Zobrazeno 1 - 9
of 9
pro vyhledávání: '"E P, Shumaĭ"'
Autor:
A A, Kushch, E P, Shumaĭ, L A, Glukhova, Iu A, Magakin, A S, Avetisian, A M, Kapantsian, E M, Karalova, I L, Grabovskaia
Publikováno v:
Voprosy virusologii. 39(2)
The accumulation of viral proteins p24 and gp41 in MT-4 cells was shown to occur asynchronously. No increase in the number of polydiploid cells, no polyploid mitoses or chromosome defects were found indicating the antiproliferative effect of HIV on M
Publikováno v:
Voprosy virusologii. 37(5-6)
A test system using monoclonal antibodies to HIV p24 was developed for solid-phase ELISA for detection of HIV antigen (AG) which helped detect the content of AG in samples with trace concentrations, less than 25 pg/ml. The test system can be used for
Publikováno v:
Voprosy virusologii. 36(4)
Immunization of BALB/c mice with natural purified HIV antigen, fusion of spleen cells with myeloma cells and subsequent selection of hybrid clones using recombinant gag antigen of HIV gave hybridomas producing monoclonal antibodies (MCA) to HIV. The
Publikováno v:
Doklady Akademii nauk SSSR. 300(4)
Publikováno v:
Voprosy virusologii. 32(5)
The sensitivity of test systems for radioimmunological detection of HBsAg prepared on the basis of polyclonal immunoglobulins, affinity polyclonal antibody (PCA) and monoclonal antibody (MCA) was compared. MCA ZhAK 22 and ZhAK 12 interacting with two
Publikováno v:
Voprosy virusologii. 32(4)
An optimal schedule for immunization of BALB/c mice has been found, providing a high yield of hybridoma clones producing monoclonal antibody (MCA) to hepatitis B virus surface antigen (HBsAg). Fourteen hybridomas of ZHAK series have been prepared. Th
Publikováno v:
Voprosy virusologii. 33(6)
Changes in subpopulations of OKT 3, OKT 4, OKT 8, HNK-I, B-IgM, and B-IgG-producing lymphocytes in carriers of HIV antibodies were studied. A decrease in OKT 4 helpers/inducers, an increase in OKT 8-suppressors of cytotoxic cells, HNK-I, Ia-positive
Publikováno v:
Molekuliarnaia genetika, mikrobiologiia i virusologiia. (12)
Fourteen hybridoma clones have been isolated producing the monoclonal antibodies to the surface antigen of the hepatitis B virus (HBsAg). Monoclonal antibodies have been shown to react in high titres with HBsAg in the reactions of PHA, PH and ELISA.
[Monoclonal antibodies, interacting with antigenic determinants of the human immunodeficiency virus]
Publikováno v:
Voprosy virusologii. 34(4)
Twenty-five hybridomas of CMK series were generated which produced monoclonal antibodies (MCA) to human immunodeficiency virus (HIV). The MCA were shown to react with HIV antigenic determinants in enzyme-immunoassays to titres 5 X 10(3)--10(5). It wa