Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E N, Mokhova"'
Publikováno v:
Biochemistry. Biokhimiia. 68(4)
At low Ca2+ concentrations the pore of the inner mitochondrial membrane can open in substates with lower permeability (Hunter, D. R., and Haworth, R. A. (1979) Arch. Biochem. Biophys., 195, 468-477). Recently, we showed that Ca2+ loading of mitochond
Publikováno v:
Biochemistry. Biokhimiia. 66(8)
Oxidative stress is one of the most frequent causes of tissue and cell injury in various pathologies. The molecular mechanism of mitochondrial damage under conditions of oxidative stress induced in vitro with low concentrations of FeSO4 and ascorbate
Publikováno v:
Biochemistry. Biokhimiia. 63(5)
Earlier it was shown that fatty acid-induced uncoupling in liver mitochondria is suppressed by the substrates of the aspartate/glutamate antiporter (V. N. Samartsev, A. V. Smirnov, I. P. Zeldi, O. V. Markova, E. N. Mokhova, and V. P. Skulachev (1997)
Autor:
Z G, Amerkhanov, E N, Mokhova
Publikováno v:
Biochemistry. Biokhimiia. 62(12)
Addition of 0.5-5 microM cytochrome c and 30 microM lauric acid to rat liver mitochondria stimulated the respiration rate. Stimulation of respiration by cytochrome c was prevented by cyclosporin A and was not observed in the absence of lauric acid. H
Autor:
V N, Samartsev, E N, Mokhova
Publikováno v:
Biochemistry. Biokhimiia. 62(5)
The action of cysteinesulfinate, the substrate of the aspartate/glutamate antiporter on the palmitate-induced uncoupling in rat liver mitochondria and the recoupling effect of glutamate, aspartate, and diethyl pyrocarbonate was studied. In the presen
Publikováno v:
Biokhimiia (Moscow, Russia). 59(6)
The uncoupling effect of 2-hexadecylmalonic acid (HDMA) and 2-tetradecylmalonic acid (TDMA), the dicarboxylic derivatives of stearic and palmitic acids, have been studied in heart mitochondria. The effects of these compounds and related fatty acids o
Publikováno v:
Biochemistry and molecular biology international. 32(6)
Permeabilization of inner mitochondrial membrane by palmitic acid in the presence of Ca2+ (cyclosporin A-sensitive stimulation of respiration, decrease of delta psi and high amplitude swelling) is accompanied by activation of the external pathway of
Publikováno v:
Biokhimiia (Moscow, Russia). 59(1)
It has earlier been established that conjugates of hydrophilic proteins with block copolymers of ethylene oxide and propylene oxide (proxanols) used at low concentrations decrease the oxidation of NAD-dependent substrates in mitochondria and cells. T
Autor:
G P, Kirillova, E N, Mokhova, V I, Dedukhova, A N, Tarakanova, V P, Ivanova, N V, Efremova, I N, Topchieva
Publikováno v:
Biotechnology and applied biochemistry. 18(3)
The membranotropic properties of block co-polymers and their protein conjugates were studied by their effect on the rate of oxygen consumption by isolated liver mitochondria and on thymus-derived lymphocytes. The block co-polymers consisted of poly(e
Publikováno v:
Biokhimiia (Moscow, Russia). 58(10)
Pathways and mechanisms of oxidative phosphorylation uncoupling by long-chain fatty acids in liver and muscle mitochondria are considered. A conclusion is drawn that there exist at least three different pathways of uncoupling by fatty acids, namely: