Zobrazeno 1 - 5
of 5
pro vyhledávání: '"E P, Sipos"'
Autor:
E P, Sipos, H, Brem
Publikováno v:
Journal of neuro-oncology. 50(1-2)
The critical role of angiogenesis in the growth of solid tumors, including neoplasms of the central nervous system, has provided the impetus for research leading to the discovery of inhibitors of tumor neovascularization. The therapeutic potential of
Autor:
A K, Sills, J I, Williams, B M, Tyler, D S, Epstein, E P, Sipos, J D, Davis, M P, McLane, S, Pitchford, K, Cheshire, F H, Gannon, W A, Kinney, T L, Chao, M, Donowitz, J, Laterra, M, Zasloff, H, Brem
Publikováno v:
Cancer research. 58(13)
The novel aminosterol, squalamine, inhibits angiogenesis and tumor growth in multiple animal models. This effect is mediated, at least in part, by blocking mitogen-induced proliferation and migration of endothelial cells, thus preventing neovasculari
Autor:
L K, Fung, M G, Ewend, A, Sills, E P, Sipos, R, Thompson, M, Watts, O M, Colvin, H, Brem, W M, Saltzman
Publikováno v:
Cancer research. 58(4)
Polymeric interstitial chemotherapy increases survival of humans with recurrent gliomas and animals with transplanted tumors in the brain, but the relationship between rates of drug release from polymer implants and drug concentration in brain tissue
Publikováno v:
Journal of neuro-oncology. 32(2)
A young patient surviving four years after treatment for primary intracerebral small-cell osteosarcoma is reported. This 16-year-old girl presented with headaches, visual disturbance, and papilledema and was found to have a large, heavily calcified m
Autor:
E P, Sipos, H, Brem
Publikováno v:
Neurologic clinics. 13(4)
Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusse