Zobrazeno 1 - 10
of 12
pro vyhledávání: '"E P, Henske"'
Autor:
J. O. R. Hernandez, X. Wang, M. Vazquez-Segoviano, M. Lopez-Marfil, M. F. Sobral-Reyes, A. Moran-Horowich, M. Sundberg, D. O. Lopez-Cantu, C. K. Probst, G. U. Ruiz-Esparza, K. Giannikou, R. Abdi, E. P. Henske, D. J. Kwiatkowski, M. Sahin, D. R. Lemos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The lack of animal models for some human diseases precludes our understanding of disease mechanisms and our ability to test new therapies in vivo. Here the authors present a tissue bioengineering strategy for the study of a rare kidney tumor called a
Externí odkaz:
https://doaj.org/article/928c67a16e704b9e921c20f97413c1e4
Publikováno v:
Annals of neurology. 49(1)
The molecular pharmacologic basis of epileptogenesis in cortical tubers in the tuberous sclerosis complex is unknown. Altered transcription of genes encoding glutamatergic and gamma-aminobutyric acid (GABA)-ergic receptors and uptake sites may contri
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 12(5)
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by seizures, mental retardation, and hamartomatous tumors in multiple organs, including subependymal giant cell astrocytomas, cardiac rhabdomyomas, and renal angiomyolip
Autor:
T, Al-Saleem, L L, Wessner, B W, Scheithauer, K, Patterson, E S, Roach, S J, Dreyer, K, Fujikawa, J, Bjornsson, J, Bernstein, E P, Henske
Publikováno v:
Cancer. 83(10)
The tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by seizures, mental retardation, and benign tumors of the brain, heart, skin, and kidney. Malignant tumors also can occur in patients with tuberous sclerosis, partic
Publikováno v:
Cancer research. 58(21)
Tuberous sclerosis is an inherited syndrome associated with mutations in two tumor suppressor genes: TSC1 and TSC2. Tuberin, the product of TSC2, appears to be localized to the Golgi apparatus and may have a function in vesicular transport. The funct
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 11(7)
Angiomyolipomas can occur sporadically or in association with tuberous sclerosis complex (TSC). TSC is an autosomal dominant disorder characterized by seizures, mental retardation, and benign tumors of the brain, heart, kidney, and skin. Angiomyolipo
Autor:
E P, Henske, L L, Wessner, J, Golden, B W, Scheithauer, A O, Vortmeyer, Z, Zhuang, A J, Klein-Szanto, D J, Kwiatkowski, R S, Yeung
Publikováno v:
The American journal of pathology. 151(6)
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by seizures, mental retardation, and tumors of skin, brain, heart, and kidney. In this study, we focused on two of the most frequent tumors in TSC patients, renal angiom
Publikováno v:
Cancer. 78(8)
Chromophobe renal cell carcinoma (RCC) is a distinctive subtype of RCC with a more favorable prognosis than clear cell RCC. We describe the pathologic features of 23 solitary cases and 2 cases with coexistent papillary RCCs, 7 of which developed meta
Publikováno v:
The American journal of pathology. 149(4)
The tuberous sclerosis complex (TSC) is a multisystem autosomal dominant disorder characterized by seizures, mental retardation, and hamartomas. Patients with TSC have been reported to develop renal cell carcinomas (RCC) with increased frequency, an
Publikováno v:
Genes, chromosomescancer. 13(4)
Angiomyolipomas (AMLs) are renal tumors that occur both sporadically and in association with tuberous sclerosis (TSC). TSC is an autosomal dominant disorder characterized by hamartomatous lesions in multiple organs. Two TSC loci are recognized: TSC1