. LaMantia, Catherine McIsaac, Anna Senft Miller, Olivia Nop, Abigail Testo, Bruno P. Soares, Madeleine M. Mank, Matthew E. Poynter, C. Lawrence Kien
Publikováno v:
Aging Brain, Vol 3, Iss , Pp 100072- (2023)
Prior studies in younger adults showed that reducing the normally high intake of the saturated fatty acid, palmitic acid (PA), in the North American diet by replacing it with the monounsaturated fatty acid, oleic acid (OA), decreased blood concentrat
Externí odkaz:
https://doaj.org/article/aa2fdd5e15a6499a89819f772704768f
Autor:
Joseph J. Bivona III, Madeleine M. Mank, Renee D. Stapleton, D. Clark Files, Michael J. Toth, Matthew E. Poynter
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The abundance, anatomical distribution, and vascularity of skeletal muscle make it a potentially important contributor to local cytokine production and systemic cytokine abundance during inflammatory events. An orchestrated balance between the produc
Externí odkaz:
https://doaj.org/article/e7200224a5e04872808de9dd9aa86fda
Autor:
Cheryl van de Wetering, Allison M. Manuel, Mona Sharafi, Reem Aboushousha, Xi Qian, Cuixia Erickson, Maximilian MacPherson, Garrett Chan, Ian M. Adcock, Nazanin ZounematKermani, Florence Schleich, Renaud Louis, Eric Bohrnsen, Angelo D'Alessandro, Emiel F. Wouters, Niki L. Reynaert, Jianing Li, C. Roland Wolf, Colin J. Henderson, Lennart K.A. Lundblad, Matthew E. Poynter, Anne E. Dixon, Charles G. Irvin, Albert van der Vliet, Jos L. van der Velden, Yvonne M. Janssen-Heininger
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102160- (2021)
Background: Interleukin-1-dependent increases in glycolysis promote allergic airways disease in mice and disruption of pyruvate kinase M2 (PKM2) activity is critical herein. Glutathione-S-transferase P (GSTP) has been implicated in asthma pathogenesi
Externí odkaz:
https://doaj.org/article/15b547ec2ffe4663b0ec95d01314240a
Autor:
Marta Kokoszynska, Niki D. Ubags, Joseph J. Bivona III, Sebastian Ventrone, Leah F. Reed, Anne E. Dixon, Matthew J. Wargo, Matthew E. Poynter, Benjamin T. Suratt
Publikováno v:
Physiological Reports, Vol 9, Iss 22, Pp n/a-n/a (2021)
Abstract Obesity alters the risks and outcomes of inflammatory lung diseases. It is important to accurately recapitulate the obese state in animal models to understand these effects on the pathogenesis of disease. Diet‐induced obesity is a commonly
Externí odkaz:
https://doaj.org/article/97e72e2c38bc4d018834a6dcd11d9181
Autor:
Joseph J Bivona, Matthew E Poynter
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261618 (2021)
Current methods of small animal exercise involve either voluntary (wheel running) or forced (treadmill running) protocols. Although commonly used, each have several drawbacks which cause hesitancy to adopt these methods. While mice will instinctively
Externí odkaz:
https://doaj.org/article/6c7e12058bfc47c0b1c74a61485ac7d1
Autor:
Bristy Sabikunnahar, Sydney Caldwell, Stella Varnum, Tyler Hogan, Alexei Cooper, Karolyn G. Lahue, Joseph J. Bivona, Phoebe M. Cousens, Menelaos Symeonides, Bryan A. Ballif, Matthew E. Poynter, Dimitry N. Krementsov
Publikováno v:
The Journal of Immunology. 210:807-819
Thousands of long noncoding RNAs are encoded in mammalian genomes, yet most remain uncharacterized. In this study, we functionally characterized a mouse long noncoding RNA named U90926. Analysis of U90926 RNA levels revealed minimal expression across