Zobrazeno 1 - 10
of 149
pro vyhledávání: '"E P Geiduschek"'
Publikováno v:
Nature Structural Biology. 7:782-785
RNA polymerase from the hyperthermophile archaeon Pyrococcus furiosus (Pfu) forms specific and transcriptionally active complexes with its conjugate transcription factors TBP (the archaeal TATA binding protein homolog) and TFB (the archaeal homolog o
Publikováno v:
Journal of Biological Chemistry. 273:34042-34048
Bacteriophage T4 late promoters are transcribed by an RNA polymerase holoenzyme comprising the Escherichia coli core, E, the phage gene 55-encoded promoter recognition subunit, gp55, and the gene 33-encoded co-activator, gp33. Transcriptional initiat
Autor:
E P Geiduschek, K Wong
Publikováno v:
Journal of Molecular Biology. 284:195-203
Activation of transcription at bacteriophage T4 late promoters and coupling of late transcription to concurrent replication requires a peculiar transcriptional activator, the gp45 sliding clamp of the T4 DNA polymerase. In order to activate transcrip
Publikováno v:
Journal of Molecular Biology. 282:731-739
The TATA binding protein (TBP), which plays a central role in gene regulation as an essential component of all three nuclear transcription systems, sharply kinks the TATA box at two sites and severely contorts the intervening DNA segment. DNA constru
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 63:121-131
Publikováno v:
Proceedings of the National Academy of Sciences. 94:6718-6723
Almost all proteins mediating transcriptional activation from promoter-distal sites attach themselves, directly or indirectly, to specific DNA sequence elements. Nevertheless, a single instance of activation by a prokaryotic topologically linked DNA-
Publikováno v:
Molecular and Cellular Biology. 17:1868-1880
Transcription factor IIIB (TFIIIB), the central transcription factor of Saccharomyces cerevisiae RNA polymerase III, is composed of TATA-binding protein, the TFIIB-related protein Brf, and B". B", the last component to enter the TFIIIB-DNA complex, c
Publikováno v:
The EMBO Journal. 15:5032-5039
Bacteriophage T4 gene 45 protein, gp45, serves as the sliding clamp of viral DNA replication and as the activator of T4 late gene transcription. In the latter context, DNA tracking is an essential feature of the unique mechanism of action. T4 late pr
Publikováno v:
The EMBO Journal. 15:4414-4422
Bacteriophage T4 gene 45 protein (gp45) and Escherichia coli beta are DNA-tracking sliding-clamp proteins that increase processivity by tethering their conjugate DNA polymerases to DNA. gp45 also activates T4 late transcription. DNA loading of gp45 a
Publikováno v:
Genes & Development. 10:725-739
Saccharomyces cerevisiae transcription factor (TF) IIIB, a TATA-binding protein (TBP)-containing multisubunit factor, recruits RNA polymerase (Pol) III for multiple rounds of transcription. TFIIIC is an assembly factor for TFIIIB on TATA-less tRNA ge