Zobrazeno 1 - 9
of 9
pro vyhledávání: '"E P, Böttinger"'
Publikováno v:
Chest. 120:43S-47
Transforming growth factor (TGF)-beta plays a central role in fibrosis, contributing both to the influx and activation of inflammatory cells, as well as to activation of fibroblasts to elaborate extracellular matrix. In the past few years, new insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0eb3bde6dc62843538b039ee7535ece
https://doi.org/10.1378/chest.120.1_suppl.s43-a
https://doi.org/10.1378/chest.120.1_suppl.s43-a
Publikováno v:
The Journal of clinical investigation. 108(6)
Primary and secondary forms of focal segmental glomerulosclerosis (FSGS) are characterized by depletion of podocytes and constitute a central manifestation of chronic progressive glomerular diseases. Here we report that podocytes undergo apoptosis at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2c957e8d2d7731c126a37a1e2d04f24
https://pubmed.ncbi.nlm.nih.gov/11560950
https://pubmed.ncbi.nlm.nih.gov/11560950
Publikováno v:
Journal of mammary gland biology and neoplasia. 6(1)
Ligands of the TGF-beta superfamily are unique in that they signal through transmembrane receptor serine-threonine kinases, rather than tyrosine kinases. The receptor complex couples to a signal transduction pathway involving a novel family of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb5242eb5b02dae04f813e6609c676ea
https://pubmed.ncbi.nlm.nih.gov/11467453
https://pubmed.ncbi.nlm.nih.gov/11467453
Autor:
B, Tang, K, de Castro, H E, Barnes, W T, Parks, L, Stewart, E P, Böttinger, D, Danielpour, L M, Wakefield
Publikováno v:
Cancer research. 59(19)
Transforming growth factor (TGF)-betas are multifunctional growth factors, the properties of which include the potent inhibition of epithelial cell growth. Expression patterns of TGF-betas and TGF-beta receptors in the normal prostate indicate that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0d2e1740d6d361651ed164d597b6eaf
https://pubmed.ncbi.nlm.nih.gov/10519393
https://pubmed.ncbi.nlm.nih.gov/10519393
Publikováno v:
Cancer research. 57(24)
To test the hypothesis that the transforming growth factor-beta (TGF-beta) system has tumor suppressor activity in the mammary gland, we have generated transgenic mice overexpressing a dominant-negative mutant form of the type II TGF-beta receptor, u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6027b0eb43dbb8692cc82e5736e856c
https://pubmed.ncbi.nlm.nih.gov/9407968
https://pubmed.ncbi.nlm.nih.gov/9407968
Autor:
J B, Kopp, V M, Factor, M, Mozes, P, Nagy, N, Sanderson, E P, Böttinger, P E, Klotman, S S, Thorgeirsson
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 74(6)
Several lines of evidence suggest that local production of transforming growth factor-beta (TGF-beta) contributes to renal disease, particularly to the accumulation of the extracellular matrix protein that characterizes glomerulosclerosis and interst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff5028188d00da491ede306cc394f088
https://pubmed.ncbi.nlm.nih.gov/8667617
https://pubmed.ncbi.nlm.nih.gov/8667617
Publikováno v:
Archives of internal medicine. 156(4)
In the absence of evidence of arteritis or Wegener's granulomatosis, the syndrome of lung hemorrhage and nephritis has been commonly associated with anti-glomerular basement membrane (GBM) antibodies. However, it has been increasingly recognized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::414d546c4fe0016d51598bfd65bea2ac
https://pubmed.ncbi.nlm.nih.gov/8607730
https://pubmed.ncbi.nlm.nih.gov/8607730
Publikováno v:
The Journal of biological chemistry. 269(44)
Transforming growth factor-beta 1 (TGF-beta 1) is a homodimeric protein stabilized by a single disulfide bridge between Cys77 on the respective monomers and two paired complementary hydrophobic interfaces between the two subunits. A TGF-beta 1 mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::444e4e11f51c464eb7ecc792cdb7befb
https://pubmed.ncbi.nlm.nih.gov/7961688
https://pubmed.ncbi.nlm.nih.gov/7961688
Publikováno v:
Arthritis and rheumatism. 35(11)
A 63-year-old woman, in whom a diagnosis of Sjögren's syndrome was initially made, proved to have systemic vasculitis with salivary gland involvement and necrotizing and crescentic glomerulonephritis. Antineutrophil cytoplasmic autoantibodies (ANCA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b15613436f288328b7e554290b8f820
https://pubmed.ncbi.nlm.nih.gov/1445456
https://pubmed.ncbi.nlm.nih.gov/1445456