Výsledky vyhledávání

Correlation between expression of CD44 splice variant v8-v9 and invasiveness of fibroblast-like synoviocytes in an in vitro system

Autor: T C A, Tolboom, A L, Huidekoper, I M, Kramer, E, Pieterman, R E M, Toes, T W J, Huizinga

Publikováno v: Clinical and experimental rheumatology. 22(2)

Rheumatoid arthritis is characterized by inflammation, hyperplasia of the synovial membrane, pannus formation and degradation of cartilage and bone. Fibroblast-like synoviocytes are thought to be involved in the invasion and subsequent degradation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5824444d82470d64cff39bdc08c0beb4
https://pubmed.ncbi.nlm.nih.gov/15083882

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Infection efficiency of type 5 adenoviral vectors in synovial tissue can be enhanced with a type 16 fiber

Autor: P H, Goossens, M J, Havenga, E, Pieterman, A A, Lemckert, F C, Breedveld, A, Bout, T W, Huizinga

Publikováno v: Arthritis and rheumatism. 44(3)

To obtain an adenoviral vector with increased infection efficiency in the synovial tissue compared with conventional vectors based on adenovirus serotype 5 (Ad5), without compromising the specificity of infection.Coxsackie adenovirus receptor (CAR) e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a27d52651b0976fabd191036c3a7e41
https://pubmed.ncbi.nlm.nih.gov/11263771

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The influence of synovial fluid on adenovirus-mediated gene transfer to the synovial tissue

Autor: P H, Goossens, R, Vogels, E, Pieterman, M J, Havenga, A, Bout, F C, Breedveld, D, Valerio, T W, Huizinga

Publikováno v: Arthritis and rheumatism. 44(1)

To determine the effect of synovial fluid (SF) from rheumatoid arthritis (RA) patients on adenovirus type 5 (Ad5)-mediated gene transfer to synoviocytes, and to explore new strategies for vector development based on the neutralization data obtained.S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53264b16936c5fae214a5f5d698c6262
https://pubmed.ncbi.nlm.nih.gov/11212175

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Akademický článek

Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the ⁶⁸Ga- and ¹⁷⁷Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2.

Autor: Läppchen, Tilman¹ (AUTHOR) tilman.laeppchen@insel.ch, Bilinska, Adrianna¹ (AUTHOR) adrianna.bilinska@extern.insel.ch, Pilatis, Eirinaios¹ (AUTHOR) eirinaios.pilatis@insel.ch, Menéndez, Elena¹ (AUTHOR) elena.menendez@insel.ch, Imlimthan, Surachet¹ (AUTHOR) surachet.imlimthan@helsinki.fi, Moon, Euy Sung² (AUTHOR) esmoon92@googlemail.com, Afshar-Oromieh, Ali¹ (AUTHOR) ali.afshar@insel.ch, Rösch, Frank² (AUTHOR) froesch@uni-mainz.de, Rominger, Axel¹ (AUTHOR) axel.rominger@insel.ch, Gourni, Eleni¹ (AUTHOR) eleni.gourni@insel.ch

Publikováno v: Molecules. Jul2024, Vol. 29 Issue 13, p1-17. 17p. 3 Color Photographs, 1 Diagram, 1 Chart, 8 Graphs.

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[Untitled]

Autor: Tctm van der Pouw Kraan, Ash A. Alizadeh, Pia V Kasperkovitz, T. J. M. Smeets, Cornelis L. Verweij, B Baltus, E Pieterman, Gary S. Firestein, Mike Fero, T Timmer, T.W.J. Huizinga, Nicolette L. Verbeet, PP Tak

Publikováno v: Arthritis Research & Therapy. 6:77

The molecular pathogenesis of rheumatoid arthritis (RA) is still poorly understood and its clinical course can vary widely. In a recent report we noted heterogeneity in global gene expression signatures between synovial tissue specimens from differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc825bbcefe4687f21d55d05a2c7c9ea
https://doi.org/10.1186/ar1119

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Akademický článek

Trachelogenin alleviates osteoarthritis by inhibiting osteoclastogenesis and enhancing chondrocyte survival.

Autor: Jiang, Tao^1,2 (AUTHOR), Zhang, Jiahui³ (AUTHOR), Ruan, Beite⁴ (AUTHOR), Xi, Xiaobing³ (AUTHOR), Yang, Zhuo⁵ (AUTHOR), Liu, Jianmin^1,2 (AUTHOR), Zhao, Hongyan^1,2 (AUTHOR) hyanzhao@163.com, Xu, Xing³ (AUTHOR) xuxing0510315@126.com, Jiang, Min³ (AUTHOR) jiangm263@163.com

Publikováno v: Chinese Medicine. 3/1/2024, Vol. 19 Issue 1, p1-17. 17p.

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Autor: E Pieterman, D Botstein, Ash A. Alizadeh, T.W.J. Huizinga, Patrick O. Brown, Pia V Kasperkovitz, CL Verweij, Mike Fero, Nicolette L. Verbeet, Louis M. Staudt, Ferdinand C. Breedveld, F. van Gaalen, Tctm van der Pouw Kraan

Publikováno v: Arthritis Research. 4:28

A potentially powerful way to gain insight in the complex pathogenesis of rheumatoid arthritis (RA) and to classify arthritides has arisen from cDNA microarray technology, which provides the opportunity to determine differences in gene expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f488747dd6437effe539ee1c5ce16a6d
https://doi.org/10.1186/ar468

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Akademický článek

Biomimetic Collagen Membranes as Drug Carriers of Geranylgeraniol to Counteract the Effect of Zoledronate.

Autor: Manzano-Moreno, Francisco Javier^1,2 (AUTHOR) crr@ugr.es, de Luna-Bertos, Elvira^2,3 (AUTHOR) elviradlb@ugr.es, Toledano-Osorio, Manuel⁴ (AUTHOR) mantoled@ucm.es, Urbano-Arroyo, Paula⁴ (AUTHOR) paulaurbanoarroyo7@gmail.com, Ruiz, Concepción^2,3,5 (AUTHOR) rosorio@ugr.es, Toledano, Manuel^2,4 (AUTHOR), Osorio, Raquel^2,4 (AUTHOR)

Publikováno v: Biomimetics (2313-7673). Jan2024, Vol. 9 Issue 1, p4. 18p.

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