Cell Biology and Signaling

Autor: M. Agarwal, R. Nitta, S. Dovat, G. Li, H. Arita, Y. Narita, S. Fukushima, K. Tateishi, Y. Matsushita, A. Yoshida, Y. Miyakita, M. Ohno, V. P. Collins, N. Kawahara, S. Shibui, K. Ichimura, S. A. Kahn, S. Gholamin, M.-P. Junier, H. Chneiweiss, I. Weissman, S. Mitra, S. Cheshier, T. Avril, A. Hamlat, P.-J. Le Reste, J. Mosser, V. Quillien, C. Carrato, A. Munoz-Marmol, L. Serrano, L. Pijuan, C. Hostalot, S. l. Villa, A. Ariza, O. Etxaniz, C. Balana, E. T. Benveniste, Y. Zheng, B. McFarland, D. Drygin, S. Bellis, M. Bredel, D. Lotsch, C. Engelmaier, S. Allerstorfer, M. Grusch, J. Pichler, S. Weis, J. Hainfellner, C. Marosi, S. Spiegl-Kreinecker, W. Berger, A. Bronisz, M. O. Nowicki, Y. Wang, K. Ansari, E. A. Chiocca, J. Godlewski, K. Brown, M. Kwatra, T. Bui, S. Zhu, D. Kozono, J. Li, D. Kushwaha, B. Carter, C. Chen, J. Schulte, M. Srikanth, S. Das, J. Zhang, J. Lathia, L. Yin, J. Rich, E. Olson, J. Kessler, A. Chenn, A. Cherry, B. Haas, Y. H. Lin, S.-E. Ong, N. Stella, C. P. Cifarelli, R. J. Griffin, D. Cong, W. Zhu, Y. Shi, P. Clark, J. Kuo, S. Hu, D. Sun, M. Bookland, N. Darbinian, A. Dey, M. Robitaille, M. Remke, D. Faury, C. Maier, A. Malhotra, N. Jabado, M. Taylor, S. Angers, A. Kenney, X. Ren, H. Zhou, M. Schur, A. Baweja, M. Singh, A. Erdreich-Epstein, J. Fu, D. Koul, J. Yao, N. Saito, S. Zheng, R. Verhaak, Z. Lu, W. K. A. Yung, G. Gomez, S. Volinia, C. Croce, C. Brennan, W. Cavenee, F. Furnari, S. G. Lopez, D. Qu, C. Petritsch, M. Gonzalez-Huarriz, G. Aldave, D. Ravi, A. Rubio, R. Diez-Valle, M. Marigil, P. Jauregi, B. Vera, A. A. d. l. Rocha, S. Tejada-Solis, M. M. Alonso, U. Gopal, J. Isaacs, M. Gruber-Olipitz, S. Dabral, S. Ramkissoon, A. Kung, E. Pak, J. Chung, M. Theisen, Y. Sun, V. Monrose, Y. Franchetti, D. Shulman, N. Redjal, B. Tabak, R. Beroukhim, J. Zhao, S. Buonamici, K. Ligon, J. Kelleher, R. Segal, D. Canton, P. Diaz, J. Scott, K. Hara, T. Kageji, Y. Mizobuchi, K. Kitazato, T. Okazaki, T. Fujihara, K. Nakajima, H. Mure, K. Kuwayama, T. Hara, S. Nagahiro, L. Hill, H. Botfield, K. Hossain-Ibrahim, A. Logan, G. Cruickshank, Y. Liu, M. Gilbert, N. Kyprianou, V. Rangnekar, C. Horbinski, Y. Hu, C. Vo, Z. Li, C. Ke, N. Ru, K. R. Hess, M. E. Linskey, Y.-a. H. Zhou, F. Hu, K. Vinnakota, S. Wolf, H. Kettenmann, P. J. Jackson, J. D. Larson, D. A. Beckmann, B. S. Moriarity, D. A. Largaespada, S. Jalali, S. Agnihotri, S. Singh, K. Burrell, S. Croul, G. Zadeh, S.-H. Kang, M. O. Yu, N.-H. Song, K.-J. Park, S.-G. Chi, Y.-G. Chung, S. K. Kim, J. W. Kim, J. Y. Kim, J. E. Kim, S. H. Choi, T. M. Kim, S.-H. Lee, S.-K. Kim, S.-H. Park, I. H. Kim, C.-K. Park, H.-W. Jung, M. Koldobskiy, I. Ahmed, G. Ho, A. Snowman, E. Raabe, C. Eberhart, S. Snyder, I. Gugel, A. Bornemann, G. Pantazis, S. Mack, D. Shih, N. Sabha, M. Tatagiba, B. Krischek, A. Schulte, K. Liffers, A. Kathagen, S. Riethdorf, M. Westphal, K. Lamszus, J. S. Lee, J. Xiao, P. Patel, J. Schade, J. Wang, B. Deneen, H.-R. Song, L. Leiss, C. Gjerde, H. Saed, A. Rahman, M. Lellahi, P. O. Enger, R. Leung, O. Gil, L. Lei, P. Canoll, S. Sun, D. Lee, A. S. W. Ho, J. K. S. Pu, X.