Zobrazeno 1 - 10
of 652
pro vyhledávání: '"E Pearlman"'
Autor:
Syed Nabeel-Shah, Jyoti Garg, Kanwal Ashraf, Renu Jeyapala, Hyunmin Lee, Alexandra Petrova, James D. Burns, Shuye Pu, Zhaolei Zhang, Jack F. Greenblatt, Ronald E. Pearlman, Jean-Philippe Lambert, Jeffrey Fillingham
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into
Externí odkaz:
https://doaj.org/article/e4f36e6d55c941bfb45b7fa551f9ce48
Autor:
Kyra Kerkhofs, Jyoti Garg, Étienne Fafard-Couture, Sherif Abou Elela, Michelle S. Scott, Ronald E. Pearlman, Mark A. Bayfield
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
La proteins are conserved factors critical for the maturation of RNA polymerase III transcripts. In the ciliate T. thermophila and related alveolates, La proteins have a novel domain arrangement and are linked to a distinct pre-tRNA processing pathwa
Externí odkaz:
https://doaj.org/article/ff657c925cdb4b6d9d25c4e5168dea34
Autor:
Syed Nabeel-Shah, Jyoti Garg, Pata-Eting Kougnassoukou Tchara, Ronald E. Pearlman, Jean-Philippe Lambert, Jeffrey Fillingham
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100362- (2021)
Summary: We describe an optimized protocol for one-step affinity purification of FZZ-tagged proteins followed by mass spectrometry analysis for the identification of protein-protein interactions in the ciliate protozoan Tetrahymena thermophila. The F
Externí odkaz:
https://doaj.org/article/4286ef92df364718915a1b61ea21a98f
Autor:
Alejandro Saettone, Jyoti Garg, Jean-Philippe Lambert, Syed Nabeel-Shah, Marcelo Ponce, Alyson Burtch, Cristina Thuppu Mudalige, Anne-Claude Gingras, Ronald E. Pearlman, Jeffrey Fillingham
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-20 (2018)
Abstract Background The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attri
Externí odkaz:
https://doaj.org/article/56375229106346adae0c58fc7d881d4c
Akademický článek
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Autor:
Syed Nabeel-Shah, Jack Greenblatt, Jean-Philippe Lambert, Suzanne Wahab, Zhaolei Zhang, Hyunmin Lee, Jacob Fine, Marcelo Ponce, Ronald E. Pearlman, Edyta Marcon, Jeffrey Fillingham, Nujhat Ahmed, Kanwal Ashraf, Alejandro Saettone, Joanna Derynck, Shuye Pu, Jyoti Garg
Publikováno v:
Nucleic Acids Research
Retinoblastoma-binding proteins 4 and 7 (RBBP4 and RBBP7) are two highly homologous human histone chaperones. They function in epigenetic regulation as subunits of multiple chromatin-related complexes and have been implicated in numerous cancers. Due
Autor:
Takahiko Akematsu, Yasuhiro Fukuda, Jyoti Garg, Jeffrey S Fillingham, Ronald E Pearlman, Josef Loidl
Publikováno v:
eLife, Vol 6 (2017)
Based on observations of markers for DNA lesions, such as phosphorylated histone H2AX (γH2AX) and open DNA ends, it has been suggested that post-meiotic DNA double-strand breaks (PM-DSBs) enable chromatin remodeling during animal spermiogenesis. How
Externí odkaz:
https://doaj.org/article/a4c713a69255436faa25eb014dc3f472
Autor:
Jacob L Fine, Ronald E Pearlman
Publikováno v:
RNA. :rna.079598.123
Darwin’s assertion that “it is mere rubbish thinking, at present, of origin of life” (quoted from Peretó et al. 2009) is no longer valid. By synthesizing origin of life (OoL) research from its inception to recent findings, with a focus on (i)
Akademický článek
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Autor:
Jeffrey Fillingham, Jyoti Garg, Alejandro Saettone, Syed Nabeel-Shah, Kanwal Ashraf, Joanna Derynck, Anne-Claude Gingras, Jean-Philippe Lambert, Ronald E. Pearlman
Publikováno v:
Molecular Biology and Evolution
Epigenetic information, which can be passed on independently of the DNA sequence, is stored in part in the form of histone posttranslational modifications and specific histone variants. Although complexes necessary for deposition have been identified