Zobrazeno 1 - 10
of 40
pro vyhledávání: '"E N Knyazev"'
Autor:
D. V. Maltseva, O. V. Kindeeva, V. A. Petrov, G. A. Belyakova, A. Yu. Khristichenko, E N Knyazev, T. N. Gerasimenko, Sergey Nikulin
Publikováno v:
Russian Chemical Bulletin. 68:2344-2349
An in vitro placental barrier model based on human choriocarcinoma BeWo b30 cell line was considered as a method of preclinical study of the transport and toxicity of antitumor agents and other organic compounds. Low permeabilities were found for 5-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ba899b437ce9f7e55244b32bd24f66
https://doi.org/10.1007/s11172-019-2709-7
https://doi.org/10.1007/s11172-019-2709-7
Publikováno v:
Doklady Biochemistry and Biophysics. 494:219-221
In the present study, we assessed the role of annexin 13 membrane-binding protein (ANXA13) in the intracellular transport of vesicles containing type II ribosome-inactivating proteins (RIP-IIs). A modified human intestinal epithelial cell line HT29 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff6c5150edc6b5cc1e1468a8bdb5932
https://doi.org/10.1134/s1607672920040092
https://doi.org/10.1134/s1607672920040092
Publikováno v:
Doklady Biochemistry and Biophysics. 493:198-200
The role of proteasome proteins and proteins of the ERAD system in the cytotoxicity of type II ribosome-inactivating proteins ricin and viscumin was investigated. For this, the cell line of colorectal adenocarcinoma HT29, as well as the HT29-sh002 li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5d70c58adc9d9d3aeb223d9dbc1339
https://doi.org/10.1134/s1607672920040080
https://doi.org/10.1134/s1607672920040080
Autor:
S. V. Nikulin, E. N. Knyazev, T. N. Gerasimenko, S. A. Shilin, I. N. Gazizov, G. S. Zakharova, A. A. Poloznikov, D. A. Sakharov
Publikováno v:
Molecular Biology. 53:411-418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e3907914c26f105a65f3484f57b22a
https://doi.org/10.1134/s0026893319030130
https://doi.org/10.1134/s0026893319030130
Publikováno v:
Bulletin of Experimental Biology and Medicine. 166:788-792
The effect of low concentrations of miRNA on the ability of GeneChip miRNA 4.0 hybridization chips to evaluate their representation in the sample was studied. It is shown that the evaluation of the expression of 61 miRNAs is statistically significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a9a755fd0a39e68c2c979b321cc591
https://doi.org/10.1007/s10517-019-04441-z
https://doi.org/10.1007/s10517-019-04441-z
Autor:
Irina Tsypina, Ancha Baranova, E N Knyazev, D. V. Maltseva, S A Shilin, Andrey A. Poloznikov, D. A. Sakharov, Alexander G. Tonevitsky, Sergey Nikulin
Publikováno v:
BMC Systems Biology, Vol 13, Iss S1, Pp 3-11 (2019)
BMC Systems Biology
BMC Systems Biology
Background A cancer cell line originating from human epithelial colorectal adenocarcinoma (Caco-2 cells) serves as a high capacity model for a preclinical screening of drugs. Recent need for incorporating barrier tissue into multi-organ chips calls f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b1c6ea84cf13b8e0b8d07acfdffda5
http://link.springer.com/article/10.1186/s12918-019-0686-y
http://link.springer.com/article/10.1186/s12918-019-0686-y
Autor:
I M Tsypina, E N Knyazev, Gennady T. Sukhikh, Galina S. Zakharova, L. A. Astakhova, Alexander G. Tonevitsky
Publikováno v:
Bulletin of Experimental Biology and Medicine. 166:321-325
Hypoxia of trophoblast cells is an important regulator of normal development of the placenta. However, some pathological states associated with hypoxia, e.g. preeclampsia, impair the functions of placental cells. Oxyquinoline derivative inhibits HIF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5891dc6f7caecbe2b8009b3bbcda6ef
https://doi.org/10.1007/s10517-019-04342-1
https://doi.org/10.1007/s10517-019-04342-1
Publikováno v:
Doklady. Biochemistry and Biophysics
Abstract Choriocarcinoma cells BeWo b30 are used to model human placental trophoblast hypoxia using cobalt (II) chloride and hydroxyquinoline derivative (HD) as chemical inducers of hypoxia-inducible factor (HIF). In this study, it was shown that bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94aaea715d20212f939fa5d4c9651e01
https://pubmed.ncbi.nlm.nih.gov/34426922
https://pubmed.ncbi.nlm.nih.gov/34426922
Autor:
Paul S. Yu., E N Knyazev
Publikováno v:
Compulsory licensing in pharmaceutical industry.
In humans, trophoblast hypoxia during placental development can be a cause of serious pregnancy complications, such as preeclampsia and fetal growth restriction. The pathogenesis of these conditions is not fully clear and may be associated with chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2545a5a123f838822bb03f42b258edb0
https://doi.org/10.24075/brsmu.2021.021
https://doi.org/10.24075/brsmu.2021.021
Publikováno v:
Doklady. Biochemistry and biophysics. 493(1)
One of the main complications of pregnancy and causes of maternal and perinatal mortality is preeclampsia. The pathophysiology of preeclampsia is associated with the development of placenta and fetal hypoxia and secretion of a number of effective mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9a46a06d8e5d3fce011820af660671
https://pubmed.ncbi.nlm.nih.gov/32894466
https://pubmed.ncbi.nlm.nih.gov/32894466