-q. Zhang, N. P. Lee, P. J. R. Dat, G. K. K. Leung, D. Loetsch, E. Steiner, K. Holzmann, C. Pirker, J. Hlavaty, H. Petznek, B. Hegedus, T. Garay, T. Mohr, W. Sommergruber, W. J. Lukiw, B. M. Jones, Y. Zhao, S. Bhattacharjee, F. Culicchia, N. Magnus, D. Garnier, B. Meehan, S. McGraw, M. Hashemi, T. H. Lee, C. Milsom, N. Gerges, J. Trasler, R. Pawlinski, N. Mackman, J. Rak, Z. Maherally, A. Thorne, Q. An, E. Barbu, H. Fillmore, G. Pilkington, S. L. Tan, S. Tan, S. Choi, C. Potts, D. A. Ford, Z. Nahle, A. M. Kenney, L. Matlaf, S. Khan, A. Zider, E. Singer, C. Cobbs, L. Soroceanu, B. C. McFarland, S. W. Hong, R. Rajbhandari, G. B. Twitty, G. K. Gray, H. Yu, E. N. Benveniste, S. E. Nozell, M. Minata, S. Kim, P. Mao, J. Kaushal, I. Nakano, T. Mizowaki, T. Sasayama, K. Tanaka, K. Mizukawa, M. Nishihara, S. Nakamizo, H. Tanaka, M. Kohta, K. Hosoda, E. Kohmura, S. Moeckel, K. Meyer, P. Leukel, U. Bogdahn, M. J. Riehmenschneider, A. K. Bosserhoff, R. Spang, P. Hau, A. Mukasa, A. Watanabe, H. Ogiwara, H. Aburatani, J. Mukherjee, S. Obha, W. See, R. Pieper, R. Otsuka, D. Kung, T. Sinha, G. Meares, S. Nozell, M. Ott, U. Litzenburger, K. Rauschenbach, L. Bunse, S. Pusch, K. Ochs, F. Sahm, C. Opitz, A. von Deimling, W. Wick, M. Platten, P. Peruzzi, R. Read, T. Fenton, J. Wykosky, S. Vandenberg, I. Babic, A. Iwanami, H. Yang, P. Mischel, J. Thomas, M. W. Ronellenfitsch, A. L. Thiepold, P. N. Harter, M. Mittelbronn, J. P. Steinbach, Y. Rybakova, A. Kalen, E. Sarsour, P. Goswami, J. Silber, G. Harinath, B. Aldaz, A. W. M. Fabius, S. Turcan, T. A. Chan, J. T. Huse, A. M. Sonabend, M. Bansal, P. Guarnieri, C. Soderquist, J. Yun, B. Kennedy, J. Sisti, S. Bruce, R. Bruce, R. Shakya, T. Ludwig, S. Rosenfeld, P. A. Sims, J. N. Bruce, A. Califano, M.-T. Stockhausen, K. Kristoffersen, L. S. Olsen, H. S. Poulsen, B. Stringer, B. Day, G. Barry, M. Piper, P. Jamieson, K. Ensbey, Z. Bruce, L. Richards, A. Boyd, A. Sufit, T. Burleson, J. P. Le, A. K. Keating, T. Sundstrom, J. K. Varughese, P. Harter, L. Prestegarden, K. Petersen, F. Azuaje, C. Tepper, E. Ingham, L. Even, S. Johnson, K. O. Skaftnesmo, M. Lund-Johansen, R. Bjerkvig, K. Ferrara, F. Thorsen, H. Takeshima, S. Yamashita, K. Yokogami, S. Mizuguchi, H. Nakamura, J. Kuratsu, T. Fukushima, K. Morishita, Y. Tang, D. Vaka, S. Chen, A. Ponnuswami, Y.-J. Cho, M. Monje, T. Nakamura, D. Cahill, K. Tiemann, H. Hedman, S. P. Niclou, M. Timmer, R. Tjiong, G. Rohn, R. Goldbrunner, P. Stavrinou, M. Perrech, M. Tokita, S. Mikheev, D. Sellers, A. Mikheev, Y. Kosai, R. Rostomily, I. Tritschler, K. Seystahl, J. J. Schroeder, M. Weller, A. Wade, A. E. Robinson, J. J. Phillips, Y. Gong, Y. Ma, Z. Cheng, R. Thompson, Q.-W. Fan, C. Cheng, W. Gustafson, E. Charron, P. Zipper, R. Wong, J. Chen, J. Lau, C. Knobbe-Thosen, N. Jura, G. Reifenberger, K. Shokat, W. Weiss, S. Wu, J. Hu, T. Taylor, G. R. Villa, P. S. Mischel, S. L. Gonias, D. Yamashita, T. Kondo, H. Takahashi, A. Inoue, S. Kohno, H. Harada, S. Ohue, T. Ohnishi, P. Li, J. Ng, L. Yuelling, F. Du, T. Curran, Z.-j. Yang, D. Zhu, R. C. Castellino, E. G. Van Meir, G. Begum, Q. Wang, S.-S. Yang, S.-H. Lin, K. Kahle

Publikováno v: Neuro-Oncology. 12:iv7-iv25

The phylogenetically-conserved vertebrate transcription factor, NFIB, is an orchestrator of glial differentiation in the developing mammalian central nervous system. We found NFIB expression to be reduced in glioblastoma (GBM), the commonest and most

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c144cb46e36ff215bbfdcd415fdcc237
https://doi.org/10.1093/neuonc/noq116.s2

TGF-beta suppresses IFN-gamma induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression

Autor: Y J Lee, Y Han, H T Lu, V Nguyen, H Qin, P H Howe, B A Hocevar, J M Boss, R M Ransohoff, E N Benveniste

Publikováno v: The Journal of Immunology. 158:2065-2075

Recently, a non-DNA binding protein, class II transactivator (CIITA), has been shown to be required for constitutive and IFN-gamma-inducible class II MHC transcription. The cytokine TGF-beta inhibits IFN-gamma-induced class II MHC expression at the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8069e94aab415e03a607938ea2367acd
https://doi.org/10.4049/jimmunol.158.5.2065

Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes

Autor: Y J Lee, E N Benveniste

Publikováno v: The Journal of Immunology. 157:1559-1568

Class II MHC Ags are critical in the regulation of immune responses by presenting Ag to T lymphocytes, resulting in their activation and differentiation. Class II expression is rare in the normal central nervous system, but elevated expression on gli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5cf930c2cce2d468bdb2d09a1171873
https://doi.org/10.4049/jimmunol.157.4.1559

HIV glycoprotein 120 enhances intercellular adhesion molecule-1 gene expression in glial cells. Involvement of Janus kinase/signal transducer and activator of transcription and protein kinase C signaling pathways

Autor: P Shrikant, D J Benos, L P Tang, E N Benveniste

Publikováno v: The Journal of Immunology. 156:1307-1314

It is well established that the two major glial cells in the central nervous system (CNS), astrocytes and microglia, are key participants in mediating the neurologic dysfunction associated with HIV infection of the CNS. In this study, we investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::209b2df41a6b583bf4aeb2a6e47ef1be
https://doi.org/10.4049/jimmunol.156.3.1307

Cytokine-induced expression of vascular cell adhesion molecule-1 (VCAM-1) by astrocytes and astrocytoma cell lines

Autor: S J Rosenman, P Shrikant, L Dubb, E N Benveniste, R M Ransohoff

Publikováno v: The Journal of Immunology. 154:1888-1899

Astrocytes in the central nervous system (CNS) associate intimately with vascular endothelial cells and are integral to the blood-brain barrier (BBB). Leukocyte transmigration across the BBB is a cardinal feature of CNS inflammation, as observed in e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfd01bf8f9d4767d197bce1eb7373cc9
https://doi.org/10.4049/jimmunol.154.4.1888